
Update on Obesity, An Issue of Endocrinology and Metabolism Clinics of North America
- 1st Edition, Volume 54-1 - February 11, 2025
- Imprint: Elsevier
- Editors: Caroline M. Apovian, Dong Wook Kim
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 3 - 3 1 6 3 2 - 6
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 3 1 6 3 3 - 3
In this issue of Endocrinology and Metabolism Clinics, guest editors Drs. Caroline M. Apovian and Dong Wook Kim bring their considerable expertise to the topic of Update on Obesit… Read more

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Request a sales quoteIn this issue of Endocrinology and Metabolism Clinics, guest editors Drs. Caroline M. Apovian and Dong Wook Kim bring their considerable expertise to the topic of Update on Obesity. Top experts in the field cover the latest research regarding weight loss drugs, drug safety, pharmacotherapy, AI, and nutritional/lifestyle changes for managing obesity.
- Contains 15 relevant, practice-oriented topics including drug safety and pharmacovigilance of anti-obesity medications; obesity stigma; non-pharmacological treatment for obesity; artificial intelligence and obesity management; intermittent fasting and obesity; and more
- Provides in-depth clinical reviews on obesity, offering actionable insights for clinical practice
- Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews
Endocrinologists
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Forthcoming Issues
- Foreword
- Preface
- The American Board of Obesity Medicine: A Pathway to Provision of Competent Obesity Medicine Care
- Key points
- Background
- Obesity medicine board certification
- Discussion
- Summary
- Clinics care points
- Weight Stigma
- Key points
- Background
- Discussion
- Compassionate and bias-free approach to patient care for obesity
- Summary
- Clinics care points
- Disclosures
- Declaration of AI and AI-assisted technologies in the writing process
- Management of Obesity-Related Genetic Disorders
- Key points
- Introduction
- Monogenic obesity and the importance of leptin-melanocortin signaling
- Syndromic obesity
- Current approach
- Summary
- Clinics care points
- Management of Adolescent Obesity
- Key points
- Introduction
- Etiology
- Assessment and diagnosis of obesity in adolescents
- Treatment
- Summary
- Clinics care points
- Intermittent Fasting: Implications for Obesity-Related Colorectal Tumorigenesis
- Key points
- Introduction
- Results
- Discussion and implications for obesity-related colorectal tumorigenesis
- Future directions
- Summary
- Clinics care points
- Cutting-Edge Approaches to Obesity Management: The Latest Pharmacological Options
- Key points
- Introduction
- Phentermine (Adipex, Lomaira)
- Orlistat (Xenical)
- Phentermine/topiramate Extended Release (Qsymia)
- Bupropion SR/naltrexone SR (Contrave)
- Liraglutide 3.0 mg (Saxenda)
- Semaglutide 2.4 mg (Wegovy)
- Tirzepatide (Zepbound)
- Summary
- Clinics care points
- Nutrient-Stimulating Hormone-Based Therapies for Obesity
- Key points
- Introduction
- Obesity definition
- Clinical approach to obesity management
- Future NuSH-based therapies
- Summary
- Clinics care points
- Disclosures
- Bariatric Surgery: Overview of Procedures and Outcomes
- Key points
- Introduction
- Current surgical bariatric procedures
- Diabetes remission after bariatric surgery
- Clinics care points
- Optimizing Micro and Macro Nutrients: Navigating Weight Loss Success and Health Risks in Bariatric Surgery for Obesity Management
- Key points
- Introduction
- Bariatric surgery
- Laparoscopic sleeve gastrectomy
- Roux-en-Y-gastric bypass procedure
- Bilio-pancreatic diversion duodenal switch
- Adjustable gastric banding
- Pre-operative nutritional considerations and deficiencies
- Post-operative nutritional considerations and deficiencies
- Post-operative macronutrient optimization
- Summary
- Clinics care points
- Endoscopic Weight Loss Options
- Key points
- Introduction
- Gastric endoscopic bariatric and metabolic therapies
- Small bowel endoscopic bariatric and metabolic therapies
- Discussion
- Summary
- Clinics care points
- Treatment of Type 2 Diabetes in Patients with Obesity: A Review
- Key points
- Introduction
- The pathophysiology of glucose intolerance in type 2 diabetes mellitus and obesity
- Goals
- Therapeutic options
- Current evidence
- Patient monitoring, side effects and adverse events
- Challenges
- Discussion
- Summary
- Clinics care points
- The Close Link Between Obesity and Cardiovascular Disease: Current Insights and Remaining Challenges
- Key points
- Introduction
- Plausible mechanism: how does obesity link to cardiovascular disease?
- Impact of obesity on cardiovascular disease: coronary artery disease
- Impact of obesity on cardiovascular disease: heart failure
- Impact of obesity on cardiovascular disease: atrial fibrillation
- Management strategies: non-pharmacological and pharmacologic approach
- Controversies and challenges
- Summary
- Clinics care points
- Exploring the Bidirectional Relationship Between Depression and Obesity
- Key points
- Definition
- Introduction
- Epidemiology
- Healthcare cost of a co-occurrence of depression and obesity
- Neurobiologic mechanism of the co-occurrence of depression and obesity
- Pharmacotherapy
- Summary
- Clinics care points
- The Role of Artificial Intelligence in Obesity Medicine
- Key points
- Introduction
- Artificial intelligence in obesity medicine
- Challenges and ethical considerations
- Summary
- Clinics care points
- Declaration of artificial intelligence and artificial intelligence-assisted technologies in the writing process
- Edition: 1
- Volume: 54-1
- Published: February 11, 2025
- Imprint: Elsevier
- No. of pages: 240
- Language: English
- Hardback ISBN: 9780443316326
- eBook ISBN: 9780443316333
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Caroline M. Apovian
Affiliations and expertise
Co-Director, Center for Weight Management and Wellness, Professor of Medicine, Harvard Medical School Endocrinology, Diabetes and Hypertension Brigham and Women's Hospital, Center for Weight Management and Wellness, Boston, MA, USADK
Dong Wook Kim
Affiliations and expertise
Director, Obesity Medicine Fellowship Program, Center for Weight Management and Wellness, Division of Endocrinology, Diabetes & Hypertension, Brigham and Womens Hospital, Boston, MA, USA