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Vagus Nerve

From Homeostatic Regulations to Disease Etiopathogenesis, Treatment, and Prevention

  • 1st Edition - May 1, 2027
  • Latest edition
  • Author: Boris Mravec
  • Language: English

Vagus Nerve: From Homeostatic Regulations to Disease Etiopathogenesis, Treatment, and Prevention is a comprehensive reference that encapsulates every critical aspect of the vagus… Read more

Description

Vagus Nerve: From Homeostatic Regulations to Disease Etiopathogenesis, Treatment, and Prevention is a comprehensive reference that encapsulates every critical aspect of the vagus nerve, tracing its anatomy, phylogeny, and physiology while exploring its pivotal role in both maintaining homeostasis and the development of various diseases. This groundbreaking work details the potential of vagus nerve stimulation as a therapeutic and preventive measure for a wide range of conditions, including neurological, psychiatric, inflammatory, cardiovascular, and gastrointestinal disorders. This book demystifies the mechanisms of vagus nerve function and its implications for health and disease. Each section delves into the historical context of vagus nerve research, its anatomical and functional characteristics, and its regulatory roles across multiple organ systems. Additionally, the book investigates the etiopathogenesis of diseases linked to vagus nerve dysfunction and outlines experimental methods for investigating its functions. With a focus on prognosis and therapy, this book highlights the prognostic value of vagus nerve activity and explores various therapeutic modalities that influence it. Concluding with directions for future research, this essential resource aims to foster a deeper understanding of the vagus nerve's significance in health and disease, opening new avenues for therapeutic innovation and clinical application.

Key features

  • Identifies specific disorders and conditions associated with vagus nerve dysfunction, providing a detailed look at their clinical implication
  • Discusses the implications of vagus nerve activity on mental health, including its influence on stress, anxiety, and emotional regulation
  • Presents innovative experimental techniques and methodologies for investigating vagus nerve functions, facilitating advanced research applications
  • Explores the interplay between the vagus nerve and lifestyle factors, such as diet, exercise, and stress management, and their impact on overall health

Readership

Researchers, physicians and advanced graduate students in neuroscience and neurology

Table of contents

Part I. History and present of research on the nervus vagus

1. Anatomical description and nomenclature of the cranial nerves: From Galen to Von Soemmerring

2. The importance of the nervus vagus in the regulation of bodily functions: from Langley to Loewi

3. The vagus nerve and inflammation: From Watkins to Tracey

4. The vagus nerve and stress: from stress response to emotion

5. The vagus nerve and cancer: from Gidron to the neurobiology of cancer

Part II. Anatomical and functional characteristics of the nervus vagus

6. Anatomical features of the nervus vagus

7. Motor functions of the nervus vagus

8. Sensory functions of the nervus vagus

9. Phylogeny of the nervus vagus

10. Ontogeny of the nervus vagus

Part III. Regulation of organ, tissue and cellular functions

11. Homeostasis, allostasis and the nervus vagus

12. The role of the nervus vagus in reflex and defensive reactions

13. The immune system, the cholinergic anti-inflammatory pathway and the inflammatory reflex

14. Cardiovascular system

15. Respiratory system

16. Gastrointestinal system

17. Uropoietic system

18. Reproductive system

19. Endocrine system

20. Regulation of water intake, food intake and metabolism

21. Nervus vagus and the stress response

22. The vagus nerve and emotions

23. Central nervous system

24. Circadian rhythms and the nervus vagus

Part IV. Etiopathogenesis of diseases and the nervus vagus

25. Inflammatory diseases

26. Autoimmune diseases

27. Cardiovascular diseases

28. Respiratory diseases

29. Gastrointestinal diseases

30. Metabolic diseases

31. Diseases of the uropoietic system

32. Reproductive diseases

33. Cancer

34. Neurological diseases

35. Psychiatric disorders

36. Ageing and function of the nervus vagus

37. Selected clinical conditions associated with disruption of vagal innervation

38. Tissue lesions of the nervus vagus

Part V. Methods of experimental investigation of the functions of the nervus vagus

39. Stimulation methods

40. Vagotomy

41. Other methods

Part VI. Nervus vagus in prognosis and therapy of diseases

42. Prognostic value of determination of nervus vagus activity

43. Therapeutic modalities affecting the activity of the nervus vagus

Part VII. Directions for further research into the functions of the nervus vagus

44. Unanswered questions

45. Future research directions

Product details

  • Edition: 1
  • Latest edition
  • Published: May 1, 2027
  • Language: English

About the author

BM

Boris Mravec

Boris Mravec, PhD, is a Lecturer at the Faculty of Medicine of the Comenius University in Bratislava. His research investigates the role of stress and neuro-endocrine-immune interactions in the etiopathogenesis of somatic diseases, focusing on the role of the vagus nerve.

Affiliations and expertise
Professor of Normal and Pathological Physiology at the Institute of Physiology, Faculty of Medicine, Comenius University in Bratislava, Slovak Republic