Use of Biologic and Regenerative Therapies in Equine Practice, An Issue of Veterinary Clinics of North America: Equine Practice
- 1st Edition, Volume 39-3 - October 30, 2023
- Editor: Lauren V. Schnabel
- Language: English
- Hardback ISBN:9 7 8 - 0 - 3 2 3 - 9 3 8 9 1 - 4
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 3 8 9 2 - 1
In this issue of Veterinary Clinics of North America: Equine Practice, guest editor Ds. Lauren V. Schnabel brings her considerable expertise to the topic of Use of Biologic and… Read more
Purchase options
Institutional subscription on ScienceDirect
Request a sales quoteIn this issue of Veterinary Clinics of North America: Equine Practice, guest editor Ds. Lauren V. Schnabel brings her considerable expertise to the topic of Use of Biologic and Regenerative Therapies in Equine Practice. Top experts in the field explain what the main biologic and regenerative therapies are, what they contain, evidence to date for how they should be used, and how to monitor response to treatment. While the majority of the issue will focus on musculoskeletal applications, other indications for use will be discussed including wounds and ophthalmologic conditions as well as other inflammatory diseases.
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Forthcoming Issues
- Preface
- Dedications
- Introduction to Equine Biologic and Regenerative Therapies
- Key points
- Introduction to equine biologic and regenerative therapies
- Minimally processed blood-derived orthobiologics
- Tissue-derived orthobiologics: minimally manipulated and culture expanded
- Stem cell therapy: cellular concentrates
- Stem cell therapy: culture expansion
- Summary
- Disclosure
- Equine Platelet-Rich Plasma
- Key points
- Introduction
- Rationale and definitions
- Clinical use of platelet-rich plasma
- Platelet activation
- Concurrent nonsteroidal anti-inflammatory therapy
- Complications
- Future directions
- Summary
- Clinics care points
- Disclosure
- Equine Autologous Conditioned Serum and Autologous Protein Solution
- Key points
- Introduction
- Autologous conditioned serum
- Autologous protein solution
- Summary
- Disclosure
- Equine Bone Marrow Aspirate Concentrate
- Key points
- Introduction
- Generation of BMC
- The cells in BMC
- Biophysical and biochemical signals
- Clinical applications of BMC
- Summary
- Clinics care points
- Disclosure
- Overview of Equine Stem Cells: Sources, Practices, and Potential Safety Concerns
- Key points
- Introduction
- Equine stem cell sources
- Equine stem cell practices
- Potential safety concerns
- Clinics care points
- Disclosure
- Funding
- Use of Stem Cells for the Treatment of Musculoskeletal Injuries in Horses
- Key points
- Introduction
- Discussion
- Summary
- Clinics care points
- Disclosures
- Advances in Imaging Techniques to Guide Therapies and Monitor Response to the Treatment of Musculoskeletal Injuries
- Key points
- Introduction
- Diagnostic imaging modalities
- Clinics care points
- Conflict of interest
- Disclosure
- Advances in Regional Vascular Injection Techniques for the Delivery of Stem Cells to Musculoskeletal Injury Sites
- Key points
- Introduction
- Comparison of different regional vascular injection techniques
- Technical aspects of intra-arterial injections in standing horses
- Clinical applications
- Summary
- Clinics care points
- Interactions Between Biologic Therapies and Other Treatment Modalities
- Key points
- Introduction
- Discussion
- Summary
- Disclosure
- Clinics care points
- Use of Biologics and Stem Cells for Wound Healing in the Horse
- Key points
- Background
- Evidence for the efficacy of biologic therapies for equine skin wounds
- Future directions
- Summary
- Clinics care points
- Disclosure
- Use of Biologics and Stem Cells in Equine Ophthalmology
- Key points
- Introduction
- Corneal ulceration
- Immune-mediated keratitis
- Uveitis and ocular posterior segment disease
- Retinal detachment
- Summary
- Clinics care points
- Disclosure
- Use of Biologics and Stem Cells in the Treatment of Other Inflammatory Diseases in the Horse
- Key points
- Mesenchymal stem cells modulate the immune system
- How mesenchymal stem cells modulate the immune system
- Endotoxemia in the horse
- Recurrent airway obstruction in the horse
- Gastrointestinal system and mesenchymal stem cells
- Mesenchymal stem cell treatment of laminitis in the horse
- Summary
- Clinics care points
- Disclosure
- Antimicrobial Properties of Equine Stromal Cells and Platelets and Future Directions
- Key points
- Summary
- Evidence for antimicrobial properties of equine mesenchymal stromal cells
- Methods to enhance antimicrobial properties of mesenchymal stromal cells
- Future directions with microcapsules and exosome-based therapies
- Potential applications and challenges with mesenchymal stromal cells in equine practice
- Evidence for antimicrobial properties of equine platelet products
- Methods to enhance antimicrobial properties of equine platelet products
- Potential applications and challenges with platelet lysate products in equine practice
- Summary
- Clinics care points
- Conflicts of interest
- No. of pages: 240
- Language: English
- Edition: 1
- Volume: 39-3
- Published: October 30, 2023
- Imprint: Elsevier
- Hardback ISBN: 9780323938914
- eBook ISBN: 9780323938921
LS
Lauren V. Schnabel
Affiliations and expertise
Diplomate ACVS (LA), Diplomate ACVSMR (Equine), North Carolina State University College of Veterinary Medicine , Department of Clinical Sciences