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Books in Immunology

Elsevier's Immunology collection equips researchers with valuable insights to address the complexities of the immune system and its role in health and disease, offering original research, insightful analysis, and current theory on diagnosing, managing, and advancing treatments for allergies, asthma, and immunologic disorders.

BooksJournals

    • Immunobiology of the Macrophage

      • 1st Edition
      • June 28, 2014
      • David S. Nelson
      • English
      • Paperback
        9 7 8 1 4 8 3 2 4 4 0 1 3
      • eBook
        9 7 8 1 4 8 3 2 7 4 7 7 5
      Immunobiology of the Macrophage presents an account of the state of knowledge of the immunobiology of the macrophage. The book’s contributors—immunol... of diverse scientific and geographic backgrounds—have been encouraged to give personal accounts of developments in their special fields of interest as well as critical surveys of the backgrounds leading to these developments. The book begins with a study on the functions of macrophages in the initiation and regulation of antibody responses in vitro. This is followed by separate chapters on topics such as the role of macrophages in making antigen more immunogenic and less tolerogenic; functional distinctions between macrophages at different sites; and the role of the macrophage in antigen recognition by T lymphocytes. Subsequent chapters examine interactions between macrophages and lymphocytes in the production of interferon and other mediators of cellular immunity; macrophage cell lines and their uses in immunobiology; and cytotoxic macrophages in allograft rejection.

    • Clinical Immunobiology

      • 1st Edition
      • Volume 3
      • June 28, 2014
      • Fritz H. Bach + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 0 2 9 1 4
      • eBook
        9 7 8 1 4 8 3 2 1 6 3 4 8
      Clinical Immunobiology, Volume 3 covers a variety of methods used for assaying the immune status of an individual. This volume is composed of 21 chapters and begins with a presentation of the background and issues to which clinical tests would be applied. The succeeding chapters outline the methodological procedures used in the analyses. Other chapters present some examples of the kinds of data that can be generated with the procedures used and provide guidelines for interpretation of the tests. The remaining chapters discuss the value of the immunological test procedures in differential diagnosis and analysis of diseases. These chapters also explore the usefulness of these procedures in prognosis of disease and the consequences of immunological manipulation undertaken for treatment or prevention of disease. This book will be of great value to clinical immunobiologists, biochemists, and researchers.

    • Aspects of Developmental and Comparative Immunology

      • 1st Edition
      • May 9, 2014
      • J. B. Solomon
      • English
      • Paperback
        9 7 8 1 4 8 3 1 7 3 9 0 0
      • eBook
        9 7 8 1 4 8 3 1 8 9 7 1 0
      Aspects of Developmental and Comparative Immunology contains the proceedings of the 1st Congress of Developmental and Comparative Immunology, held from July 27 to August 1, 1980 in Aberdeen, Scotland. The papers explore various aspects of developmental and comparative immunology and cover topics ranging from the major histocompatibility complex (MHC) and membrane immunoglobulins to idiotypes and diversity, comparative ontogeny, and evolution of lymphoid organ function. Comprised of 105 chapters, this volume begins with an overview of how the host immune system utilizes polymorphic MHC antigens as the principal tool for pseudo-self versus true self distinction. The reader is then introduced to the immunology of earthworms, membrane immunoglobulins, idiotypes, and diversity. Subsequent chapters focus on the evolution of lymphoid organs in vertebrates; differentiation clocks in comparative immunology of mammals and birds; immunorecognition in invertebrates such as insects and gastropods; and the phylogeny of leucocytes in vertebrates and invertebrates. The remaining sections deal with stem cells, immune responses of gut-associated lymphoepithelial tissue, and the ontogeny of resistance to infection as well as the ontogeny of killer cells. Finally, the immunology of fish, amphibians, reptiles, chickens, and mammals is examined. This monograph will be of interest to immunobiologists.

