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Weedon's Skin Pathology
- 6th Edition - September 18, 2024
- Author: James W. Patterson
- Language: English
- Hardback ISBN:9 7 8 - 0 - 3 2 3 - 9 3 5 5 0 - 0
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 3 5 7 6 - 0
Cutaneous biopsies and excisions constitute the most frequently performed procedures in surgical pathology, yet they present some of the most difficult diagnostic challenges.… Read more
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Request a sales quoteCutaneous biopsies and excisions constitute the most frequently performed procedures in surgical pathology, yet they present some of the most difficult diagnostic challenges. Through five authoritative editions, Weedon's Skin Pathology has earned outstanding reviews and accolades from practicing and trainee dermatopathologists, general pathologists, and dermatologists worldwide. The 6th Edition continues this tradition of excellence, helping you accurately and efficiently sign out complex skin cases in everyday practice, while also keeping you up to date with recent advances in the field. Dr. James W. Patterson’s single-author approach continues to provide clarity and consistency from cover to cover, resulting in what has been described as “the best reference text available in dermatopathology in the world” (Pathology).
- Provides comprehensive coverage of the full spectrum of dermatopathological entities, both inflammatory and neoplastic, highlighted by more than 1,800 color photomicrographs that illustrate the full range of pathologic appearances and help identify each diagnostic entity.
- Helps you arrive at the most accurate diagnoses possible by demonstrating what is seen through the microscope and identifying the characteristic features of the lesion—for established disorders, unusual and rare disease entities, and incompletely defined entities.
- Includes new information on molecular diagnostics throughout, including FISH (fluorescence in situ hybridization) techniques, plus new developments in molecular biology and molecular techniques, targeted-personalized medicine, and immunohistochemistry.
- Contains more tables for quick reference, new figures that demonstrate key differential diagnostic points, and discussions of new entities, as well as thorough content updates in every section.
- Includes practical advice on diagnostic pitfalls and how to avoid them to help minimize reporting errors, and diagnostic clues to assist both experienced and novice practitioners in formulating an accurate diagnosis.
- Identifies both important articles and more rare and unusual reports with remarkably authoritative, comprehensive, current, and relevant reference lists (over 35,000) for each entity.
- An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date.
Dermatopathologists in clinical practice and in training
- Cover image
- Title page
- Table of Contents
- Copyright
- DEDICATION
- Preface
- Section 1. Introduction
- Chapter 1. What’s new in the sixth edition
- Chapter 4: The lichenoid reaction pattern (“interface dermatitis”)
- Chapter 5: The psoriasiform reaction pattern
- Chapter 6: The spongiotic reaction pattern
- Chapter 7: The vesiculobullous reaction pattern
- Chapter 8: The granulomatous reaction pattern
- Chapter 9: The vasculopathic reaction pattern
- Chapter 10: Disorders of epidermal maturation and keratinization
- Chapter 11: Disorders of pigmentation
- Chapter 12: Disorders of collagen
- Chapter 13: Disorders of elastic tissue
- Chapter 14: Cutaneous mucinoses
- Chapter 15: Cutaneous deposits
- Chapter 16: Diseases of cutaneous appendages
- Chapter 17: Cysts, sinuses, and pits
- Chapter 18: Panniculitis
- Chapter 19: Metabolic and storage diseases
- Chapter 21: Cutaneous drug reactions
- Chapter 22: Reactions to physical agents
- Chapter 24: Bacterial and rickettsial infections
- Chapter 25: Spirochetal infections
- Chapter 26: Mycoses and algal infections
- Chapter 27: Viral diseases
- Chapter 28: Protozoal infections
- Chapter 29: Marine injuries
- Chapter 30: Helminth infestations
- Chapter 31: Arthropod-induced diseases
- Chapter 32: Tumors of the epidermis
- Chapter 33: Lentigines, nevi, and melanomas
- Chapter 34: Tumors of cutaneous appendages
- Chapter 35: Tumors and tumor-like proliferations of fibrous and related tissues
- Chapter 36: Tumors of fat
- Chapter 37: Tumors of muscle, cartilage, and bone
- Chapter 38: Neural and neuroendocrine tumors
- Chapter 39: Vascular tumors
- Chapter 40: Cutaneous metastases
- Chapter 41: Cutaneous infiltrates—nonlymphoid
- Chapter 42: Cutaneous infiltrates—lymphomatous and leukemic
- Chapter 2. An approach to the interpretation of skin biopsies
- Introduction
- Major tissue reaction patterns
- Minor tissue reaction patterns
- Patterns of inflammation
- Chapter 3. Diagnostic clues
- Features of particular processes
- Histological features—what do they suggest?
