Water and Hydration in Health and Disease Prevention
- 1st Edition - June 1, 2027
- Latest edition
- Editors: Rajkumar Rajendram, Vinood B. Patel, Victor R. Preedy
- Language: English
Water is one of the most fundamental needs sustaining human life. In the human body, hydration allows for the balance of electrolytes and the functioning of the kidneys,… Read more
Description
Description
Key features
Key features
- Complies interdisciplinary knowledge of water supply, use, nutrition, physiology, and environmental factors
- Identifies therapeutic benefits of water as a nutraceutical or performance enhancer
- Covers the most important aspects of water in health and disease
Readership
Readership
Table of contents
Table of contents
Section I. Introductory chapters and setting the scene
1. Guidelines for water intake
2. Hydration and metabolic health: a new narrative
3. An overview of the regulation of water balance in the body
Section II. Physiological variables
4. Psychobiology of thirst: an updated narrative
5. The vasopressin system and regulation of water balance
6. Sodium and water balance
7. Preventing dehydration: Aldosterone and regulation of water balance
8. Preventing dehydration: Renin-Angiotensin system and water regulation
9. Overconsumption of hypotonic fluids: Preventing hyponatremia due to exercise
10. Prevention of delayed symptomatic hyponatremia in surgery
Section III. Cellular and molecular variables
11. Vasopressin system and thirst
12. Osmoreceptors and the control of water balance
13. Cellular and molecular processes: Osmolytes
14. Cellular and molecular processes: Baroreceptors
15. Cellular and molecular processes: Aquaporin
Section IV. Regulation of water intake
16. Regulation of water intake by cannabinoids: CB1 receptors and the insular cortex
17. Brain and control of water intake: linking the paraventricular hypothalamic nucleus
18. Vasopressin and regulation of fluid balance in pregnancy
Section V. Thirst, dehydration, and reduced water intake
19. Definitions: dehydration and underhydration in acute and chronic scenarios
20. The inhibitory mechanisms that control thirst and satiety
21. Thirst in heart failure
22. Deliberate dehydration in sports
23. Dehydration in cholera
Section VI. Water as a nutritional vehicle, sports and energy drinks
24. Hydrogen-rich water intake and effects on human biology
25. Energy drinks consumed by adolescents
26. Popular and new isotonic sports drinks
27. Energy drinks consumed with alcohol
28. Isomaltulose in sports drinks
29. Energy drinks and effects on brachial artery: measures of endothelial functions
30. Hydration with sugar-sweetened beverages
Section VII. Mineral Water
31. Contaminants in mineral water
32. Profiles of bottled mineral waters
33. Mineral waters and modulation of intestinal inflammation
34. Bicarbonate-rich mineral water
35. Iron-rich mineral water as an adverse scenario
Section VIII. Tap and drinking water
36. Global warming and impact on water supplies
37. Phthalates in drinking water
38. Lead-in drinking water
39. Adverse scenarios of tap water linked with reduced cognition
40. Fluoride in drinking water and health consequences
Section IX. Drinking water and intake in different scenarios
41. Improving water intake in sports (football)
42. Menopause and water intake wrinkles and beyond
43. Water intake and menstrual distress
44. Water intake and water insecurity
45. Drinking water and intake in pregnancy: health and disease prevention (arsenic)
46. Hypovolemia in the elderly
Section X. Clinical Scenarios
i. Hyponatremic conditions
47. Water loading and acute hyponatremia
48. Hyponatremia and Psychogenic Polydipsia
ii. Hypovolemic conditions
49. Hypovolemic shock in trauma
50. Prediction and diagnosis of hypovolemic
iii. Diuretics
51. Diuretics and hyponatremia
52. Diuretics use in critically ill patients
iv. Water intake
53. Water intake and effects on copeptin in diabetes
54. Water, hydration and cognition
55. Linking water intake and BMI
v. Conditions and disease
56. Fluid balance in diabetes insipidus
57. Polydipsia
58. Fluid balance in chronic kidney disease
59. Fluid balance in polycystic kidney disease
60. Fluid balance in cardiovascular diseases
61. Water, hydration and cognition
Section XI. Risks and effects of contaminations
62. Perfluoroalkyl substances (PFASs) in water and risks of consumption
63. Drinking water and environmental risk: radioactivity
64. Nitrates in drinking water and FOXE1 polymorphisms
65. Risks and effects of contaminations: hormones
66. Risks and effects of contaminations: pharmaceuticals
67. Risks and effects of contaminations: heavy metals
Section XII. Resources
68. Resources in Water and Hydration in Health and Disease Prevention
Product details
Product details
- Edition: 1
- Latest edition
- Published: June 1, 2027
- Language: English
About the editors
About the editors
Rajkumar Rajendram
Dr Rajkumar Rajendram is a clinician-scientist with expertise in internal medicine, anaesthesia, intensive care and peri-operative medicine. He graduated with distinctions from Guy’s, King’s and St Thomas’ Medical School, King’s College London, in 2001, where he received several prizes, merits and distinctions in pre-clinical and clinical subjects.