    • Methods in Virology

      • 1st Edition
      • June 28, 2014
      • Karl Maramorosch + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 4 3 1 8 4
      • eBook
        9 7 8 1 4 8 3 2 6 9 5 0 4
      Methods in Virology, Volume VII focuses on the methods used in virology, including radioimmunoassays, microscopy, hybridization, and mutagenesis. The selection first elaborates on monoclonal antibody techniques applied to viruses; competition radioimmunoassays for characterization of antibody reactions to viral antigens; and enzyme immunosorbent assays in plant virology. Discussions focus on the principles of enzyme immunosorbent assay, choice of enzyme and preparation of conjugate, determination of immunoglobulin class, and maintenance and specificity testing of hybridomas. The text then elaborates on electron microscopy for the identification of plant viruses in in vitro preparations and cloning and expression of viral antigens in Escherichia coli and other microorganisms, including influenza virus, expression of foreign coding sequences in Escherichia coli, hepatitis B virus, electron microscope, immunoelectron microscopy, and imaging of nucleic acids. The manuscript takes a look at the detection and characterization of subgenomic RNA in plant viruses; exploring the gene organization of baculoviruses; and spot hybridization for detection of viroids and viruses. Topics include application to viral diseases, mapping mutuations of baculoviruses, transcriptional mapping of baculovirus genomes, and genetic mapping by blot hybridization. The selection is a valuable source of information for researchers interested in the methods employed in virology.

    • General Immunology

      • 1st Edition
      • May 20, 2014
      • Edwin L. Cooper
      • English
      • Paperback
        9 7 8 0 0 8 0 2 6 3 6 9 4
      • eBook
        9 7 8 1 4 8 3 1 3 6 5 9 2
      General Immunology provides a general overview of the immune system. It presents topics in immunology from all living groups, treating cells, tissues, organs, and organismal levels of biological organization. The book contains 23 chapters organized into eight sections. Section I serves as an introduction to immunology—a science, a sketch of its history, some of its more recent contributors, something about gathering facts, immunology journals, and the entire biomedical enterprise of which immunology is just a part. Section II is devoted to antigens while Section III examines the immune system in chordates and the ontogeny of the immune system. Section IV on cells of the immune system covers monocytes, macrophages, the three granulocytic types, and mast cells. Section V deals with phagocytosis and the interaction of lymphocytes. Section VI is devoted to antigens in relation to antibody synthesis, antigen-antibody interactions, immunologlobulin structure, and immunologlobulin assembly. Section VII on organs of the immune system examines bone marrow, thymus, spleen, lymph nodes, and lymphoid aggregations. Section VIII discusses the evolution of the immune system. This text was written for advanced undergraduates. However, its comprehensiveness makes it useful to immunologists and biologists at all levels as well as medical students and clinicians.

    • Antigens, Lymphoid Cells and the Immune Response

      • 1st Edition
      • June 28, 2014
      • G. J. V. Nossal + 1 more
      • F. J. Dixon + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 0 5 5 2 6
      • eBook
        9 7 8 1 4 8 3 2 1 8 9 5 3
      Antigens, Lymphoid Cells, and the Immune Response deals with the nature and properties of antigens and with the functional anatomy and cell physiology of the mammalian lymphoid system which responds to antigens. The book discusses the central questions in cellular immunology; the antigens and the afferent limb of the immune response; and antibodies and the afferent limb of the immune response. The text also describes the organ distribution of antigens; the functional anatomy of the lymphoid system; and the behavior patterns of lymphoid cells. The microscopic and electron microscopic distribution of antigen in lymphoid organs; the interaction of antigens with cells of the reticuloendothelial system; and the interaction of antigen with lymphoid cells are also considered. The book further tackles the role of antigen in immunological tolerance; antibody production and tolerance dissociated; and antigen and lymphoid cells.

    • Reactions of Antibodies with Soluble Antigens

      • 1st Edition
      • May 10, 2014
      • Curtis A. Williams + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 0 7 1 5 5
      • eBook
        9 7 8 1 4 8 3 2 2 0 5 8 1
      Methods in Immunology and Immunochemistry, Volume III: Reactions of Antibodies with Soluble Antigens provides information pertinent to antigen–antibody and hapten–antibody reactions in vitro, in free solution and in gels. This book presents the development of research in immunology and immunochemistry. Organized into three chapters, this volume begins with an overview of protein–antiprotein reactions. This text then discusses the inhibitory activity of protein fragments, which suggested that antigenic combining sites of proteins were limited regions of the whole antigen molecule. Other chapters consider the measurement of inhibitory activity, which is still the principal assay to characterize antigenic sites of proteins. This book discusses as well the immunological techniques prior to the development of gel-diffusion methods. The final chapter deals with fluorescence labeling techniques that provide powerful approaches for exploring the thermodynamic and kinetic parameters of antigen–antibody interactions. This book is a valuable resource for mathematicians and immunologists.

