Molecular Therapy: Nucleic Acids

Molecular Therapy Nucleic Acids is an international, open-access journal publishing top-quality basic, translational, and clinical research in the broad fields of nucleic-acid-based therapeutics to treat and/or correct genetic and acquired disease. As an official journal of the American Society of Gene & Cell Therapy, Molecular Therapy Nucleic Acids builds upon the success of Molecular Therapy in publishing important peer-reviewed research, cutting-edge reviews, and commentaries targeted to advances in gene- and oligonucleotide-based therapies. Molecular Therapy Nucleic Acids's 2024 impact factor is 6.1

Subject areas include but are not limited to: development of therapeutics based on nucleic acids and their derivatives, vector development and design for the delivery of RNA-based therapeutics, applications of gene-modifying agents including triplex-forming oligonucleotides and enzymes such as Zn finger nucleases, pre-clinical target validation, safety/efficacy studies, and clinical trials.

To accommodate the rapid growth of Molecular Therapy Nucleic Acids, starting in 2022, articles will be submitted and published in one of six subsections covering key topics.

Subsections include:

• Bioinformatics

• AI

• NGS

• mathematical modeling

• phylogenetic oligo arrays

Delivery strategies

• chemistry

• ligands

• lipid nanoparticles

• localized delivery applications

• polymeric nanoparticles

• systemic delivery

• targeted delivery

• viral vectors

Non-coding RNAs

• circRNAs

• lncRNAs

• miRNAs

• siRNAs

• regulatory RNAs

Oligonucleotides: diagnostics and biosensors

• aptamer-based biosensors

• molecular beacons

• nanostructured biosensors

• radiolabeled oligonucleotides

• rolling circle amplification-based biosensors

Oligonucleotides: therapies and applications

• clinical studies

• CMC

• development

• discovery

• preclinical assessment

• regulatory RNAs

RNA/DNA editing

• ADAR

• CRISPR

• HDR

• NHEJ

• TALEN

• ZFN

Visit the Cell Press website for more information about Molecular Therapy Nucleic Acids - https://www.cell.com/molecular-therapy-family/home