
Whitcup and Nussenblatt's Uveitis
Fundamentals and Clinical Practice
- 5th Edition - March 31, 2021
- Imprint: Elsevier
- Authors: Scott M. Whitcup, H. Nida Sen
- Language: English
- Hardback ISBN:9 7 8 - 0 - 3 2 3 - 4 8 0 1 4 - 7
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 7 8 9 5 9 - 2
Comprehensive and readable, Whitcup and Nussenblatt's Uveitis, 5th Edition, covers every aspect of this complex subspecialty in a single convenient volume. This clinically relevant… Read more

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Request a sales quoteComprehensive and readable, Whitcup and Nussenblatt's Uveitis, 5th Edition, covers every aspect of this complex subspecialty in a single convenient volume. This clinically relevant guide covers the medical, pharmacological, and surgical treatment of uveitis in a visually rich, full-color format, offering a complete overview for today’s clinicians. New and updated case studies, key points boxes, and more than 400 images and graphics highlight major clinical points and provide insight into real situations that you can apply in practice.
- Features multiple chapters on diagnostic approach to help you meet the challenge of making accurate diagnoses.
- Reflects advancements and new developments on all aspects of uveitis including new medical and surgical treatments.
- Covers key topics such as the use of PCR in diagnostic testing, cataract surgery in patients with uveitis, the use of OCT in diagnosis and treatment, new infectious causes of uveitis (including Zika and Ebola), and novel treatments for inflammatory eye disease.
- Includes new clinical photographs, illustrations, and OCT images throughout.
- Reviews new randomized clinical trials of new uveitis therapy, as well as the approach to patients with HIV and HIV-associated ocular diseases including CMV retinitis and immune recovery uveitis.
- Provides expanded information on masquerade syndromes with important tips on diagnosis and management of intraocular lymphoma.
- Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Ophthalmologists, uveitis sub-specialists and fellows
- Cover image
- Title page
- Table of Contents
- Copyright
- Foreword
- Preface to the Fifth edition
- Acknowledgments
- Dedication
- Part 1. Fundamentals
- 1. Elements of the Immune System and Concepts of Intraocular Inflammatory Disease Pathogenesis
- Elements of the immune system
- Concepts of disease pathogenesis
- Immunogenetics
- T-cell receptor and the expression of disease
- Part 2. Diagnosis
- 2. Medical History in the Patient with Uveitis
- 3. Clinical Examination of the Patient with Uveitis
- Visual Acuity
- External Examination
- Pupils and Extraocular Muscles
- Intraocular Pressure Measurement
- Conjunctiva
- Cornea
- Anterior Chamber
- Iris
- Anterior Chamber Angle
- Lens
- Vitreous
- Retina and Choroid
- Optic Nerve
- 4. Development of a Differential Diagnosis
- Forming A Differential Diagnosis
- Computers in Diagnosis
- 5. Diagnostic Testing and Imaging
- Pretest likelihood of disease
- Diagnostic tests for uveitis
- Ophthalmic imaging
- Ancillary ophthalmic tests
- Other diagnostic tests
- 6. Optical Coherence Tomography in Uveitis
- Macular Edema
- Retinal And Choroidal Pathology
- Examples of Optical Coherence Tomography In Specific Uveitic Diseases
- Optical Coherence Tomography Angiography
- Summary
- 7. Evidence-Based Medicine in Uveitis
- Study Design
- Uveitis Clinical Trials
- Part 3. Medical Therapy and Surgical Intervention
- 8. Approaches to Medical Therapy
- Goals and Philosophy
- Nonsurgical Therapeutic Options
- Other Therapeutic Approaches
- Caution
- 9. Role of Surgery in the Patient with Uveitis
- Considerations
- Removal of Band Keratopathy
- Corneal Transplantation
- Cataract Surgery
- Glaucoma Surgery
- Treatment of Vitreoretinal Disease
- Laser Treatment
- Diagnostic Surgery
- Part 4. Infectious Uveitic Conditions
- 10. Bacterial and Fungal Diseases
- Introduction
- Leprosy
- Tuberculosis
- Other Bacterial Infections
- Chronic Granulomatous Disease
- Fungal Disease
- 11. Spirochetal Diseases