- Clues to a particular disease
- General helpful hints and cautions
- Section 2. Tissue reaction patterns
- Chapter 4. The lichenoid reaction pattern (“interface dermatitis”)
- Introduction
- Lichenoid (Interface) Dermatoses
- Poikilodermas
- Other Lichenoid (Interface) Diseases
- Chapter 5. The psoriasiform reaction pattern
- Introduction
- Major psoriasiform dermatoses
- Other psoriasiform dermatoses
- Chapter 6. The spongiotic reaction pattern
- Introduction
- Neutrophilic spongiosis
- Eosinophilic spongiosis
- Miliarial spongiosis
- Follicular spongiosis
- Pityriasiform spongiosis
- Other spongiotic disorders
- Chapter 7. The vesiculobullous reaction pattern
- Introduction
- Intracorneal and Subcorneal Blisters
- Intraepidermal Blisters
- Suprabasilar Blisters
- Subepidermal Blisters—A Classification
- Subepidermal Blisters with Little Inflammation
- Subepidermal Blisters with Lymphocytes
- Subepidermal Blisters with Eosinophils
- Subepidermal Blisters with Neutrophils
- Subepidermal Blisters with Mast Cells
- Miscellaneous Blistering Diseases
- Chapter 8. The granulomatous reaction pattern
- Introduction
- Sarcoidal granulomas
- Tuberculoid granulomas
- Necrobiotic (collagenolytic) granulomas
- Suppurative granulomas
- Foreign body granulomas
- Xanthogranulomas
- Miscellaneous granulomas
- Lichenoid and granulomatous dermatitis
- Chapter 9. The vasculopathic reaction pattern
- Introduction
- Noninflammatory purpuras
- Vascular occlusive diseases
- Other vascular occlusive diseases
- Urticarias
- Acute vasculitis
- Neutrophilic dermatoses
- Chronic lymphocytic vasculitis
- Vasculitis with granulomatosis
- Miscellaneous vascular disorders
- Section 3. The epidermis
- Chapter 10. Disorders of epidermal maturation and keratinization
- Introduction
- Ichthyoses
- Palmoplantar keratodermas and related conditions
- Cornoid lamellation
- Epidermolytic hyperkeratosis
- Acantholytic dyskeratosis
- Hypergranulotic dyscornification
- Colloid keratosis
- Discrete keratotic lesions
- Miscellaneous epidermal genodermatoses
- Miscellaneous disorders
- Chapter 11. Disorders of pigmentation
- Introduction
- Disorders characterized by hypopigmentation
- Disorders characterized by hyperpigmentation
- Section 4. The dermis and subcutis
- Chapter 12. Disorders of collagen
- Introduction
- Scleroderma
- Sclerodermoid disorders
- Other hypertrophic collagenoses
- Atrophic collagenoses
- Perforating collagenoses
- Variable collagen changes
- Syndromes of premature aging
- Chapter 13. Disorders of elastic tissue
- Introduction
- Increased elastic tissue
- Solar elastotic syndromes
- Decreased elastic tissue
- Variable or minor elastic tissue changes
- Chapter 14. Cutaneous mucinoses
- Introduction
- Dermal mucinoses
- Follicular mucinoses
- Epithelial mucinoses
- Mucopolysaccharidoses
- Chapter 15. Cutaneous deposits
- Introduction
- Calcium, bone, and cartilage
- Hyaline deposits
- Pigment and related deposits
- Cutaneous implants
- Miscellaneous deposits
- Chapter 16. Diseases of cutaneous appendages
- Introduction
- Inflammatory diseases of the pilosebaceous apparatus
- Hair shaft abnormalities
- Alopecias
- Miscellaneous disorders
- Chapter 17. Cysts, sinuses, and pits
- Introduction
- Appendageal cysts
- Developmental cysts
- Miscellaneous cysts
- Lymphatic cysts
