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Treatment and Management of Tropical Liver Disease
- 1st Edition - November 1, 2023
- Editor: Jose Debes
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 8 7 0 3 1 - 3
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 1 9 4 4 - 6
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 8 7 0 3 2 - 0
Offering a unique, comprehensive overview of common and uncommon liver diseases found in the tropics and resource-constrained regions, Treatment and Management of Tropical Liver Di… Read more
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Request a sales quoteOffering a unique, comprehensive overview of common and uncommon liver diseases found in the tropics and resource-constrained regions, Treatment and Management of Tropical Liver Disease provides practical information and insights on both diagnosis and treatment. It offers valuable details on acute and chronic viral and parasitic hepatic infections, bacterial and fungal infections, liver masses, autoimmune diseases, and other liver-related maladies typically found in the tropics. An expert global author team covers making a diagnosis with imaging techniques most likely found in specific regions, offers guidance on managing patients in areas with limited resources once a diagnosis has been established, and discusses how to manage patients with chronic liver disease with a focus on cost-effectiveness and quality of life.
- Includes a summary and tables with specific guidance on the diagnosis and management of each liver disease, enabling you to easily find the information you need.
- Contains a pathophysiology guide in every chapter to help you quickly determine the immune and epigenetic mechanisms that affect common liver diseases when they occur in tropical regions.
- Covers key topics such as liver flukes, tropical hepatosplenomegaly, and much more, all highlighted with ultrasound images, clinical photos, and full-color line drawings.
- Provides guidance on the interpretation and management of liver masses using imaging techniques commonly performed in resource-limited settings.
- Provides a unique, detailed review of essential information for hepatologists, global health specialists, and other clinicians who have an interest in this complex field.
- An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.
Hepatologists, global health specialists, IM specialists treating patients with liver disease contracted in a tropical setting
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- List of Illustrations
- List of Tables
- Section I. Viral Hepatitides
- 1. Hepatitis A
- Introduction
- References
- 2. Hepatitis B virus
- Overview
- Virology
- Clinical presentation
- Treatment
- Complications
- Prevention
- References
- 3. Hepatitis C infection
- Introduction
- Virology
- References
- 4. Hepatitis delta virus
- Introduction
- HDV life cycle
- Epidemiology
- Pathogenesis
- Clinical features and course of HDV infection
- Diagnosis and approach
- Treatment
- References
- 5. Hepatitis E virus
- Introduction
- Virology
- Hepatitis E in special populations
- Prevention of HEV
- References
- Section II. Liver Masses
- 6. Hepatocellular carcinoma
- Introduction
- Epidemiology
- Symptoms
- Screening
- Diagnosis
- Treatment
- HBV-related HCC
- HIV-related HCC
- References
- 7. Cholangiocarcinoma
- Introduction
- Epidemiology
- Clinical presentation
- Diagnosis
- Management
- Targeted therapies for CCA
- References
- 8. Hepatic hemangioma
- Introduction
- Diagnostics
- References
- 9. Other liver masses
- Introduction
- Hepatic cysts
- Focal nodular hyperplasia
- Hepatic adenoma
- Focal fat deposition or sparing
- Biliary hamartomas
- Liver metastases
- Lymphoma
- Hydatid cyst
- References
- Section III. Tropical Infectious Liver Disease
- 10. Schistosomiasis
- Introduction
- Pathogenesis
- Clinical presentation
- Diagnosis of Schistosoma mansoni
- Diagnosis of periportal fibrosis
- Treatment
- Vaccines against schistosomiasis
- References
- 11. Fascioliasis
- Introduction
- Life cycle
- Epidemiology
- Clinical manifestations
- Diagnosis
- Management and prevention
- References
- 12. Opisthorchis and clonorchis
- Introduction
- Epidemiology
- Pathology and pathogenesis
- Clinical presentation
- Diagnosis
- Treatment
- Control of opisthorchiasis and clonorchiasis
- References
- 13. Hepatic tuberculosis
- Introduction
- Pathogenesis
- Epidemiology
- Clinical presentation
- Imaging
- Differential diagnosis
- Diagnosis
