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Books in Basic immunology

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Structural Biology in Immunology

  • 1st Edition
  • May 14, 2018
  • Chaim Putterman + 2 more
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 0 3 3 6 9 - 2
  • eBook
    9 7 8 - 0 - 1 2 - 8 0 3 3 7 0 - 8
Structural Biology in Immunology, Structure/Function of Novel Molecules of Immunologic Importance delivers important information on the structure and functional relationships in novel molecules of immunologic interest. Due to an increasingly sophisticated understanding of the immune system, the approach to the treatment of many immune-mediated diseases, including multiple sclerosis, systemic lupus erythematosus, rheumatoid arthritis, and inflammatory bowel disease has been dramatically altered. Furthermore, there is an increasing awareness of the critical role of the immune system in cancer biology. The improved central structure function relationships presented in this book will further enhance our ability to understand what defects in normal individuals can lead to disease.

Advances in Immunology

  • 1st Edition
  • Volume 138
  • May 3, 2018
  • Frederick Alt
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 8 1 5 1 8 8 - 4
  • eBook
    9 7 8 - 0 - 1 2 - 8 1 5 5 2 9 - 5
Advances in Immunology, Volume 138, the latest in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, with this release including chapters on Eosinophil Development, Disease Involvement, and Therapeutic Suppression, Immunoglobulin A responses to the microbiota, Unexpected roles for intracellular complement in the regulation of TH1 responses, Magnesium in T cell signaling, and immunological synapse and T cell signaling.

The Epigenetics of Autoimmunity

  • 1st Edition
  • Volume 5
  • April 25, 2018
  • Rongxin Zhang
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 8 0 9 9 1 2 - 4
  • eBook
    9 7 8 - 0 - 1 2 - 8 0 9 9 2 8 - 5
The Epigenetics of Autoimmunity covers a topic directly related to translational epigenetics. Via epigenetic mechanisms, a number of internal and external environmental risk factors, including smoking, nutrition, viral infection and the exposure to chemicals, could exert their influence on the pathogenesis of autoimmune diseases. Such factors could impact the epigenetic mechanisms, which, in turn, build relationship with the regulation of gene expression, and eventually triggering immunologic events that result in instability of immune system. Since epigenetic aberrations are known to play a key role in a long list of human diseases, the translational significance of autoimmunity epigenetics is very high. To bridge the gap between environmental and genetic factors, over the past few years, great progress has been made in identifying detailed epigenetic mechanisms for autoimmune diseases. Furthermore, with rapid advances in technological development, high-throughput screening approaches and other novel technologies support the systematic investigations and facilitate the epigenetic identification. This book covers autoimmunity epigenetics from a disease-oriented perspective and several chapters are presented that provide advances in wide-spread disorders or diseases such as systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), multiple sclerosis (MS), type 1 diabetes (T1DM), systemic sclerosis (SSc), primary Sjögren's syndrome (pSS) and autoimmune thyroid diseases (AITDs). These emerging epigenetic studies provide new insights into autoimmune diseases, raising great expectations among researchers and clinicians. This seminal book on this topic comprehensively covers the most recent advances in this exciting and rapidly developing new science. They might reveal not only new clinical biomarkers for diagnosis and disease progression, but also novel targets for potential epigenetic therapeutic treatment.

Immunology in the Twentieth Century

  • 1st Edition
  • April 24, 2018
  • Domenico Ribatti
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 1 6 1 4 5 - 6
  • eBook
    9 7 8 - 0 - 1 2 - 8 1 6 1 4 6 - 3
Immunology in the Twentieth Century: From Basic Science to Clinical Application grew out of common knowledge that those who survived many of the common infectious diseases rarely contracted the same disease again. This book charts the historical development of this vital branch of medicine in a concise volume, covering both the basic science involved and the clinical applications. Immunology as a distinctive subject developed in the mid-twentieth century as researchers started to understand how the adaptive immune system aids the defense against pathogens. The subject has grown in importance and diversified into specialist fields, such as immunohistochemistry, immunogenetics and immunopathology.

Advances in Cancer Research

  • 1st Edition
  • Volume 138
  • March 15, 2018
  • Kenneth D. Tew + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 8 1 5 1 2 7 - 3
  • eBook
    9 7 8 - 0 - 1 2 - 8 1 5 1 2 8 - 0
Advances in Cancer Research, Volume 138, the latest release in this ongoing, well-regarded serial provides invaluable information on the exciting and fast-moving field of cancer research. This volume presents original reviews on research bridging oncology and gene expression, with this volume covering unconventional approaches to modulating the immunogenicity of tumor cells, tumor dormancy and immunoediting, the emerging role of anti-apoptotic Bcl-2 family proteins in chemoresistance, Beclin-1 and autophagy, MDA-7/IL-24, and nanotechnology and medicine.

