The Zebrafish: Genetics and Genomics
Genetics and Genomics
- 1st Edition, Volume 60 - December 21, 1998
- Latest edition
- Editors: H. William Detrich III, Leslie Wilson, Leonard I. Zon, Paul T. Matsudaira, Monte Westerfield
- Language: English
This is the second volume of a two-volume, comprehensive treatment of the methodologies used in researching the Zebrafish, an emerging vertebrate model system. The text includes… Read more
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This is the second volume of a two-volume, comprehensive treatment of the methodologies used in researching the Zebrafish, an emerging vertebrate model system. The text includes discussions on development, genetic methodologies, and model applications.
@introbul:Key Features@bul:* Details state-of-the-art zebrafish protocols in a single-source reference* Presents methods and reagents in user-friendly format* Delineates critical steps and pitfalls of he procedures* Illustrates techniques with full-color plates* Summarizes many new and interesting developmental mutants* Includes appendices with strain information and a compendium of zebrafish World Wide Web sites* Is relevant to clinicians interested in vertebrate models of human congenital diseases
AUDIENCE: Students and researchers who employ molecular, cellular, and genetic/genomic methods to study vertebrate development.
Contributors.Preface.A Gynogenesis-Based Screen for Maternal-Effect Genes in the Zebrafish, D. Rerio.Developmental Mutant Screens in the Zebrafish, F.J.M. van Eeden, M. Granato, J. Odenthal, and P. Haffter.Haploid Screens and Gamma-Ray Mutagenesis, C. Walker.Early Pressure Screens, C.E. Beattie, D.W. Raible, P.D. Henion, and J.S. Eisen.Retrovirus-Mediated Insertional Mutagenesis in Zebrafish, A. Amsterdam and N. Hopkins.Genetic Applications of Transposons and Other Repetitive Elements in Zebrafish, Z. Ivics, Z. Izsvák and P.B. Hackett.Transgenesis, A. Meng, J.R. Jessen and S. Lin.The Zebrafish Genome, J. Postlethwait, A. Amores, A. Force and Y.-L. Yan.Using Random Amplified Polymorphic DNAs in Zebrafish Genomic Analysis, J.H. Postlethwait, Y.-L. Yan and M.A. Gates.Simple Sequence-Length Polymorphism Analysis, E.C. Liao and L.I. Zon.Gene Mapping in Zebrafish Using Single-Strand Conformation Polymorphism Analysis, D. Foernzler and D. R. Beier.Mapping Zebrafish Mutations by AFLP, D.G. Ransom and L.I. Zon.Zebrafish Expressed Sequence Tags and Their Applications, Z. Gong.Zebrafish YAC, BAC, and PAC Genomic Libraries, C.T. Amemiya, T.P. Zhong, G.A. Silverman, M.C. Fishman and L.I. Zon.Positional Cloning of Mutated Zebrafish Genes, W.S. Talbot and A.F. Schier.Construction and Characterization of Zebrafish Whole Genome Radiation Hybrids, C. Kwok, R. Critcher and K. Schmitt.Zebrafish/Mouse Somatic Cell Hybrids for the Characterization of the Zebrafish Genome, M. Ekker, F. Ye, L. Joly, P. Tellis and M. Chevrett.Banded Chromosomes and the Zebrafish Karyotype, A. Amores and J.H. Postlethwait.Zebrafish Informatics and the ZFIN Database, M. Westerfield, E. Doerry, A.E. Kirkpatrick and S.A. Douglas.Appendix 1: Genetic Backgrounds and Some Standard Stocks and Strains Used in Zebrafish Developmental Biology and Genetics, S.L. Johnson and L.I. Zon.Appendix 2: Centromeric Markers in the Zebrafish, D. Kane, L.I. Zon and H.W. Detrich, III.Appendix 3: Collection, Storage, and Use of Zebrafish Sperm, D.G. Ransom and L.I. Zon.Appendix 4: Zebrafish Web Site Listings, P. Edwards.Index.
- Edition: 1
- Latest edition
- Volume: 60
- Published: December 21, 1998
- Language: English
HD
H. William Detrich III
Professor of Biochemistry and Marine Biology at Northeastern University, promoted 1996. Joined Northeastern faculty in 1987. Previously a faculty member in Dept. of Biochemistry at the University of Mississippi Medical Center, 1983-1987.Principal Investigator in the U.S. Antarctic Program since 1984. Twelve field seasons "on the ice" since 1981. Research conducted at Palmer Station, Antarctica, and McMurdo Station, Antarctica.Research areas: Biochemical, cellular, and physiological adaptation to low and high temperatures. Structure and function of cytoplasmic microtubules and microtubule-dependent motors from cold-adapted Antarctic fishes. Regulation of tubulin and globin gene expression in zebrafish and Antarctic fishes. Role of microtubules in morphogenesis of the zebrafish embryo. Developmental hemapoiesis in zebrafish and Antarctic fishes. UV-induced DNA damage and repair in Antarctic marine organisms.
Affiliations and expertise
Professor of Biochemistry and Marine Biology at Northeastern UniversityLW
Leslie Wilson
University of California, Santa Barbara, USA
Affiliations and expertise
University of California, Santa Barbara, USALZ
Leonard I. Zon
Affiliations and expertise
Howard Hughes Medical Institute, Children's Hospital, Boston, MA, USAPM
Paul T. Matsudaira
Affiliations and expertise
Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, U.S.A.MW
Monte Westerfield
Professor, Department of Biology, Institute of Neuroscience, University of Oregon, Eugene, OR, USA
Affiliations and expertise
Professor, Department of Biology, Institute of Neuroscience, University of Oregon, Eugene, OR, USA