Transgenerational Epigenetics
- 3rd Edition - August 1, 2027
- Latest edition
- Editor: Trygve O. Tollefsbol
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 3 3 2 5 9 - 3
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 3 3 2 6 0 - 9
“Transgenerational Epigenetics, Third Edition”, examines the complex mechanisms, processes, and clinical applications of generational epigenetic inheritance, offering a comprehensi… Read more
Purchase options
“Transgenerational Epigenetics, Third Edition”, examines the complex mechanisms, processes, and clinical applications of generational epigenetic inheritance, offering a comprehensive and updated resource for researchers and clinicians. This edition provides valuable insights into how epigenetic modifications are passed down through generations, impacting health and disease. The book begins with foundational chapters on the definitions, history, and methods of generational epigenetic inheritance, setting the stage for more detailed explorations. It covers the latest advances in genomics, computational epigenetics, and the role of small and long non-coding RNAs in epigenetic inheritance. The text also examines the evolutionary perspectives and model organisms used in this field, providing a broad understanding of the subject. Organized into eight sections, the book addresses key areas such as parental epigenetic inheritance, basic mechanisms and processes, environmental effects on offspring, and the impact on health and disease. Notable new topics include the epigenetic inheritance of cancer, neuroscience aspects, and reproductive diseases, offering cutting-edge information on these critical areas. Additionally, the book discusses the clinical significance of transgenerational epigenetics, highlighting its implications for understanding and treating various diseases. This edition is an essential resource for basic scientists and clinical researchers interested in the latest developments in transgenerational epigenetics. It also serves as a valuable reference for advanced students, university researchers, and professionals in genetics, molecular biology, pharmaceutical science, and biotechnology. By consolidating the most recent research and advancements, this book provides readers with a unique and authoritative source of knowledge in the field.
• Explores new topics including epigenetic inheritance and cancer, neuroscience aspects, and reproductive diseases
• Updates information with the latest advancements in the field, reflecting six years of progress since the last edition
• Revises and enhances chapters authored by leading experts from the first edition
• Analyzes the impact of environmental factors and lifestyle on transgenerational epigenetics
• Updates information with the latest advancements in the field, reflecting six years of progress since the last edition
• Revises and enhances chapters authored by leading experts from the first edition
• Analyzes the impact of environmental factors and lifestyle on transgenerational epigenetics
Basic scientists, clinical researchers, advanced undergraduate students, graduate students, university researchers, pharmaceutical company researchers, biotechnology researchers
1. Epigenetic Inheritance
Section I: Definitions, History and Methods of Generational Epigenetic Inheritance
2. Definition of Epigenetic Transgenerational Inheritance and Biological Impacts
3. Historical Perspective of Transgenerational Epigenetics
4. Advances in Genomics and Their Application to Epigenetic Inheritance
5. Computational Epigenetic Inheritance
Section II: Parental Epigenetic Inheritance
6. Maternal Epigenetic Inheritance
7. Paternal Epigenetic Inheritance
8. Epigenetic Inheritance Across Multiple Generations
Section III: Basic Mechanisms/Processes of Epigenetic Inheritance
9. Towards the Molecular Mechanisms of Transgenerational Epigenetic Inheritance: Insights from Transgenic Mice
10. Histone-mediated Transgenerational Epigenetics
11. Heritable Generational Epigenetic Effects Through Small Non-coding RNA
12. Long Non-coding RNA and Epigenetic Inheritance
Section IV: Evolution of Transgenerational Epigenetics
13. Evolutionary Perspectives on Transgenerational Epigenetics
14. Inheritance of Epigenome Variants Across Generations
Section V: Model Organisms
15. Nonmammalian Model Organisms in Epigenetic Inheritance Research: An Overview
16. Animal Models of Transgenerational Epigenetic Effects
17. Plant Models of Transgenerational Epigenetic Inheritance
18. Epigenetics and Heritable Phenotypic Variations in Livestock
19. Epigenetic Inheritance in Insects
