The Plasma Proteins V4
Structure, Function, and Genetic Control
- 2nd Edition - November 12, 2012
- Imprint: Academic Press
- Editor: Frank Putnam
- Language: English
- Paperback ISBN:9 7 8 - 0 - 1 2 - 3 9 4 1 8 1 - 7
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 1 6 1 7 3 - 2
The Plasma Proteins: Structure, Function, and Genetic Control is a systematic account of the structure, function, and genetic control of plasma proteins. Advances in the… Read more
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The Plasma Proteins: Structure, Function, and Genetic Control is a systematic account of the structure, function, and genetic control of plasma proteins. Advances in the characterization and posttranslational modification of plasma proteins are discussed, along with the structure of a variety of plasma proteins such as serum albumin, glycoproteins, and serum lipoproteins, and immunoglobulins. Comprised of six chapters, this volume begins with a review of progress in plasma proteins, focusing on their three-dimensional structure, characterization, and microheterogeneity as well as genetic polymorphism and chromosomal mapping. The second chapter gives a comprehensive summary of the structure of nearly 100 proteins, from serum albumin and glycoproteins to serum lipoproteins, thyroxine-binding proteins, and immunoglobulins. The reader is then introduced to human plasma proteins of unknown function, together with high-resolution two-dimensional electrophoretic mapping. The remaining chapters explore developments in the structural study of carbon hydrates; synthesis, structure, and function of the oligosaccharides of plasma glycoproteins; and the evolution of the vertebrate plasma proteins. This monograph will be of interest to molecular biologists and biochemists.
Contributors
Preface
Contents of Other Volumes
1 Progress in Plasma Proteins
I. Introduction
II. Characterization of the Plasma Proteins
III. Microheterogeneity and Posttranslational Modification of Plasma Proteins
IV. Panoramic View of the Plasma Proteins
V. Primary Structure of the Plasma Proteins
VI. Three-Dimensional Structure and Ultrastructure of Plasma Proteins
VII. Hereditary Deficiencies and Genetic Polymorphism of Human Plasma Proteins
VIII. Chromosomal Mapping and Genomic Organization of Human Plasma Proteins
IX. Conclusion
References
2 Alpha, Beta, Gamma, Omega—The Structure of the Plasma Proteins
I. Introduction
II. Serum Albumin and α-Fetoprotein
III. Thyroxine-Binding Proteins
IV. α-Glycoproteins
V. β-Glycoproteins
VI. C-Reactive Protein and Serum Amyloid Proteins
VII. Minor Low-Molecular-Weight Proteins with y or Basic Mobility and Unknown Function
VIII. Serum Lipoproteins
IX. The Complement System
X. Blood Coagulation Proteins
XI. Immunoglobulins
References
3 Human Plasma Proteins of Unknown Function
I. Introduction
II. Description of Human Plasma Proteins of Unknown Function
III. Low-Molecular-Weight Trace Proteins with Basic or y Mobility and Unknown Function
IV. Description of Passenger Proteins with Unknown Function
References
4 High-Resolution Two-Dimensional Electrophoretic Mapping of Plasma Proteins
I. Introduction
II. Two-Dimensional Map of Plasma Proteins
III. Microheterogeneity
IV. Genetic Polymorphism
V. Immunoglobulins
VI. The Future of Protein Mapping
References
5 The Oligosaccharides of Plasma Glycoproteins: Synthesis, Structure, and Function
I. Introduction
II. General Features
III. Regulation of Glycosylation
IV. Function
V. Immunoglobulins
VI. Future Directions
References
6 Evolution of the Vertebrate Plasma Proteins
I. Introduction
II. Four Major Plasma Proteins
III. Two Other Plasma Proteins
IV. Lipoproteins
V. Protease Inhibitors
VI. Complement Proteins
VII. Vertebrate Blood Coagulation
VIII. Overview
References
Appendix: Amino Acid Sequences of Plasma Proteins
I. Introductory Remarks
II. Amino Acid Sequences
Index
- Edition: 2
- Published: November 12, 2012
- Imprint: Academic Press
- Language: English
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