- Spirochetal Infections And The Eye
- Spirochetes
- 12. Acquired Immunodeficiency Syndrome
- Human Immunodeficiency Virus
- CMV Retinitis
- Herpes Zoster
- Pneumocystis jirovecii choroiditis
- Mycobacterium avium-intracellulare choroiditis
- Other Diseases
- Drug-Related Ocular Inflammation
- Summary
- 13. Acute Retinal Necrosis and Progressive Outer Retinal Necrosis
- Acute Retinal Necrosis
- Progressive Outer Retinal Necrosis
- 14. Other Viral Diseases
- Herpes Simplex Virus–Associated Keratitis And Keratouveitis
- Herpes Zoster Ophthalmicus
- West Nile Virus
- Zika Virus
- Ebola Virus
- Severe Acute Respiratory Syndrome Coronavirus 2 (Sars-Cov-2)
- Other Viral Infections
- Summary
- 15. Ocular Toxoplasmosis
- Organism And Transmission
- Clinical Manifestations
- Histopathology And Immune Factors
- Therapy
- 16. Ocular Histoplasmosis
- Systemic Findings
- Ocular Appearance
- Etiology And Immunology
- Nonsurgical Therapies
- Subretinal Surgery
- 17. Ocular Toxocariasis
- Life Cycle
- Epidemiology
- Clinical Syndromes
- Ocular Manifestations
- Diagnosis
- Treatment And Prognosis
- 18. Onchocerciasis and Other Parasitic Diseases
- Onchocerciasis
- Giardiasis
- Ophthalmomyiasis
- Cysticercosis
- Caterpillar setae
- Amebiasis
- Diffuse Unilateral Subacute Neuroretinitis
- Malaria
- Seasonal Hyperacute Panuveitis
- 19. Postsurgical Uveitis
- Acute Bacterial Endophthalmitis
- Chronic Bacterial Endophthalmitis
- Fungal Endophthalmitis
- Endogenous Endophthalmitis
- Lens-Induced Uveitis
- Toxic Anterior Segment Syndrome
- Persistent Postoperative Anterior Uveitis
- Laser-Induced Uveitis
- Part 5. Noninfectious Uveitic Conditions
- 20. Anterior Uveitis
- Epidemiology
- Clinical Description
- Idiopathic Anterior Uveitis
- Hla-B27–Associated Anterior Uveitis
- Hla-B27–Associated Anterior Uveitis With Systemic Disease
- Disease Associations
- 21. Scleritis
- Episcleritis
- Scleritis
- Disease Associations
- Prognosis
- 22. Intermediate Uveitis
- Epidemiology
- Etiology
- Clinical Manifestations
- Diagnosis
- Multiple Sclerosis
- Treatment
- Prognosis
- 23. Sarcoidosis
- Epidemiology
- Etiology
- Clinical Manifestations
- Pathology
- Diagnosis
- Treatment
- Prognosis
- 24. Sympathetic Ophthalmia
- Clinical Appearance and Prevalence
- Tests and Immunologic Characteristics
- therapy
- 25. Vogt-Koyanagi-Harada Syndrome
- Clinical Aspects
- Laboratory Tests, Etiology, and Histopathology
- Therapy
- 26. Birdshot Chorioretinopathy
- Clinical Manifestations
- Tests, Histology, And Etiology
- Therapy
- 27. Behçet Disease
- Clinical Manifestations
- Immunologic and Histologic Considerations
- Therapy
- 28. Retinal Vasculitis
- Clinical Characteristics
- Ocular Vasculitis Without Systemic Disease
- Ocular Vasculitis With Systemic Disease
- 29. Serpiginous Choroiditis
- Epidemiology
- Clinical Features
- Pathology
- Etiology
- Differential Diagnosis
- Therapy
- Prognosis
- 30. White-Dot Syndromes
- Multiple Evanescent White-Dot Syndrome
- Multifocal Choroiditis And Panuveitis
- Punctate Inner Choroidopathy
- Acute Retinal Pigment Epitheliitis
- Acute Posterior Multifocal Placoid Pigment Epitheliopathy
- Subretinal Fibrosis and Uveitis Syndrome
- Acute Zonal Occult Outer Retinopathy and the Azoor Complex Diseases
- Relentless Placoid Choroiditis, Ampiginous Choroiditis, And Persistent Placoid Maculopathy
- One Disease Or Several?
- 31. Masquerade Syndromes
- Intraocular Lymphoma
- Uveal Lymphoma
- Other Malignant Processes Manifesting As Uveitis
- Paraneoplastic Syndromes
- Multiple Sclerosis
- Other Nonmalignant Conditions
- Appendix. Sample Uveitis Questionnaire
- Index
- Edition: 5
- Published: March 31, 2021
- Imprint: Elsevier
- No. of pages: 460
- Language: English
- Hardback ISBN: 9780323480147
- eBook ISBN: 9780323789592
SW
Scott M. Whitcup
Affiliations and expertise
Founder and CEO Akrivista and Whitecap Biosciences, Irvine, California; Clinical Faculty, UCLA Stein Eye Institute, David Geffen School of Medicine at UCLA, Los Angeles, California.Read Whitcup and Nussenblatt's Uveitis on ScienceDirect