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Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics

  • 8th Edition - June 22, 2018
  • Latest edition
  • Author: Nader Rifai
  • Language: English

Get the foundational knowledge you need to successfully work in a real-world, clinical lab with Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, 8th Editi… Read more

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Description

Get the foundational knowledge you need to successfully work in a real-world, clinical lab with Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, 8th Edition. From highly respected clinical chemistry expert Nader Rifai, this condensed, easier-to-understand version of the acclaimed Tietz Textbook of Clinical Chemistry and Molecular Diagnostics uses a laboratory perspective to guide you through selecting and performing diagnostic lab tests and accurately evaluating the results. Coverage includes laboratory principles, analytical techniques, instrumentation, analytes, pathophysiology, and more. This eighth edition features new clinical cases from The Coakley Collection, new questions from The Deacon’s Challenge of Biochemical Calculations Collection, plus new content throughout the text to ensure you stay ahead of all the latest techniques, instrumentation, and technologies.

Key features

  • Condensed version of the clinical chemistry "bible" offers the same authoritative and well-presented content in a much more focused and streamlined manner
  • Coverage of analytical techniques and instrumentation includes optical techniques, electrochemistry, electrophoresis, chromatography, mass spectrometry, enzymology, immunochemical techniques, microchips, automation, and point of care testing
  • Updated chapters on molecular diagnostics cover the principles of molecular biology, nucleic acid techniques and applications, and genomes and nucleic acid alterations, reflecting the changes in this rapidly evolving field
  • Learning objectives, key words, and review questions are included in each chapter to support learning
  • More than 500 illustrations plus easy-to-read tables help readers better understand and remember key concepts

Table of contents

PART I: PRINCIPLES OF LABORATORY MEDICINE

1. Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine

2. Analytical and Clinical Evaluation of Methods

3. Preanalytical Variation

4. Biological Variation

5. Establishment and Use of Reference Values

6. Specimen Collection, Processing, and Other Preanalytical Variables

7. Quality Management

8. Principles of Basic Techniques and Laboratory Safety

PART II: ANALYTICAL TECHNIQUES AND INSTRUMENTATION

9. Optical Techniques

10. Electrochemistry and Chemical Sensors

11. Electrophoresis

12. Chromatography

13. Mass Spectrometry

14. Enzyme and Rate Analyses

15. Immunochemical Techniques

16. Automation

17. Point-of-Care Testing

PART III: ANALYTES

18. Amino Acids, Peptides, and Proteins

19. Serum Enzymes

20. Tumor Markers

21. Kidney Function Tests - Creatinine, GFR, Urea, and Uric Acid

22. Carbohydrates

23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Factors

24. Electrolytes and Blood Gases

25. Hormones

26. Catecholamines and Serotonin

27. Vitaminsand Trace Elements,

28. Hemoglobin, Iron, and Bilirubin

29. Porphyrins and Porphyrias

30. Therapeutic Drug Monitoring

31. Clinical Toxicology

32. ToxicElements

PART IV: PATHOPHYSIOLOGY

33. Diabetes Mellitus

34. Cardiovascular Disease

35. Kidney Disease

36. Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism

37. Liver Disease

38. Gastrointestinal and Pancreatic Diseases

39. Disorders of Bone and Mineral Metabolism

40. Disorders of the Pituitary Gland

41. Disorders of the Adrenal Cortex

42. Thyroid Disorders

43. Reproduction-Related Disorders

44. Pregnancy and Prenatal Testing

45. Newborn Screening and Inborn Errors of Metabolism

46. Pharmacogenetics

PART V: MOLECULAR DIAGNOSTICS

47. Molecular Principles

48. Molecular Techniques

49. Molecular Applications

Appendix Reference Information for the Clinical Laboratory

Product details

  • Edition: 8
  • Latest edition
  • Published: December 3, 2018
  • Language: English

About the author

NR

Nader Rifai

Affiliations and expertise
Professor, Department of Pathology Harvard Medical School; The Louis Joseph Gay-Lussac Chair in Laboratory Medicine Boston Children's Hospital; Director of Clinical Chemistry Laboratory Medicine Boston Children's Hospital Boston, Massachusetts, USA