Dr Rajendram completed specialist training in acute and general medicine in Oxford and subsequently held a Consultant appointment in Acute General Medicine at the John Radcliffe Hospital, Oxford. He also trained in anaesthesia and intensive care in London, including advanced training in regional anaesthesia and intensive care, and subsequently held a Consultant appointment in Intensive Care, Anaesthesia and Peri-operative Medicine at the Royal Free London Hospitals.
His postgraduate training has spanned internal medicine, anaesthesia, intensive care and point-of-care ultrasound (POCUS). He was awarded Fellowship of the Royal College of Anaesthetists in 2009, Fellowship of the Faculty of Intensive Care Medicine in 2013, and the European Diploma in Intensive Care Medicine in 2014. He is a Fellow of both the Royal College of Physicians of Edinburgh and the Royal College of Physicians of London.
Dr Rajendram is currently a Consultant at King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia, and holds a joint appointment as Associate Professor in the Research Unit, Department of Medical Education, at King Saud bin Abdulaziz University for Health Sciences.
His multidisciplinary clinical background has informed his research interests in nutrition, fluid management and fluid balance in health and disease, particularly in acutely and critically ill patients. His research has also addressed POCUS, COVID-19 phenotypes and nutritional support in illness. Dr Rajendram has contributed extensively to medical research and education and has authored more than 400 textbook chapters, review articles, peer-reviewed papers and conference abstracts.
Vinood B. Patel
Vinood B. Patel, BSc, PhD, FRSC, is Professor in Clinical Biochemistry at the University of Westminster. In 2014 Dr Patel was elected as a Fellow to The Royal Society of Chemistry. Dr Patel graduated from the University of Portsmouth with a degree in Pharmacology and completed his PhD in protein metabolism from King’s College London in 1997. His postdoctoral work was carried out at Wake Forest University Baptist Medical School, NC, USA studying structural-functional alterations to mitochondrial ribosomes, where he developed novel techniques to characterize their biophysical properties. Research is being undertaken to study the role of nutrients, antioxidants, phytochemicals, iron, alcohol and fatty acids in the pathophysiology of disease. Other areas of interest are identifying new biomarkers that can be used for the diagnosis and prognosis of disease and understanding mitochondrial oxidative stress. Dr Patel is a nationally and internationally recognized researcher and has several edited biomedical books related to health and well being These books include Ancient and traditional foods, plants and herbs and spices in human health; coffee in health and disease prevention, Nuts and seeds in health and disease prevention Handbook of Substance Misuse and Addictions: From Biology to Public Health, tea in health and disease prevention.
Victor R. Preedy
Victor R. Preedy, BSc, PhD, DSc, FRSB, FRSPH, FRCPath, FRSC, FRSM, is Professor of Clinical Biochemistry (Hon) at King’s College Hospital and Emeritus Professor of Nutritional Biochemistry at King’s College London. He also holds an Honorary Professorship at the University of Suffolk and served as the long‑term Director of the Genomics Centre at King’s College London from 2006 to 2020. Professor Preedy graduated with an Honours Degree in Biology and Physiology with Pharmacology and later obtained his PhD from the University of London. He subsequently received Membership of the Royal College of Pathologists and later earned his second doctorate (DSc) in recognition of his contributions to protein metabolism. He is a Fellow of the Royal Society of Medicine, the Royal Society of Biology, the Royal College of Pathologists, the Royal Society for the Promotion of Health, the Royal Institute of Public Health and Hygiene, the Royal Society for Public Health, and the Royal Society of Chemistry. Professor Preedy has conducted research while affiliated with Imperial College London, the School of Pharmacy (now part of University College London), and the MRC Centre at Northwick Park Hospital. He has collaborated widely with international research groups in Finland, Japan, Australia, the USA, and Germany. His longstanding academic interests include health and well‑being. He has published more than 750 works, including peer‑reviewed research articles, abstracts, symposium presentations, reviews, and edited books.