Section VI: Environmental Epigenetic Effects on the Offspring
20. Environmental Transgenerational Epigenetics
21. Impact of Parental Diet on Transgenerational Epigenetics
22. Effect of Parental Physical Activity on the Offspring
23. Transgenerational Epigenetics of Endocrine Disrupting Chemicals in Mammals
24. Transgenerational Effects of Imprinting
Section VII: Impact of Transgenerational Epigenetics on Health and Disease
25. Epidemiology of Transgenerational Epigenetics
26. Transgenerational Epigenetics, Paternal Obesity, and Insulin Resistance
27. Epigenetic Inheritance of Type 2 Diabetes
28. Epigenetic Transgenerational Inheritance of Reproductive Disease
29. Cardiovascular Disease and Transgenerational Epigenetic Effects
30. Epigenetic Inheritance and Cancer
31. Neuroscience Aspects of Transgenerational Epigenetics
32. Epigenetic Inheritance and Aging
Section VIII: Clinical Significance of Transgenerational Epigenetics
33. Clinical Aspects of Transgenerational Epigenetics
Section I: Definitions, History and Methods of Generational Epigenetic Inheritance
2. Definition of Epigenetic Transgenerational Inheritance and Biological Impacts
3. Historical Perspective of Transgenerational Epigenetics
4. Advances in Genomics and Their Application to Epigenetic Inheritance
5. Computational Epigenetic Inheritance
Section II: Parental Epigenetic Inheritance
6. Maternal Epigenetic Inheritance
7. Paternal Epigenetic Inheritance
8. Epigenetic Inheritance Across Multiple Generations
Section III: Basic Mechanisms/Processes of Epigenetic Inheritance
9. Towards the Molecular Mechanisms of Transgenerational Epigenetic Inheritance: Insights from Transgenic Mice
10. Histone-mediated Transgenerational Epigenetics
11. Heritable Generational Epigenetic Effects Through Small Non-coding RNA
12. Long Non-coding RNA and Epigenetic Inheritance
Section IV: Evolution of Transgenerational Epigenetics
13. Evolutionary Perspectives on Transgenerational Epigenetics
14. Inheritance of Epigenome Variants Across Generations
Section V: Model Organisms
15. Nonmammalian Model Organisms in Epigenetic Inheritance Research: An Overview
16. Animal Models of Transgenerational Epigenetic Effects
17. Plant Models of Transgenerational Epigenetic Inheritance
18. Epigenetics and Heritable Phenotypic Variations in Livestock
19. Epigenetic Inheritance in Insects
Section VI: Environmental Epigenetic Effects on the Offspring
20. Environmental Transgenerational Epigenetics
21. Impact of Parental Diet on Transgenerational Epigenetics
22. Effect of Parental Physical Activity on the Offspring
23. Transgenerational Epigenetics of Endocrine Disrupting Chemicals in Mammals
24. Transgenerational Effects of Imprinting
Section VII: Impact of Transgenerational Epigenetics on Health and Disease
25. Epidemiology of Transgenerational Epigenetics
26. Transgenerational Epigenetics, Paternal Obesity, and Insulin Resistance
27. Epigenetic Inheritance of Type 2 Diabetes
28. Epigenetic Transgenerational Inheritance of Reproductive Disease
29. Cardiovascular Disease and Transgenerational Epigenetic Effects
30. Epigenetic Inheritance and Cancer
31. Neuroscience Aspects of Transgenerational Epigenetics
32. Epigenetic Inheritance and Aging
Section VIII: Clinical Significance of Transgenerational Epigenetics
33. Clinical Aspects of Transgenerational Epigenetics
- Edition: 3
- Latest edition
- Published: August 1, 2027
- Language: English
TO
Trygve O. Tollefsbol
Dr. Tollefsbol is a Distinguished Professor of Biology and a Senior Scientist in the O’Neal Comprehensive Cancer Center, Integrative Center for Aging Research, Nutrition Obesity Research Center, University Wide Microbiome Center, and the Comprehensive Diabetes Center at the University of Alabama at Birmingham (UAB). He is Director of the UAB Cell Senescence Culture Facility which he established in 1999. Dr. Tollefsbol trained as a Postdoctoral Fellow and Assistant Research Professor with members of the National Academy of Science at Duke University and the University of North Carolina. He earned doctorates in molecular biology and osteopathic medicine from the University of North Texas Health Sciences Center and his bachelor’s degree in Biology from the University of Houston. He has received prior funding from the NCI, NHLBI, NIMH and other federal institutes as well as the Glenn Foundation for Medical Research, Susan G. Komen for the Cure, the American Federation for Aging Research (AFAR), and the American Institute for Cancer Research (AICR) among many other sources.
Affiliations and expertise
Distinguished Professor of Biology, University of Alabama at Birmingham, AL, USA