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Cancer Immunotherapy
Immune Suppression and Tumor Growth
- 1st Edition - April 28, 2011
- Editors: George C. Prendergast, Elizabeth M. Jaffee
- Language: English
- Paperback ISBN:9 7 8 - 0 - 1 2 - 4 0 5 4 7 2 - 1
- eBook ISBN:9 7 8 - 0 - 0 8 - 0 5 2 1 8 5 - 5
There has been major growth in understanding immune suppression mechanisms and its relationship to cancer progression and therapy. This book highlights emerging new principles of… Read more
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Request a sales quoteThere has been major growth in understanding immune suppression mechanisms and its relationship to cancer progression and therapy. This book highlights emerging new principles of immune suppression that drive cancer and it offers radically new ideas about how therapy can be improved by attacking these principles. Following work that firmly establishes immune escape as an essential trait of cancer, recent studies have now defined specific mechanisms of tumoral immune suppression. It also demonstrates how attacking tumors with molecular targeted therapeutics or traditional chemotherapeutic drugs can produce potent anti-tumor effects in preclinical models. This book provides basic, translational, and clinical cancer researchers an indispensable overview of immune escape as a critical trait in cancer and how applying specific combinations of immunotherapy and chemotherapy to attack this trait may radically improve the treatment of advanced disease.
* Offers a synthesis of concepts that are useful to cancer immunologists and pharmacologists, who tend to work in disparate fields with little cross-communication
* Drs Prendergast and Jaffee are internationally recognized leaders in cancer biology and immunology who have created a unique synthesis of fundamental and applied concepts in this important new area of cancer research
* Summarizes the latest insights into how immune escape defines an essential trait of cancer
* Includes numerous illustrations including: how molecular-targeted therapeutic drugs or traditional chemotherapy can be combined with immunotherapy to improve anti-tumor efficacy; and how reversing immune suppression by the tumor can cause tumor regression
* Drs Prendergast and Jaffee are internationally recognized leaders in cancer biology and immunology who have created a unique synthesis of fundamental and applied concepts in this important new area of cancer research
* Summarizes the latest insights into how immune escape defines an essential trait of cancer
* Includes numerous illustrations including: how molecular-targeted therapeutic drugs or traditional chemotherapy can be combined with immunotherapy to improve anti-tumor efficacy; and how reversing immune suppression by the tumor can cause tumor regression
Basic, translational, and clinical cancer researchers as well as practicing oncologists and their patients
- No. of pages: 428
- Language: English
- Edition: 1
- Published: April 28, 2011
- Imprint: Academic Press
- Paperback ISBN: 9780124054721
- eBook ISBN: 9780080521855
GP
George C. Prendergast
Affiliations and expertise
Lankenau Institute for Medical Research, Wynnewood, PA, U.S.A.EJ
Elizabeth M. Jaffee
Affiliations and expertise
Department of Oncology, SKCCC, Johns Hopkins University, Baltimore, MD, U.S.A.Read Cancer Immunotherapy on ScienceDirect