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Translational Autoimmunity, Volume 4
Autoimmune Diseases in Different Organs
- 1st Edition - May 1, 2022
- Editor: Nima Rezaei
- Language: English
- Paperback ISBN:9 7 8 - 0 - 1 2 - 8 2 4 4 6 6 - 1
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 8 5 9 7 6 - 9
As the autoimmune diseases could affect different organs, Translational Autoimmunity: Autoimmune Diseases in Different Organs addresses the spectrum of autoimmune diseases. The fo… Read more
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Request a sales quoteAs the autoimmune diseases could affect different organs, Translational Autoimmunity: Autoimmune Diseases in Different Organs addresses the spectrum of autoimmune diseases. The fourth volume of Translational Immunology Series focuses on clinical and laboratory details of autoimmune diseases which are broadly categorized into two types of organ-specific autoimmune diseases and non-organ specific autoimmune diseases (also known as systemic autoimmune diseases). Autoimmune rheumatic diseases such as systemic lupus erythematosus and rheumatoid arthritis, autoimmune rheumatic diseases such as diabetes mellitus and thyroid diseases, autoimmune neurologic diseases such as multiple sclerosis, as well as autoimmune hepatobiliary diseases, autoimmune renal diseases and autoimmune cutaneous diseases as the subject of discussion in Translational Autoimmunity: Autoimmune Diseases in Different Organs.
- Comprises major parts that cover basic immunology, clinical aspects of autoimmunity, and translational immunology studies in autoimmunity
- Each and every key concept will be mentioned after an easy background is drawn and then, will be supported by a systematic appraisal of the most recent evidence
- Can help students at all the academic levels while applicable to scientists who work with autoimmunity
- Designed for learning, teaching, review and testing, practice, and research. Hence, it might be useful for students, teachers and instructors, physicians, and researchers
Clinical immunologists; Endocrinologists; Microbiologists; Neurologists; Oncologists; Rheumatologists. Clinicians, research scientists, and industry partners
- Cover image
- Title page
- Table of Contents
- Copyright
- Dedication
- Contributors
- Preface
- Series editor biography
- Acknowledgment
- Abbreviations
- Chapter 1: Autoimmune diseases in different organs
- Abstract
- 1: Introduction
- 2: Autoimmune complications of the cardiovascular system
- 3: Autoimmune complications of the respiratory system
- 4: Autoimmune complications of the endocrine system
- 5: Autoimmune complications of the gastrointestinal system
- 6: Autoimmune complications of the hematological system
- 7: Autoimmune complications of the musculoskeletal system
- 8: Autoimmune complications of the nervous system
- 9: Autoimmune complications of the integumentary system
- 10: Conclusion
- References
- Chapter 2: Autoimmune polyendocrinopathies in pediatric age
- Abstract
- 1: Introduction
- 2: Autoimmune polyendocrine syndrome type 1 (APS-1)
- 3: Autoimmune polyendocrine syndrome type 2 (APS-2)
- 4: Autoimmune polyendocrine syndrome type 3 (APS-3)
- 5: IPEX syndrome
- 6: Conclusion
- References
- Chapter 3: Autoimmune thyroid diseases: Peculiarities in pediatric age
- Abstract
- 1: Introduction
- 2: Epidemiology
- 3: Pathogenesis
- 4: Thyroid function patterns at presentation
- 5: Clinical manifestations
- 6: Diagnosis
- 7: Thyroid function patterns of evolution over time