- Sinuses
- Pits
- Chapter 18. Panniculitis
- Introduction
- Septal panniculitis
- Lobular panniculitis
- Panniculitis secondary to large vessel vasculitis
- Section 5. The skin in systemic and miscellaneous diseases
- Chapter 19. Metabolic and storage diseases
- Introduction
- Vitamin and dietary disturbances
- Lysosomal storage diseases
- Necrolytic erythemas
- Miscellaneous metabolic and systemic diseases
- Chapter 20. Miscellaneous conditions
- Accessory tragus
- Supernumerary nipple
- Accessory scrotum
- Ectopic tissues
- Cheilitis glandularis
- Umbilical lesions
- Relapsing polychondritis
- Acanthosis nigricans
- Confluent and reticulated papillomatosis
- Acrokeratosis paraneoplastica
- Erythroderma
- Papuloerythroderma
- Scalp dysesthesia
- Cutaneous emphysema
- Chapter 21. Cutaneous drug reactions
- Introduction
- Clinicopathological reactions
- Offending drugs
- Chapter 22. Reactions to physical agents
- Introduction
- Reactions to trauma and irritation
- Reactions to radiation
- Reactions to heat and cold
- Reactions to light (photodermatoses)
- Section 6. Infections and infestations
- Chapter 23. Cutaneous infections and infestations—histological patterns
- Histological patterns in infections and infestations
- Chapter 24. Bacterial and rickettsial infections
- Introduction
- Superficial pyogenic infections
- Deep pyogenic infections (cellulitis)
- Corynebacterial infections
- Neisserial infections
- Mycobacterial infections
- Miscellaneous bacterial infections
- Chlamydial infections
- Rickettsial infections
- Chapter 25. Spirochetal infections
- Introduction
- Treponematoses
- Borrelioses
- Chapter 26. Mycoses and algal infections
- Introduction
- Superficial filamentous infections
- Mycetoma and morphologically mimilar conditions
- Zygomycoses
- Miscellaneous mycoses
- Algal infections
- Chapter 27. Viral diseases
- Introduction
- Poxviridae
- Herpesviridae
- Cytomegalovirus
- Papovaviridae (papillomaviridae)
- Parvoviridae
- Picornaviridae
- Togaviridae
- Flaviviridae
- Paramyxoviridae
- Retroviridae
- Coronaviridae
- Other viral diseases
- Chapter 28. Protozoal infections
- Introduction
- Amebae
- Flagellates
- Coccidia
- Sporozoa
- Miscellaneous
- Chapter 29. Marine injuries
- Introduction
- Cnidarians
- Mollusks
- Echinoderms
- Sponges
- Seaweed
- Venomous Fish
- Chapter 30. Helminth infestations
- Introduction
- Trematode infestations
- Cestode infestations
- Nematode infestations
- Chapter 31. Arthropod-induced diseases
- Introduction
- Arachnids
- Insects
- Section 7. Tumors
- Chapter 32. Tumors of the epidermis
- Introduction
- Epidermal and other nevi
- Pseudoepitheliomatous hyperplasia
- Acanthomas
- Epidermal dysplasias
- Intraepidermal carcinomas
- Malignant tumors
- Miscellaneous “tumors”
- Onycholemmal carcinoma
- 33. Lentigines, nevi, and melanomas
- Introduction
- Lesions with basal melanocyte proliferation
- Melanocytic nevi
- Atypical nevomelanocytic lesions
- Spitz tumors
- Dermal melanocytic lesions
- Melanoma
- Miscellaneous melanocytic and melanocytic-like lesions
- 34. Tumors of cutaneous appendages
- Introduction
- Cutaneous oncocytoma (periocular oncocytoma)
- Hair follicle tumors
- Nevoid follicular lesions
- Benign nongerminative follicular neoplasms
- Benign follicular neoplasms with germinative-type differentiation
