Thyroid Hormones
- 1st Edition - January 1, 1978
- Imprint: Academic Press
- Editor: Choh Hao Li
- Language: English
- Paperback ISBN:9 7 8 - 0 - 1 2 - 4 0 5 3 7 9 - 3
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 1 6 2 9 8 - 2
Hormonal Proteins and Peptides, Volume VI: Thyroid Hormones is a compilation of papers that details the various aspects, chemical properties, effects, and history of thyroid… Read more
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Request a sales quoteHormonal Proteins and Peptides, Volume VI: Thyroid Hormones is a compilation of papers that details the various aspects, chemical properties, effects, and history of thyroid hormones. The book covers a wide range of topics related to the study of thyroid hormones. Six chapters are devoted to the various aspects of thyroid hormones. Chapter 1 deals with the chemistry of human thyrotropin. Chapters 2 and 3 survey the chemistry of thyroid hormones and analogs, focusing on synthesis and structure-activity relationships. Chapter 4 presents thyroxin action and the possible direct participation of thyroxin in catecholamine pathways in the nervous system. Chapter 5 discusses the thyroid hormone action during amphibian metamorphosis at the cellular and molecular levels. An account of the evolution of the thyroid function is given in Chapter 6. The final chapter delves on the historical aspect of thyroid hormones. Biochemists, physicians, pharmacologists, researchers, and students in the medical field will benefit from this book.
List of Contributors
Preface
Contents of Previous Volumes
1. Chemistry of Human Pituitary Thyrotropin
I. Introduction
II. Isolation Procedures
III. Chemical and Physical Characteristics
IV. Chemical Composition
V. Preparation and Properties of the Subunits
VI. Biological Properties of Thyrotropin
VII. Primary Structure of the Subunits
VIII. Chemical Similarities among Human Glycoprotein Hormones
IX. Immunological Characteristics of Thyrotropin
X. Relationship between Pituitary Thyrotropin and Human Chorionic Thyrotropin
XI. Concluding Remarks
References
2. Thyroid Hormones and Analogs. I. Synthesis, Physical Properties and Theoretical Calculations
I. Introduction
II. Methods of Synthesis
III. Physical Properties
IV. Theoretical Calculations
References
3. Thyroid Hormones and Analogs. II. Structure-Activity Relationships
I. Introduction
II. Biological Test Systems
III. Structure-Activity Relationships
IV. General Summary and Comments
References
4. The Mechanism of Thyroxine Action
I. Overview
II. Role of Iodocompounds
III. General Aspects of Iodothyronine Action
IV. Requirements of a Comprehensive Hypothesis of Thyroid Hormone Action
V. Mechanisms of Thyroid Hormone Action: Current Hypotheses
VI. Concluding Statement
References
5. Cellular and Molecular Aspects of Thyroid Hormone Action during Amphibian Metamorphosis
I. Introduction
II. Thyroid Hormones
III. Amphibian Metamorphosis
IV. Metabolic Regulation and Calorigenesis
V. Primary Events and Mechanism of Thyroxine Action
VI. Summary
VII. Addendum
References
6. Evolution of Thyroid Function
I. Introduction
II. Iodoproteins in Invertebrates
III. Prevertebrates and Primitive Vertebrates
IV. Thyroid Gland Secretions
References
7. The Thyroid Hormones: Historical Aspects
I. Introduction
II. The Colloid of the Thyroid
III. Thyroxine: E.C. Kendall
IV. Thyroxine: C.R. Harington
V. Configurative Relationship between Throxine and Tyrosine
VI. Glaxo Synthesis of L-Thyroxine
VII. Isolation of Diiodotyrosine from the Thyroid Gland
VIII. The Circulating Thyroid Hormone
IX. Thyroxine and Total Thyroidal Activity
X. Radioactive Iodine in Thyroid Research
XI. Triiodothyronine
XII. Other Iodothyronines
References
Author Index
Subject Index
- Edition: 1
- Published: January 1, 1978
- No. of pages (eBook): 462
- Imprint: Academic Press
- Language: English
- Paperback ISBN: 9780124053793
- eBook ISBN: 9780323162982