- 8: Therapy and management
- 9: Newborn of mother with autoimmune thyroid disease
- 10: Autoimmune thyroid diseases in genetic syndromes
- 11: Conclusion
- References
- Chapter 4: TSH receptor autoantibodies in Graves’ disease
- Abstract
- 1: Introduction
- 2: Basedow-Graves’ disease: Clinical aspects
- 3: Graves’ orbitopathy and myxedema
- 4: Immunopathogenesis of Graves’ disease
- 5: Autoantibodies to the TSH receptor
- 6: Detection and measurement of autoantibodies to TSHR
- 7: Standardization of TRAb measurement
- 8: Use of TRAb in the management of Graves’ disease
- 9: Therapy of Graves’ disease
- 10: Conclusion
- References
- Chapter 5: The heterogeneity of type 1 diabetes: From immunopathology to immune intervention
- Abstract
- 1: Introduction
- 2: Heterogeneity of type 1 diabetes
- 3: The novel concept of T1D endotypes
- 4: Heterogeneity of autoimmune responses and pancreas histopathology in T1D
- 5: The multifaceted pathophysiology of T1D: Beyond insulin, beta cells, and endocrine pancreas
- 6: The heterogeneous response to immunotherapies in T1D
- 7: Conclusion
- References
- Chapter 6: Pathophysiology of autoimmune orbital diseases and target therapy for orbital inflammatory and neoplastic diseases
- Abstract
- 1: Introduction
- 2: Thyroid eye disease
- 3: Idiopathic orbital inflammatory disease (IOIS)
- 4: Oculofacial malignancies
- 5: Conclusion
- References
- Chapter 7: Autoimmune uveitis in childhood
- Abstract
- 1: Introduction
- 2: Juvenile idiopathic arthritis-associated uveitis
- 3: Diagnosis
- 4: Complications
- 5: Treatment
- 6: Conclusion
- References
- Chapter 8: Etiology and pathogenesis of auditory and vestibular dysfunction in patients with autoimmune disorders
- Abstract
- 1: Introduction
- 2: Etiopathogenesis
- 3: Auditory and vestibular symptoms
- 4: Ear symptoms and systemic autoimmune disorders
- 5: Temporal bone aspects (inner and middle ear)
- 6: Conclusion
- References
- Chapter 9: Autoimmune heart disease
- Abstract
- 1: Introduction
- 2: Background
- 3: Organ-specific autoimmunity
- 4: Secondary antibody-mediated autoimmune heart disease
- 5: Conclusion
- References
- Chapter 10: Autoimmunity and its correlation to inflammatory vascular diseases
- Abstract
- 1: Introduction
- 2: Vasculitis
- 3: Conclusion
- References
- Chapter 11: Cryoglobulinemic vasculitis
- Abstract
- 1: Introduction
- 2: Historical background
- 3: Etiology and epidemiology
- 4: Pathogenesis
- 5: Clinical presentations
- 6: Risk of malignancy
- 7: VII: The differential diagnosis
- 8: Diagnosis
- 9: Classification criteria
- 10: Treatment
- 11: Conclusion
- References
- Chapter 12: Immunopathogenesis of acute disseminated encephalomyelitis
- Abstract
- 1: Introduction
- 2: Definition and diagnosis
- 3: Origins and etiologies
- 4: Immunopathogenesis
- 5: Clinical features
- 6: Neurodiagnostic features
- 7: Treatment and prognosis
- 8: ADEM as a herald for relapsing neuroinflammatory disorders
- 9: Conclusion
- References
- Chapter 13: Pulmonary manifestations of autoimmune diseases
- Abstract
- 1: Introduction
- 2: Endocrine
- 3: Systemic inflammatory diseases
- 4: Connective tissue/musculoskeletal/integumentary
- 5: Vascular
- 6: Nervous system
- 7: Gastrointestinal
- 8: Other diseases
- 9: Conclusion
- References
- Chapter 14: Inflammatory bowel diseases: Sex differences and beyond
- Abstract
- 1: Introduction
- 2: Sexual dimorphism in IBDs: Not as “nuanced” as it seems
- 3: Gut microbiome in IBD: Where do we stand?
