Journal of Inorganic Biochemistry

The emphasis of the Journal is on interdisciplinary research covering the structure and mechanism of action of metallo-biomolecules primarily at the molecular level. The Journal reports on the chemistry, biochemistry and the structure-function relationships of the following systems:

• metallo-proteins and metallo-chaperones in homeostasis and trafficking
• metal-dependent gene regulation and signalling
• interaction of metal ions as well as coordination and organometallic compounds with nucleic acids, other biomolecules and reactive species
• metal-containing molecules in medicine, including therapeutics, imaging agents for diagnosis and theranostics
• metalloneurochemistry and the role of metal ions in sensory perception
• regulatory role of metals in immunology
• synthesis and application of metal ion sensors in biological systems
• natural and artificial metallo-enzymes
• synthesis and properties of metal complexes as structural and functional models of metallo-biosites
• preparation, structural characterization and mode of action of synthetic metallo-bionanomaterials
• molecular mechanisms of toxicity of metals and metalloids and their complexes, and their chemistry in the environment
• computational studies of metallo-biomolecules and their synthetic models
• biophysical, analytical and spectroscopic methods to study metallo-biomolecules

Manuscripts involving nanoparticles or metal-organic frameworks (MOFs) may be suitable for submission to the Journal of Inorganic Biochemistry only if such materials are specifically used to investigate the transport, sensing, or detection of metallo-proteins or metallo-pharmaceuticals, or as metallo-enzyme mimics. Manuscripts focused only on the properties of metal-based nanoparticles and/or their biological effects, without providing the molecular details of these effects, should be directed to journals specializing in materials or nanoscience. These guidelines ensure that submissions align with the journal’s emphasis on metal-biological interactions and biochemistry, maintaining a clear focus distinct from general nanoparticle and materials science research.