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  • Neurobehavioral Manifestations of Neurological Diseases: Diagnosis & Treatment, An Issue of Neurologic Clinics

    • 1st Edition
    • Volume 34-1
    • Alireza Minagar + 2 more
    • English
    This important subject of Diagnosis of and Treatment for Neurobehavioral manifestations of neurologic disease is directed by three leaders of this field - Dr. Alizeza Minagar, Dr. Glen Finney, and Dr. Kenneth Heilman. Topics include: Neurobehavioral testing for mental status; Behavioral neurology of vascular neurology; Alzheimer's disease; Frontotemporal dementia; Traumatic brain injury; Parkinsonian Syndromes (e.g., Parkinson's disease, Lewy body dementia, progressive supranuclear palsy, corticobasal disease, multisystem atrophy); Behavioral neurology of multiple sclerosis and autoimmune encephalopathies; Infectious Diseases (Neuro-AIDS, Neurosyphilis, HSV); Neurobehavioral aspects of systemic disease; Neurobehavioral aspects of epilepsy; Behavioral neurology aspects of nutritional deficiencies; Neurobehavioral aspects of mitochondrial disease; and Medicinal-induced behavioral disorders.

  • Hepatitis C Virus: The Next Epidemic, An issue of Gastroenterology Clinics of North America

    • 1st Edition
    • Volume 44-4
    • K. Rajender Reddy
    • English
    There are over 180 million people with chronic HCV infection worldwide with between 2.7 and 3.9 million in the United States. Hepatitis C most significantly affects Asia and Africa, with rates up to 15% in countries such as Egypt and up to 30% in certain regions such as Punjab, Pakistan. Hepatitis C places a significant burden on the public health infrastructure, as it remains the leading cause of chronic liver disease, accounting for 50-75% of primary liver cancers and is responsible for 30% of all liver transplantations. It is estimated to have cost the United States $5.5 billion in 1997, comparable to the national cost of asthma, $5.8 billion in 1994.This number is only expected to grow as the current HCV population ages, increasing overall rates of compensated cirrhosis/end-stage liver disease. The evolution of directly acting anti-virals has ushered in a new era for chronic hepatitis C. Ongoing drug development strategy has involved targeting several replication steps of the virus and the hope is to see all oral therapies by late 2014 or early 2015. Thus we are at an exciting cross roads with regard to new information and challenges with HCV: rising disease burden with associated high costs, the challenges globally and in multiple patient populations, and the impending availability of effective and well tolerated treatments. Therefore there is a need to commission an exclusive issue of GCNA for HCV.

  • Hidradenitis Suppurativa, An Issue of Dermatologic Clinics

    • 1st Edition
    • Volume 34-1
    • Gregor B E Jemec
    • English
    The painful and often scarring disease hidradenitis suppurtiva is presented comprehensively in this issue of Dermatologic Clinics led by expert Gregor Borut Ernst Jemec. Topics include: Diagnosing hidradentis suppurativa; Prevalence, risk factors and co-morbidities of hidradentis suppurativa; Genetics of hidradentis suppurativa; Histopathology and imaging; Inflammatory mechanisms in hidradentis suppurativa; Microbiology of hidradentis suppurativa; Endocrinological aspects of hidradentis suppurativa; Role of mechanical stress in hidradenitis suppurativa; Randomized controlled trials of hidradentis suppurativa treatment; Antibiotic treatment of hidradentis suppurativa; Other medical treatments of hidradentis suppurativa; Surgical interventions in hidradentis suppurativa; Lasers and IPL in hidradenitis suppurativa; The Handicap of hidradentis suppurativa.

  • Corticosteroids, An Issue of Rheumatic Disease Clinics of North America

    • 1st Edition
    • Volume 42-1
    • Marcy B. Bolster
    • English
    Corticosteroids represent the most important and frequently used class of anti-inflammatory and immunosuppressant agents in the management of many rheumatological conditions. Included in this issue will be articles on the following topics: Glucocorticoid use in intra-articular and soft tissue injections, corticosteroids and osteoporosis, corticosteroids in lupus, ANCA associated vasculitis, and many more!

  • Equine Neonatology, An Issue of Veterinary Clinics of North America: Equine Practice

    • 1st Edition
    • Volume 31-3
    • Pamela A. Wilkins
    • English
    This issue on Equine Neonatology is guest edited by Pam Wilkins and covers topics such as: Imaging the Equine Neonatal Respiratory Tract: CT and Radiographs; Defining the Systemic Inflammatory Response Syndrome in the Equine Neonate;Ultrasonogra... Examination of the Equine Neonate: Thorax and Abdomen;The Equine Neonatal Cardiovascular System in Health and Disease;The Transition From Fetus to Neonate: The Renal System;Sepsis and Septic Shock in the Equine Neonate;The Equine Neonatal Acute Abdomen;Anesthesia of the Equine Neonate in Health and Disease;The Normal and Abnormal Equine Neonatal Musculoskeletal System, and more!

  • Transcatheter Mitral Valve Intervention, An Issue of Interventional Cardiology Clinics

    • 1st Edition
    • Volume 5-1
    • Jason H. Rogers
    • English
    This issue of the Interventional Cardiology Clinics edited by Jason Rogers covers various approaches, techniques, and therapies for Transcatheter Mitral Value Intervention. Topics include, but are not limited to: Echocardiographic Imaging of the Mitral Valve for Transcatheter Interventions, Use of Computed Tomography to Guide Mitral Interventions, Transseptal Puncture for Mitral Interventions, MitraClip Therapy for Mitral Regurgitation: Primary MR, Coronary Sinus-Based Approach to Mitral Regurgitation, and Transcatheter Mitral Valve Replacement.