- Management
- Complications
- Congenital tuberculosis
- References
- 14. Malaria and the liver
- Epidemiology of malaria
- Life cycle of malaria
- Pathogenesis of malaria
- Clinical features of malaria
- The liver in severe malaria
- The liver in uncomplicated malaria
- The effect of preexisting immunity on liver damage
- References
- 15. HIV and liver disease
- Introduction
- Role of HIV in liver damage
- Hepatitis B virus coinfection
- Hepatitis D and HIV infection
- Hepatitis C virus coinfection
- Alcohol use disorder
- Non-alcoholic steatohepatitis
- Hepatocellular carcinoma
- Herbal medicines
- Autoimmune hepatitis
- Antiretroviral drug–induced liver injury
- Other liver diseases
- Conclusions
- References
- 16. Amebic liver abscess
- Introduction
- References
- 17. Cystic echinococcosis—hydatid liver disease
- Introduction
- Life cycle and natural history
- Epidemiology
- Clinical manifestations
- CE diagnosis
- Clinical management
- Complicated cysts in the abdomen
- References
- Section IV. Tropical Non-Infectious Liver Disease
- 18. Non-cirrhotic portal hypertension
- Introduction
- Extrahepatic portal venous obstruction
- Clinical features
- Investigations
- Natural history
- Treatment
- Non-cirrhotic intrahepatic portal hypertension
- References
- 19. Cirrhosis in the tropics
- Introduction
- Epidemiology
- Presentation
- Diagnosis
- Management of cirrhosis complications
- References
- 20. Metabolic dysfunction associated steatotic liver disease in resource-limited settings
- MASLD epidemiology in Latin America (LATAM) and sub-Saharan Africa (SSA)
- Unique aspects of MASLD in SSA
- Current challenges in addressing the public health problem of MASLD in Latam and SSA as examples of low-resource healthcare settings
- References
- 21. Aflatoxins in liver disease
- Introduction
- Aflatoxins biological effects
- Aflatoxins effects on the liver
- References
- 22. Tropical herb-induced liver injury by pyrrolizidine alkaloids
- Introduction
- Pathogenesis
- Epidemiology
- Diagnostic approaches
- Treatment
- References
- 23. Alcohol-related liver disease
- Introduction
- Epidemiology
- Pathogenesis
- Presentation
- Diagnosis
- Management
- References
- 24. Drug-induced liver injury in tropical settings
- Introduction
- Challenges in DILI presentation and diagnosis
- Specific drug patterns of injury
- Anti-tuberculosis drugs
- Antiretroviral therapy
- Miscellaneous drugs
- Summary
- References
- 25. Congestive hepatopathy
- Introduction
- Pathogenesis
- References
- 26. Acute liver failure
- Introduction
- Etiology of ALF
- References
- 27. Liver transplantation in tropical settings
- Introduction
- Chagas disease
- Malaria
- Leishmaniasis
- Strongyloidiasis
- Schistosomiasis
- Challenges
- Conclusion
- References
- Section V. Rare Tropical Liver Diseases
- 28. Melioidosis and the liver
- Introduction
- References
- 29. Histoplasmosis
- Introduction
- Epidemiology
- References
- 30. Brucellosis and the liver
- Introduction and epidemiology
- Clinical presentation
- Diagnosis
- Brucellosis of the liver
- Treatment
- References
- 31. Leptospirosis and the liver
- Introduction
- Epidemiology
- Etiopathogenesis
- Clinical presentation
- Diagnostic studies
- Management
- References
- 32. The liver in Q fever
- Background
- Historical overview
- Acute Q fever and its impact on the liver
- Diagnosis of acute and chronic Q fever
- Pathophysiology of Q fever hepatitis
- Treatment and prevention
- References
- 33. Hepatic manifestations of the dengue infection
- Introduction
- Clinical presentation
- Dengue and COVID-19
- Pathophysiology of liver injury in dengue
- Acute liver failure in dengue infection
- Diagnosis
- Management
- Conclusion
- References
- 34. Leishmaniasis and the liver
- Global epidemiology
- Clinical features and imaging
- Visceral leishmaniasis and the liver
- Laboratory diagnosis
- Treatment
- References
- 35. Iron overload in sub-Saharan A frica
- Introduction
- Epidemiology
- Presentation
- Diagnosis and management
- Acknowledgment
- References
- Index
- No. of pages: 320
- Language: English
- Edition: 1
- Published: November 1, 2023
- Imprint: Elsevier
- Paperback ISBN: 9780323870313
- eBook ISBN: 9780443119446
- eBook ISBN: 9780323870320
JD
Jose Debes
Affiliations and expertise
Associate Professor, Department of Medicine
University of Minnesota, Minneapolis, MN, USA
Associate Professor, Department of Gastroenterology & HepatologyRead Treatment and Management of Tropical Liver Disease on ScienceDirect