Advances in Immunology

  • 1st Edition
  • Volume 137
  • February 15, 2018
  • Frederick Alt
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 8 1 5 1 8 9 - 1
  • eBook
    9 7 8 - 0 - 1 2 - 8 1 5 5 3 0 - 1
Advances in Immunology, Volume 137, the latest in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, with this release including sections on Notch and T-Cell signaling/T-Cell memory, Single Cell Analysis of CD8+ and CD4+ T Cell Differentiation, New Developments in the Chemokine Field, the Role of Caveolin-1 in BCR and TCR Receptors, The Unusual Biochemistry of Bovine Immunoglobulins, and the Molecular Aspects of Allergens and Allergy.

Advances in Cancer Research

  • 1st Edition
  • Volume 137
  • January 24, 2018
  • Kenneth D. Tew + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 8 1 5 1 2 3 - 5
  • eBook
    9 7 8 - 0 - 1 2 - 8 1 5 1 2 4 - 2
Advances in Cancer Research, Volume 137, the latest release in this ongoing, well-regarded serial provides invaluable information on the exciting and fast-moving field of cancer research. This volume presents original reviews on research bridging oncology and gene expression, with this volume covering unconventional approaches to modulating the immunogenicity of tumor cells, tumor dormancy and immunoediting, the emerging role of anti-apoptotic Bcl-2 family proteins in chemoresistance, Beclin-1 and autophagy, MDA-7/IL-24, and nanotechnology and medicine.

Inmunología básica para medicina

  • 1st Edition
  • January 4, 2018
  • Isabel Olazabal Olarreaga + 1 more
  • Spanish
  • eBook
    9 7 8 - 8 4 - 9 1 1 3 - 3 6 2 - 9
Manual conciso que destaca la información básica en inmunología para el estudiante de Medicina y para estudiantes de otros grados de Ciencias de la Salud que tienen un primer contacto con la asignatura. Los dos autores de este texto, la Dra. Isabel Olazábal y el Dr. J.A. Arias Navalón desempeñan su actividad docente en la Facultad de Medicina de la Universidad Alfonso X el Sabio (Madrid). La Dra.Olazábal es la coordinadora de la asignatura de inmunologia y el Dr. Arias es el actual decano de la facultad de Medicina. Junto a ellos han colaborado otros autores especialistas en diferentes areas todos ellos con una amplia experiencia docente y una larga trayectoria en la práctica clínica. La obra cuenta además con el aval de la Fundación de la UAX. El texto se organiza en un total de 24 capítulos más 4 anexos que abordan específicamente temas relativos a patógenos, trasplantes, oncología y vacunas. Cada uno de los capítulos tiene una estructura muy homogénea y cuenta con un gran número de cuadros con fondo de color para resaltar conceptos ("ideas esenciales", "interés clínico...), así como cuadros orientativos para la preparación de seminarios. Al final de cada capítulo se incluye un resumen de los puntos más importantes. Es de destacar la magnífica iconografía a todo color que acompaña a la obra y que es propiedad de los autores. La mayoría son dibujos y representaciones esquemáticas que contribuyen a explicar los diferentes procesos inmunológicos que se producen en el cuerpo humano.

Selenium and Selenoproteins in Cancer

  • 1st Edition
  • Volume 136
  • October 19, 2017
  • Francesco Galli + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 8 1 2 0 1 6 - 3
  • eBook
    9 7 8 - 0 - 1 2 - 8 1 2 0 1 7 - 0
Selenium and Selenoproteins in Cancer, Volume 136, the latest release in the Advances in Cancer Research series, provides invaluable information on the fast-moving field of cancer research. This updated volume includes chapters on The epidemiology of selenium and human cancer, Selenium, epigenetics and cancer, Selenium status and cancer risk, Nutritional aspects of selenium and breast cancer risk: focus on cellular and molecular mechanisms, Selenoproteins in tumorigenesis and cancer progression, Selenoproteins and metastasis, The tumor microenvironment and inflammatory factors, and Selenium-dependent glutathione peroxidases during tumor development. This new release in the series presents original reviews on research regarding the prevention and treatment of cancer with selenium.

G Protein-Coupled Receptors in Immune Response and Regulation

  • 1st Edition
  • Volume 136
  • September 23, 2017
  • Arun K. Shukla
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 8 1 2 4 0 3 - 1
  • eBook
    9 7 8 - 0 - 1 2 - 8 1 2 4 0 4 - 8
G Protein-Coupled Receptors in Immune Response and Regulation, Volume 136 presents emerging concepts related to the role of GPCRs in immune response and regulation. Users will find updated chapters on a variety of topics, including Beta-adrenergic signaling in the onset and progression of asthma, the Emerging roles of Regulators of G protein signaling (RGS) proteins in the immune system, information on Kinin receptors in immune response and pathogenic infections, and sections on GPCR signaling in C. elegans and its implications in immune response, GPCR Kinases in Inflammatory response and signaling, and GRK2 in Inflammation: Regulation of T cell receptors and IgE signaling. Chapters in this book discuss not only the well-known aspects of GPCR signaling in immunology, but also presents many emerging paradigms that have not yet been reported in classical textbooks. Each chapter presents a forward-looking discussion, providing a glimpse of the tremendous potential associated with the specific receptor systems discussed.