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Toxicological Risk Assessment and Multi-System Health Impacts from Exposure
- 1st Edition - August 1, 2021
- Editor: Aristidis M. Tsatsakis
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 8 5 2 1 5 - 9
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 8 5 3 5 8 - 3
Toxicological Risk Assessment and Multisystem Health Impacts From Exposure highlights the emerging problems of human and environmental health attributable to cumulative and multip… Read more
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Request a sales quote- Bridges basic research with clinical, epidemiological, regulatory, and translational research, conveying both an introductory understanding and the latest developments in the field
- Evaluates real-life human health risk assessment for long-term exposures to xenobiotic mixtures and the role they play in contributing to chronic disease
- Discusses advances in predictive (in silico) toxicology tools and the benefits of using omics technologies in toxicology research
Part 1: Modern tools and concepts in toxicology testing
1. Mixture toxicity evaluation in modern toxicology
2. Alternative methods and their role in modern toxicology
3. The exposome—a new paradigm for nonanimal toxicology and integrated risk assessment
4. In silico toxicology, a robust approach for decision-making in the context of next-generation risk assessment
5. Safety science in the 21st century—a scientific revolution in its making
6. Chemobrain
Part 2: Methods and toxicity models in toxicology
7. "Predictive in silico toxicology." An update on modern approaches and a critical analysis of its strong and weak points
8. Analytical strategies to study the gut microbiome in toxicology
9. Behavioral endpoints in adult and developmental neurotoxicity: the case of organophosphate pesticides
10. Nuclear factor erythroid 2-related factor 2-mediated antioxidant response as an indicator of oxidative stress
11. The potential of complex in vitro models in pharmaceutical toxicology
Part 3: New insights in risk assessment
12. Health-based exposure limits and toxicology in pharmaceutical industry
13. The hormetic dose response: implications for risk assessment
14. Endocrine disruption and human health risk assessment in light of real-life risk simulation
15. Toxicity data as the basis for acute and short-term emergency exposure guidance
16. Renal mitochondria as sentinels for exposures to environmental toxicants and nephrotoxic drugs
Part 4: Clinical biomarkers updates
17. Updates on current biomarkers in toxicology
18. The role of extracellular matrix in allergic contact dermatitis pathogenesis
19. Review of current neurotoxicology issues
20. Modern aspects of immunotoxicology
21. Toxicology of neurodegenerative diseases
22. Toxicogenetics—Pharmacogenetics: genetic variability profiling for xenobiotic response heterogeneity
23. Current and emerging concepts of cardiotoxicity
24. Metabolomics: diagnostic and therapeutic applications in clinical medicine and pharmacology
25. Metabolomics methodology and workflow: challenges and future prospects
26. Telomere length: associations with nutrients and xenobiotics
Part 5: Epidemiology and public health toxicology issues
27. Dismissing the use of P-values and statistical significance testing in scientific research: new methodological perspectives in toxicology and risk assessment
28. Modern approaches for the assessment of human exposure to dietary mycotoxins
29. Tobacco toxicity and regulatory science
30. Dethroning the crown. From the kinetics and dynamics of COVID-19 diagnosis to the promising treatments
31. Toxicology issues related to COVID-19 outbreak
32. Risk assessment for heat stress during work and leisure
Part 6: Pharmaceuticals and nutraceuticals toxicology updates
33. Polyphenols: the hallmark of endothelial dysfunction combatants
34. Effect of diet, pharmaceuticals, and environmental toxicants on gut microbiota imbalance and increased intestinal membrane permeability
35. Hydrogen sulfide: a shifting paradigm
36. Redox biomarkers in toxicology and nutrition: the social link
37. Safety profile of plants and phytoconstituents used in traditional medicine worldwide
Part 7: Toxicology of biomaterials and nanomaterials
38. Epigenetic mechanisms in nanomaterial toxicity
39. Predictive nanotoxicology: from nanotoxicity to nanosafety of select and commonly used nanomaterials
40. The toxicological effects of titanium dioxide nanoparticles on marine microalgae
41. Aquatic nanotoxicology: reference species and omics technologies
Part 8: Special topics in toxicology
42. Toxicity of arsenicals in diseases: friend or foe?
43. Toxicity of psychedelic drugs
44. Immunotoxicity of pesticides: current knowledge and perspectives
45. Glyphosate-based herbicides: evidence of immune-endocrine alteration
46. Ciguatera toxins: toxicity and food safety
47. Cannabinoids and psychosis: current challenges of mechanistic toxicology
48. Electronic cigarettes as a harm reduction concept for public health
- No. of pages: 684
- Language: English
- Edition: 1
- Published: August 1, 2021
- Imprint: Academic Press
- Paperback ISBN: 9780323852159
- eBook ISBN: 9780323853583
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