  • Geriatric Oncology, An Issue of Clinics in Geriatric Medicine

    • 1st Edition
    • Volume 32-1
    • Harvey Jay Cohen + 1 more
    • English
    This issue of Clinics in Geriatric Medicine, devoted to Geriatric Oncology, is guest edited by Drs. Harvey J. Cohen and Arati V. Rao of Duke University Medical Center. Articles in this issue include: Cancer and Aging: General Principles, Biology and Geriatric Assessment; Cancer Screening in the Elderly; Cancer Survivorship: Management of Long-term Toxicities; Socioeconomic Considerations and Shared Care Models of Older Cancer Care; Palliative Care and Symptom Management; Management of Prostate Cancer in the Elderly; Management of Breast Cancer in the Elderly; Management of Lung Cancer in the Elderly; Colorectal Cancer in the Elderly; Myelodysplastic Syndrome and Acute Myeloid Leukemia in the Elderly; Chronic Lymphocytic Leukemia and Other Lymphoproliferative Disorders; and Monoclonal Gammopathies and Multiple Myeloma in the Elderly.

  • Cardiac Resynchronization Therapy: State of the Art, An Issue of Cardiac Electrophysiology Clinics

    • 1st Edition
    • Volume 7-4
    • Luigi Padeletti
    • English
    The latest developments in the field of Cardiac Resynchronization Therapy are featured in this issue of Cardiac Electrophysiology Clinics. The issue includes more than 20 articles in the following areas: heart failure; cost of heart failure; ventricular dissynchrony and resynchronization; assessment of dissynchrony; indication for CRT implantation; implantation technique; measures to improve CRT benefit on AF patients; and many more.

  • Endoscopic Cranial Base and Pituitary Surgery, An Issue of Otolaryngologic Clinics of North America

    • 1st Edition
    • Volume 49-1
    • Raj Sindwani + 2 more
    • English
    This issue on endoscopic cranial base and pituitary surgery is led by experts in the field of Otolaryngology and Neurosurgery. Otolaryngologists/He... and Neck surgeons Dr. Raj Sindwani and Dr. Troy Woodard join with Neurosurgeon Dr. Pablo Recinos to present a comprehensive clinical approach. Topics include: Building an endoscopic skull base program (room setup and key equipment / IGS); Skull Base Anatomy (corridors, intra and extradural); Imaging in skull base surgery – CT, MRI, CT cisternogram, intraop CT; Sellar lesions / pathology; Principles of endoscopic pituitary surgery ; Reconstruction of skull base defects – free graft, pedicle, TPF, alloderm; Lumbar drain utility (role of intrathecal fluorescein); Hemostasis in Skull Base Surgery (control of smaller vessels, maneuvers to minimize bleeding – warm irrigations, HOB up, embolization); Management of ICA Injury (intraop options, late complications); Meningioma; Esthesioneuroblastom... Cordoma; Sinonasal Malignancies of Skull Base; Craniopharyngioma; Endonasal approaches to the craniocervical junction; Medical complications of Pituitary/skull base surgery – (ie. SIADH, DI, Hypopit); Post-op management of skull base patient (postop Abx, imaging, debridements, topical irrigations, more..). Articles cover surgical procedure, surgical complications, and surgical anatomy as relevant to the clinical discussion.

  • Our Shrinking Globe: Implications for Child Safety, An Issue of Pediatric Clinics of North America

    • 1st Edition
    • Volume 63-1
    • Avinash Shetty
    • English
    Pediatricians in the Unites States and around the World continue to face a myriad of global health threats affecting child and adolescent health including: 1) infectious diseases of poverty [e.g. human immunodeficiency virus (HIV), tuberculosis, malaria, and neglected tropical diseases] in low-and middle-income countries (LMIC), especially in sub Saharan Africa; 2) emerging and reemerging infectious diseases (such as Ebola); 3) rise of non-communicable diseases (e.g. common mental disorders); 4) unintentional injuries; and 5) environmental health hazards (e.g. climate change). Despite the promising news about rapid declines in maternal and child mortality in the era of Millennium Development Goals (MDGs), which originated from the United Nation (UN) Millennium Declaration in 2000, only 20% and 7% of LMIC are currently on track to attain the maternal and child mortality targets. For example, 44% of deaths in children younger than 5 years occur in neonates. Besides discovery of life-saving interventions (e.g. development of new and improved vaccines) for maternal and child health, we also need to do a better job at bridging the knowledge-implementa... gap and increase the effectiveness of proven interventions. For example, despite the availability of effective vaccines to prevent pneumococcal pneumonia, rotavirus gastroenteritis, and human papilloma virus-related diseases (e.g. cervical cancer), use of these vaccines remain suboptimal in LMIC. We need to recognize that global health is also local public health. For example, improving access, equity and quality of care for orphans and vulnerable children, immigrant and newly arrived refugee children in the U.S. remains a challenge. Timely access to psychiatric care for children and adolescents with mental illness is a major concern. The explosion of new age technology (such as the internet) also poses a considerable risk to children and adolescents. Pediatricians also need to be aware of diverse socio-cultural determinants of health and ethical issues in global health service and delivery.This issue of Pediatric Clinics of North America aims to address the above crucial global health challenges affecting children and adolescents. As practicing pediatricians, we have the unique opportunity to influence local and global public health. In the post-MDG era (beyond 2015), collaborative partnerships between various disciplines and across research, education and service is vital to reduce health inequities in children worldwide.

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