- Neoplasms with differentiation toward follicular mesenchyme
- Malignant pilar neoplasms
- Sebaceous tumors
- Pseudoneoplastic sebaceous proliferations
- Benign sebaceous tumors
- Tumors with focal sebaceous differentiation
- Malignant sebaceous tumors
- Sweat gland tumors
- Nevi and malformations of sweat glands
- Benign sweat gland tumors
- Tumors of modified apocrine glands
- Complex adnexal tumors
- Malignant sweat gland tumors
- Adnexal carcinomas with benign counterparts
- Adnexal carcinomas with distinctive features
- Other sweat gland carcinomas
- Chapter 35. Tumors and tumor-like proliferations of fibrous and related tissues
- Introduction
- Acral angiofibromas
- Fibrous overgrowths, fibromatoses, myofibroblastic proliferations, and fibrosarcoma
- Fibrohistiocytic tumors
- Tendon sheath tumors
- Miscellaneous entities
- Chapter 36. Tumors of fat
- Benign lipomatous lesions
- Atypical lipomatous tumors335–338
- Malignant lipomatous tumors
- Chapter 37. Tumors of muscle, cartilage, and bone
- Tumors of smooth muscle
- Tumors of striated muscle
- Tumors of cartilage
- Tumors of bone
- Chapter 38. Neural and neuroendocrine tumors
- Introduction
- Nerve sheath tumors
- Herniations and ectopias
- Neuroendocrine tumors
- Chapter 39. Vascular tumors
- Introduction
- Hamartomas and malformations
- Vascular dilatations (telangiectases)
- Vascular proliferations (hyperplasias and benign neoplasms)
- Tumors with variable or uncertain behavior
- Malignant tumors
- Tumors with a significant vascular component
- Chapter 40. Cutaneous metastases
- Introduction
- Clinical and morphological features
- Specific metastases
- Chapter 41. Cutaneous infiltrates—nonlymphoid
- Introduction
- Neutrophil infiltrates
- Eosinophil infiltrates
- Plasma cell infiltrates
- Mast cell infiltrates
- Histiocytic infiltrates (nonLangerhans cell)
- Xanthomatous infiltrates
- Langerhans cell infiltrates
- Chapter 42. Cutaneous infiltrates—lymphomatous and leukemic
- Introduction
- Cutaneous T-Cell and NK-Cell Lymphomas
- Cutaneous B-Cell Lymphomas
- Precursor Hematological Neoplasm
- Secondary cutaneous involvement in T-Cell lymphomas and leukemias
- Other B-Cell lymphomas that may involve the skin
- Other lymphomas
- Cutaneous infiltrates of leukemias
- Lymphoid hyperplasias mimicking primary lymphoma
- Miscellaneous
- INDEX
- No. of pages: 1376
- Language: English
- Edition: 6
- Published: September 18, 2024
- Imprint: Elsevier
- Hardback ISBN: 9780323935500
- eBook ISBN: 9780323935760
JP
James W. Patterson
Dr Jim Patterson has been recognized as an outstanding teacher, practitioner, and mentor by many physician trainees in Dermatopathology, Dermatology, and Pathology. His knowledge and experience in clinical dermatology, combined with his outstanding skills in histopathology, have made him an internationally recognized authority who has contributed substantially to the field of dermatopathology. Areas of special interest include differential diagnosis in dermatopathology, inflammatory skin disease, panniculitis, malignant melanoma, cutaneous T- cell lymphoma and other cutaneous malignancies, opportunistic infections, and immunofluorescence studies.
Affiliations and expertise
Professor Emeritus of Pathology, University of Virginia Health System, Charlottesville, VA, USA