    • International Congress for Microbiology

      • 1st Edition
      • May 16, 2014
      • Sam Stuart
      • English
      • Paperback
        9 7 8 0 0 8 0 1 2 2 5 1 9
      • eBook
        9 7 8 1 4 8 3 1 3 7 2 4 7
      IX International Congress for Microbiology discusses the genetic regulation of microbial metabolism. This book presents the recommendations and suggestions on the nomenclature and classification of viruses. Organized into eight parts encompassing 72 chapters, this compilation of papers starts with an overview of the genetic code, which expresses the relationship between nucleotide triplets in messenger RNA and amino acids in proteins. This text then discusses the two aspects of the regulation of the physiology of Escherichia coli. Other chapters explore the ergot alkaloids and examine the problem of ergot alkaloid production and biosynthesis. This book discusses as well the antibiotic inhibitors of protein synthesis that are major clinical drugs, including chloramphenicol, tetracycline, streptomycin, erythromycin, and other aminoglycosides. The final chapter deals with karyological investigation of the cells during transformation by Rous virus (RSV), which shows that these cells retain a diploid character. This book is a valuable resource for epidemiologists, microbiologists, and experts in infectious diseases.

    • Methods in Virology

      • 1st Edition
      • June 28, 2014
      • Karl Maramorosch + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 4 3 1 7 7
      • eBook
        9 7 8 1 4 8 3 2 6 2 2 3 9
      Methods in Virology, Volume V focuses on the methods used in virology, including hybridization, gel electrophoresis, freeze-etching technique, and ultracentrifugation. The selection first offers information on the fusion of cells for virus studies and production of cell hybrids; approaches to ultracentrifugation; and polyacrylamide gel electrophoresis of viral RNA. Discussions focus on applications to virological problems and analysis of results; analysis of the distribution of RNA on polyacrylamide gels after electrophoresis; and biological analysis of DNA components. The book then examines the polyacrylamide gel electrophoresis of viral proteins, DNA-RNA and DNA-DNA hybridization in virus research, and techniques of RNA-DNA hybridization in solution for the study of viral transcription. Topics include preparation of nucleic acids, hybridization and elution procedures that minimize RNA degradation, and procedures for acrylamide gel electrophoresis. The text takes a look at freeze-etching technique for the study of virus ultrastructure; procedures to increase virus yield from infected plants; and the immunoperoxidase technique. Concerns include principles of the immunoperoxidase technique, histochemical detection of peroxidase activity, sequence of events in virus infection, and factors affecting virus yield. The selection is a valuable source of data for researchers interested in the methods employed in virology.

    • Lymphocyte Differentiation, Recognition, and Regulation

      • 1st Edition
      • June 28, 2014
      • David H. Katz
      • F. J. Dixon + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 4 1 4 0 1
      • eBook
        9 7 8 1 4 8 3 2 7 4 0 7 2
      Lymphocyte Differentiation, Recognition, and Regulation provides an overview of the state of knowledge on cellular immunology. The focus is on animal work than on studies in man, although in certain areas human lymphocyte biology has been discussed in some detail. The book attempts to integrate information from diverse areas of cellular immunology, immunogenetics, and immunochemistry to form some cohesive concepts that can be perhaps utilized as a working foundation for students and investigators in various areas of immunology. The book begins with a general description of some of techniques and principles underlying the systems frequently employed in cellular immunology. This is followed by detailed analyses of lymphocyte differentiation, receptor function, and regulatory processes. The main points that emerge from such analyses are that the immune system is an infinitely complex and finely tuned network of cells, receptors, and molecules which interact with one another in a genetically controlled manner that is manifested ultimately in the process known as differentiation.

Related subjects

Applied immunology

Basic immunology

Immunological methods

Immunopathogenesis