Genetics in Medicine Open

Genetics in Medicine Open (GIM Open) is an open access journal with a broad focus on medical genetics and genomic medicine, including all aspects of therapy. It has a strong emphasis on diversity, equity, and inclusion and uses a double anonymous review process for submitted manuscripts.

Positioned as an official journal of the American College of Medical Genetics and Genomics and the companion journal of Genetics in Medicine, GIM Open is an international journal publishing scientific works that advance the knowledge, understanding, and practice of medical genetics and genomic medicine for all continents. GIM Open welcomes submissions of Original Research, Reviews, Commentaries and Brief Reports in the areas of clinical genetics, cytogenetics, molecular genetics, biochemical genetics, reproductive medicine, cancer genetics, pharmacogenomics, clinical trials, population genetics, public health, genome-wide association studies, polygenic risk, bioinformatics, methodologies, clinical implementation, ELSI (ethical, legal, and social issues), genetic counseling, and practice standards and guidelines.

GIM Open welcomes submissions of data-driven, hypothesis-based and scientifically rigorous exploratory research that innovates or implements new science and technologies in genomic medicine. Manuscripts reporting animal models providing clinically relevant insights into human disease mechanisms and potential therapeutics are also welcome. Manuscripts of candidate disease gene discoveries based on a small cohort size but solidified by a high standard of scientific rigor, validity, and reproducibility may be considered. Rare case reports may be considered if they fill a knowledge gap in populations underrepresented in genetics research or experiencing health disparities, or inform exceptionally significant actionability in diagnosis, prognosis, and therapeutics. GIM Open promotes studies that include diverse, especially under-represented, populations.