Human Toxicology of Chemical Mixtures
Toxic Consequences Beyond the Impact of One-Component Product and Environmental Exposures
- 1st Edition - June 18, 2008
- Imprint: William Andrew
- Author: Harold Zeliger
- Language: English
- eBook ISBN:9 7 8 - 0 - 0 8 - 0 9 4 7 6 8 - 6
- eBook ISBN:9 7 8 - 0 - 8 1 5 5 - 1 9 8 4 - 3
This book considers how exposure to toxic mixtures affects the different physiological systems and organs, including the respiratory, cardiovascular, immunological,… Read more
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Request a sales quoteThis book considers how exposure to toxic mixtures affects the different physiological systems and organs, including the respiratory, cardiovascular, immunological, musculoskeletal, nervous and reproductive systems, as well as the various organs, including the kidneys, liver and skin.The author evaluates various sources of exposure, including air, water, and soil pollution; in utero exposure; chemicals contained in foods, cosmetics, and domestic cleaning products; adhesives and paints; industrial chemicals; pesticides; electromagnetic radiation; and chemicals ingested or inhaled during the use of alcohol, tobacco and narcotics.The book also examines the interplay between exposure to these mixtures and the prevalence of various diseases and conditions, including autism, attention deficit hyperactivity disorder (ADHD), developmental neurotoxicology, multiple chemical sensitivity (MSC), chronic fatigue syndrome (CFS), fibromyalgia (FM), Gulf war syndrome, cancer and cancer clusters. The author also discusses how exposure to these mixtures yields the above diseases and conditions in different populations: fetuses, infants, pre-adolescent children, adolescents and adults.Finally, the book addresses the profound policy implications for formulation, labeling and use of chemical products, and it proposes more stringent exposure limits and warning requirements in light of the newly recognized toxic effects that are directly attributable to the mixture of toxic lipophilic and hydrophilic chemicals.
- Addresses chemical mixtures, while most literature only deals with single chemicals exposure
- Explains why certain toxicological effects are observed
- Discusses diagnosis and treatment of injuries resulting from exposure
- Explores consequences of effects on product formulation, use, handling and required warnings
- Provides guidelines for safer development of personal care, cosmetic, industrial and consumer use products
Toxicologists, medical practitioners, industrial hygienists, safety personnel, chemical formulators in the chemical, personal care, cosmetic, pharmaceutical, industrial, and consumer chemical product industries, Other segments include food manufacturers, laboratory workers, environmental and OSHA training personnel, forensic investigators and attorneys involved in toxic torts litigation
PART I Introduction to Chemical Toxicology of MixturesIntroductionHealth Effects of Exposures to Chemical MixturesAbsorption of Chemical MixturesChemical ToxicologyPART II Exposures to Chemical MixturesScope and sources of toxic exposuresIn Utero ExposureAir PollutionWater PollutionSoil PollutionFoodChemicals In and Around The HomeSick Building SyndromeIndustrial ExposurePesticidesAlcohol and Tobacco: Recreational ToxinsElectromagnetic Radiation and Toxic ExposurePART III Mixture Effects on Body SystemsRespiratory SystemNervous SystemDevelopmental NeurotoxicologyAutism: Effect of Maternal Exposure to Neurotoxic ChemcialsAttention Deficit Hyperactivity Disorder (ADHD)Endocrine SystemToxic InfertilityTeratogensImmune SystemChemical Sensitivity: Multiple Chemical Sensitivity (MCS)SkinMusculoskeletal SystemCardiovascular SystemLiverKidneysCancerChildhood CancerCancer ClustersPART IV REGULATORY REQUIREMENTS, CONCLUSIONSRegulatory RequirementsConclusions
- Edition: 1
- Published: June 18, 2008
- No. of pages (eBook): 400
- Imprint: William Andrew
- Language: English
- eBook ISBN: 9780080947686
- eBook ISBN: 9780815519843
HZ
Harold Zeliger
Dr. Harold I. Zeliger holds a PhD in organic chemistry and has been a professor of chemistry and environmental science. He is a Certified Professional Chemist, a Board- Certified Forensic Examiner, and an EPA Certified Laboratory Director. Dr. Zeliger is the author of 51 technical publications, including basic research journal articles and patents. In his more than 40 years in the Chemical Process Industry, he has personally developed many industrial and consumer chemical products, designed chemical product warning labels and written Material Safety Data Sheets for toxic and flammable chemicals. Dr. Zeliger has investigated hundreds of toxic chemical exposures, environmental spills and discharges, chemical fires and explosions nationally and internationally. He has served repeatedly as an expert witness for both plaintiffs and defendants in chemical product, process, toxic exposure, environmental, flammable, intellectual property and subrogation claims. Dr. Zeliger has provided services for numerous forensic examinations, technology transfer and due diligence investigations. Dr. Zeliger’s research is in the area of chemical toxicology. His published work includes papers on the toxic effects of chemical mixtures and chemical causes of cancer clusters and two editions of Human Toxicology of Chemical Mixtures, Second Edition.
Affiliations and expertise
Toxic and Flammable Chemical Consultant and Expert Witness; Certified Professional Chemist and Board Certified Forensic Examiner; Technology Transfer and Due Diligence Investigator, USARead Human Toxicology of Chemical Mixtures on ScienceDirect