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Elsevier

Thompson & Thompson Genetics in Medicine

  • 8th Edition - May 5, 2015
  • Latest edition
  • Authors: Robert L. Nussbaum, Roderick R. McInnes, Huntington F Willard
  • Language: English

Updated to reflect the newest changes in genetics, Thompson & Thompson's Genetics in Medicine returns as one of the most favored texts in this fascinating and rapidly evolving… Read more

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Description

Updated to reflect the newest changes in genetics, Thompson & Thompson's Genetics in Medicine returns as one of the most favored texts in this fascinating and rapidly evolving field. By integrating the classic principles of human genetics with modern molecular genetics, this medical reference book utilizes a variety of learning tools to help you understand a wide range of genetic disorders.

Key features

  • Acquire the state-of-the-art knowledge you need on the latest advances in molecular diagnostics, the Human Genome Project, pharmacogenetics, and bio-informatics
  • Better understand the relationship between basic genetics and clinical medicine with a variety of clinical case studies
  • Recognize a wide range of genetic disorders with visual guidance from more than 240 dynamic illustrations and high-quality photos

Table of contents

1. Introduction

2. Introduction to the Human Genome

3. The Human Genome: Gene Structure and Function

4. Human Genetic Diversity: Mutation and Polymorphism

5. Principles of Clinical Cytogenetics and Genome Analysis

6. The Chromosomal and Genomic Basis of Disease: Disorders of the Autosomes and Sex Chromosomes

7. Patterns of Single-Gene Inheritance

8. Complex Inheritance of Common Multifactorial Disorders

9. Genetic Variation in Populations

10. Identifying the Genetic Basis for Human Disease

11. The Molecular Basis of Genetic Disease

12. The Molecular, Biochemical, and Cellular Basis of Genetic Disease

13. The Treatment of Genetic Disease

14. Developmental Genetics and Birth Defects

15. Cancer Genetics and Genomics

16. Risk Assessment and Genetic Counseling

17. Prenatal Diagnosis and Screening

18. Application of Genomics to Medicine and Personalized Health Care

19. Ethical and Social Issues in Genetics and Genomics

Review quotes

"This eighth edition is masterfully written by Nussbaum, McInnes, and Willard. Widely known as Thompson and Thompson, this is an instrumental book in the field." --Luis F. Escobar, MD, MS (St. Vincent Hospital and Health Care Center) Doody’s Score: 100 - 5 Stars!

Product details

  • Edition: 8
  • Latest edition
  • Published: May 27, 2015
  • Language: English

About the authors

RN

Robert L. Nussbaum

Affiliations and expertise
Holly Smith Chair of Medicine and Science, Professor of Medicine, Neurology, Pediatrics and Pathology, Department of Medicine and Institute for Human Genetics, University of California San Francisco, San Francisco, California

RM

Roderick R. McInnes

Affiliations and expertise
Alva Chair in Human Genetics, Canada Research Chair in Neurogenetics, Professor of Human Genetics and Biochemistry, Director, Lady Davis Institute, Jewish General Hospital, McGill University, Montreal, Quebec, Canada

HW

Huntington F Willard

Huntington Willard is on the faculty of the Department of Human Genetics at the University of Chicago. Prior to this appointment, Willard was the President and Director of the Marine Biological Laboratory and Professor of Human Genetics at the University of Chicago. He was previously on the faculty at Duke University, where he was founding director of the university-wide Duke Institute for Genome Sciences & Policy from 2003 to 2014, the Nanaline H. Duke Professor of Genome Sciences, and the Arts & Sciences Professor of Biology & Genome Sciences.
Affiliations and expertise
Chief Scientific Officer, Genome Medical, Inc., South San Francisco, CA, USA