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Elsevier

TRAIL

  • 1st Edition, Volume 67 - May 7, 2004
  • Latest edition
  • Editor: Gerald Litwack
  • Language: English

The discovery of TRAIL (TNF Related Apoptosis Inducing Ligand), also referred to as Apo-2, is in an era of intense research because TRAIL induces many cancer cells to undergo… Read more

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Description

The discovery of TRAIL (TNF Related Apoptosis Inducing Ligand), also referred to as Apo-2, is in an era of intense research because TRAIL induces many cancer cells to undergo programmed cell death (apoptosis), while having no effect on normal cells. This important protein deserves extensive review at a formative time in the devlopement of our knowledge concerning its mechanism of action and the ways in which it can be used as a cancer chemotherapeutic agent. Consequently, this voume reviews the current status of research on TRAIL.

Key features

Selected Contents:* Crystal Structure of RANK Ligand involved in bone metabolism* Promoter of TRAIL-R2 Gene* Monoclonal Antibodies against TRAIL* Modulation of TRAIL signaling complex* TRAIL in the airways* FLIP Protein and TRAIL-Induced Apoptosis* TRAIL and Ceramide* TRAIL and Viral Infection* TRAIL and Malignant Glioma

Readership

Molecular biologists, cellular biologists, & biochemists

Product details

  • Edition: 1
  • Latest edition
  • Volume: 67
  • Published: July 6, 2004
  • Language: English

About the editor

GL

Gerald Litwack

Dr. Litwack has authored 3 textbooks on biochemistry and hormones (one with John Wiley & Sons and 2 with Academic Press/Elsevier) and he has edited more than 70 volumes in the Vitamins & Hormones series (Academic Press/Elsevier); he has edited 14 volumes entitled Biochemical Actions of Hormones (Academica Press); He has edited (with David Kritchevsky) Actions of Hormones on Molecular Processes (Academic Press)

Affiliations and expertise
Emeritus Founding Chair and Professor, Geisinger Commonwealth School of Medicine, United States Emeritus Professor, Rutgers University, United States

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