The Spleen and Some of Its Diseases

I.-Anatomy of the Spleen Relations Peritoneal Attachments Blood-Supply Surface Markings Significance of Anatomical Features Occasional AbsenceII.-The Surgery of the Spleen History Association of Spleen with Laughter, and with Speed in Running Early Records of Splenectomy Experimental Observations Cases of Absent Spleen Splenectomy in Modern TimesIII.-On the Functions of the Spleen Brief Consideration of the Minute Anatomy and Physiology of the Spleen and Liver Lines of Inquiry and Research Results of Splenectomy in Animals Questions Suggested Thereby Connections of the Spleen with Other Organs The Spleen as a Member of the Hemopoietic System Reticulo-endothelial System Digestive System Sympathico-endocrine SystemIV.-The Pathology of Splenic Diseases Pathological Changes Grouped according to Affinities between Causal Agents and Parts of Spleen-Liver System Affected—Varieties of Toxins Entering or Leaving Spleen, and Their ActionsV.-The Clinical and Associated Phenomena in Splenic Disease Anemia Jaundice Petechial Hemorrhages Muscular Weakness Pyrexia Splenomegaly Leucocytosis Spleen and Hncmorrhagic Diathesis Urobilin in the UrineVI.-Pernicious Anemia (Addison's Anemia, Idiopathic Anemia) History 'Primary' and 'Secondary' Misleading as Applied to Anemia The Blood in Anemia Pathology of Pernicious Anemia Source of Toxin Important Signs and Symptoms Treatment by SplenectomyVII.-Leukemia History Development of Science of Hematology Pathology Symptoms Acute Leukemia Chronic Leukemia TreatmentVIII.-Hodgkin's Disease History Pathology Disorders of the Reticulo-endothelial System Symptoms TreatmentIX.-Splenic Anemia (Banti's Disease) History Clinical Features Differential Diagnosis Pathogenesis TreatmentX.-Hemolytic Jaundice History Congenital and Acquired Types Symptoms Pathogenesis TreatmentXI.-Gaucher's Disease, Von Jaksch's Disease, PolycyXII.-Differential DiagnosisXIII.-On the Liver in Some of Its Relations to the Spleen Multiple Pathological Classifications of Cirrhosis a Source of Confusion Further Consideration of Minute Anatomy and Physiology of Liver Method of Production of Cirrhosis Circulatory and Infective Causes Relationship of Spleen Conception of Liver Acinus as Divided into Solid and Tubular Portions with Different Functions Portal and Biliary Cirrhosis as Variants of a Single Type Surgical Treatment and Its AimsXIV.-Conclusion Splenic Diseases not Isolated Entities but Local Manifestations of Systemic Disorder Search to be Made for Site of Lesion and Type of Infective Agent at Work