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Translational Medicine: Tools And Techniques
1st Edition - November 24, 2015
Editor: Aamir Shahzad
Paperback ISBN:9780128034606
9 7 8 - 0 - 1 2 - 8 0 3 4 6 0 - 6
eBook ISBN:9780128034941
9 7 8 - 0 - 1 2 - 8 0 3 4 9 4 - 1
Translational Medicine: Tools and Techniques provides a standardized path from basic research to the clinic and brings together various policy and practice issues to simplify the… Read more
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Translational Medicine: Tools and Techniques provides a standardized path from basic research to the clinic and brings together various policy and practice issues to simplify the broad interdisciplinary field. With discussions from academic and industry leaders at international institutions who have successfully implemented translational medicine techniques and tools in various settings, readers will be guided through implementation strategies relevant to their own needs and institutions. The book also addresses regulatory processes in USA, EU, Japan and China. By providing details on omics sciences techniques, biomarkers, data mining and management approaches, case reports from industry, and tools to assess the value of different technologies and techniques, this book is the first to provide a user-friendly go-to guide for key opinion leaders (KOLs), industry administrators, faculty members, clinicians, researchers, and students interested in translational medicine.
Includes detailed and standardized information about the techniques and tools used in translational medicine
Provides specific industry case scenarios
Explains how to use translational medicine tools and techniques to plan and improve infrastructures and capabilities while reducing cost and optimizing resources
practitioners and researchers working in biomedical research, health center administrators, health professions associations, life sciences industry professionals in pharma, biotech, medical instruments, diagnostic companies, CROs, research reagent Suppliers, IT service providers, data management companies, senior to junior level academic faculty members, post graduate students and scholars, public health professionals, regulatory affairs professionals
List of Contributors
About the Editor
Preface
Acknowledgments
Chapter 1. New Developments in the Use of Biomarkers in Translational Medicine
Introduction
Biomarkers as Part of a Translational Strategy
New Types of Biomarkers
New Ways of Analyzing Biomarker Data
Biomarker Documentation
Promising Applications
Conclusions
Chapter 2. Advancements in Data Management and Data Mining Approaches
Introduction
Challenges of Managing and Mining Big Biomedical Data
Data Management Framework
Data Management Platforms
Data Mining in Translational Medicine
Data Mining Techniques and Methods
Big Data and Data Mining
Applications of Data Mining in Translational Medicine
Conclusion
List of Acronyms and Abbreviations
Chapter 3. Modeling and Simulation Applications in Drug Development Process
Introduction
The Role of Modeling and Simulation in Translational Research in Drug Development
Next Level of Contribution from Modeling and Simulation
Chapter 4. Advancements in Omics Sciences
Outline of the Chapter
Introduction
Genomics
Epigenomics
Transcriptomics
Proteomics
Metabolomics
Bioinformatics
Conclusions
Glossary
List of Acronyms and Abbreviations
Chapter 5. Regulatory Process in the United States of America, Europe, China, and Japan
Section 1: Regulatory Process in the United States of America
Section 2: Regulatory Process in Europe, China, and Japan
Chapter 6. Translational Medicine Case Studies and Reports
Introduction
Conclusions
Glossary
List of Acronyms and Abbreviations
Chapter 7. Translational Approaches in Alzheimer’s Disease
Alzheimer Disease and the Role of Amyloid
Therapeutic Approaches
Clinical Trials and Biomarkers
Concluding Comments and Future Directions
Glossary
List of Acronyms and Abbreviations
Index
No. of pages: 196
Language: English
Edition: 1
Published: November 24, 2015
Imprint: Academic Press
Paperback ISBN: 9780128034606
eBook ISBN: 9780128034941
AS
Aamir Shahzad
President: European Society for Translational Medicine (EUSTM), Vienna, Austria
School of Medicine, University of Colorado, Aurora, CO, USA
Affiliations and expertise
President: European Society for Translational Medicine (EUSTM), Vienna, Austria
School of Medicine, University of Colorado, Aurora, CO, USA