- 4: Sexual dimorphism in the gut microbiome
- 5: Impact of the gut microbiome on sexual dimorphism in IBDs: Future perspectives and applications, from bench to bedside
- 6: Conclusion
- References
- Chapter 15: Autoimmunity of the liver
- Abstract
- 1: Introduction
- 2: Pathogenesis
- 3: Pathophysiology
- 4: Diagnosis
- 5: Therapy
- 6: Conclusion
- References
- Chapter 16: Advances in autoimmune cutaneous diseases
- Abstract
- 1: Introduction
- 2: Morphea or localized scleroderma
- 3: Dermatomyositis
- 4: Cutaneous lupus erythematosus
- 5: Conclusion
- References
- Chapter 17: Pathogenesis-based treatments in bullous pemphigoid
- Abstract
- 1: Introduction
- 2: Epidemiology
- 3: Pathogenesis
- 4: Clinical manifestations
- 5: Diagnosis
- 6: Differential diagnosis
- 7: Treatment
- 8: Conclusion
- References
- Chapter 18: Autoinflammatory disorders
- Abstract
- 1: Introduction
- 2: Familial Mediterranean fever (FMF)
- 3: Mevalonate kinase deficiency (hyper IgD syndrome)
- 4: Cryopyrin-associated periodic syndrome (CAPS)
- 5: NLRP1-associated autoinflammatory diseases
- 6: TNF receptor-associated periodic syndrome (TRAPS)
- 7: Pyogenic sterile arthritis, pyoderma gangrenosum, and acne (PAPA) syndrome, hyperzincemia, and hypercalprotectinemia
- 8: Chronic recurrent multifocal osteomyelitis and congenital dyserythropoietic anemia (Majeed syndrome)
- 9: Deficiency of the interleukin 1 receptor antagonist (DIRA)
- 10: Cherubism
- 11: Blau syndrome
- 12: CARD14-mediated psoriasis (CAMPS)
- 13: Deficiency of the IL-36 receptor antagonist (DITRA)
- 14: ADAM17 deficiency
- 15: SLC29A3 mutation
- 16: COPA defect
- 17: Otulipenia/ORAS
- 18: AP1S3 deficiency
- 19: A20 deficiency
- 20: ADA2 deficiency
- 21: Aicardi-Goutières syndrome (AGS)
- 22: Spondyloenchondrodysplasia with immune dysregulation (SPENCD)
- 23: STING-associated vasculopathy with onset in infancy (SAVI)
- 24: X-linked reticulate pigmentary disorder
- 25: USP18 deficiency
- 26: Chronic atypical neutrophilic dermatitis with lipodystrophy (CANDLE)
- 27: Singleton-Merten syndrome
- 28: Conclusion
- References
- Index
- No. of pages: 458
- Language: English
- Edition: 1
- Published: May 1, 2022
- Imprint: Academic Press
- Paperback ISBN: 9780128244661
- eBook ISBN: 9780323859769
NR
Nima Rezaei
Professor Nima Rezaei gained his medical degree (MD) from Tehran University of Medical Sciences and subsequently obtained an MSc in Molecular and Genetic Medicine and a PhD in Clinical Immunology and Human Genetics from the University of Sheffield, UK. He also spent a short-term fellowship of Pediatric Clinical Immunology and Bone Marrow Transplantation in the Newcastle General Hospital. Professor Rezaei is now the Full Professor of Immunology and Vice Dean of Research, School of Medicine, Tehran University of Medical Sciences, and the co-founder and Head of the Research Center for Immunodeficiencies. He is also the founding President of the Universal Scientific Education and Research Network (USERN). Professor Rezaei has already been the Director of more than 55 research projects and has designed and participated in several international collaborative projects. Professor Rezaei is an editorial assistant or board member for more than 30 international journals. He has edited more than 35 international books, has presented more than 500 lectures/posters in congresses/meetings, and has published more than 1,000 scientific papers in the international journals.
Affiliations and expertise
Professor, Department of Immunology, School of Medicine; Head, Research Center for Immunodeficiencies, Children’s Medical Center, Tehran University of Medical Sciences; Founding President, Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA),Universal Scientific Education and Research Network (USERN),Tehran, IranRead Translational Autoimmunity, Volume 4 on ScienceDirect