The Neuroscience of Deep Brain Stimulation
Research and Clinical Applications
- 1st Edition - March 1, 2026
- Editors: Yasin Temel, Abdelhamid Benazzouz, Ali Jahanshahi
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 9 9 7 4 2 - 3
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 9 7 4 3 - 0
Neuroscience of Deep Brain Stimulation: Research and Clinical Applications begins by introducing readers to the foundational research and historical background of DBS, includ… Read more
Neuroscience of Deep Brain Stimulation: Research and Clinical Applications begins by introducing readers to the foundational research and historical background of DBS, including developmental experimental models for movement and psychiatric disorders. The second section reviews various clinical applications, including numerous and in-depth case studies. The final section identifies the mechanisms of action behind DBS, including cellular, metabolic, and neurochemical mechanisms. Internationally contributed, this book is an essential guide for anyone in the field of DBS.
- Reviews the development of experimental models for movements and psychiatric disorders
- Identifies brain pathologies that Deep Brain Stimulation has revolutionized
- Summarizes major technological developments for Deep Brain Stimulation and how they have adapted to patients’ needs, including Epilepsy, Tourette’s Syndrome, and Depression
Neuroscientists, Neurologists, Neurophysiologists, Neurosurgeons, Psychiatrists, Psychologists, Physiotherapists, Engineers Industry (Medtronic, Abbott, Boston Scientific) DBS device companies! more than 20 SME’s
Part 1: Bench
1. The quest for a target and the beginning of the DBS-story
2. Early clinical application
3. Development of experimental models for movements disorders
4. Development of experimental models for psychiatric disorders
Part 2: Science behind the clinical application
5. Parkinson’s disease
6. Dystonia
7. Essential tremor
8. Epilepsy
9. OCD
10. Tourette Syndrome
11. Depression
12. Alzheimer’s disease
13. Other indications
Part 3: Mechanisms of action
14. Neurophysiological mechanisms
15. Cellular mechanisms
16. Metabolic mechanisms
17. Neurochemical mechanisms
18. Mechanisms investigated by imaging
Part 4. Future/perspectives
1. The quest for a target and the beginning of the DBS-story
2. Early clinical application
3. Development of experimental models for movements disorders
4. Development of experimental models for psychiatric disorders
Part 2: Science behind the clinical application
5. Parkinson’s disease
6. Dystonia
7. Essential tremor
8. Epilepsy
9. OCD
10. Tourette Syndrome
11. Depression
12. Alzheimer’s disease
13. Other indications
Part 3: Mechanisms of action
14. Neurophysiological mechanisms
15. Cellular mechanisms
16. Metabolic mechanisms
17. Neurochemical mechanisms
18. Mechanisms investigated by imaging
Part 4. Future/perspectives
- Edition: 1
- Published: March 1, 2026
- Language: English
YT
Yasin Temel
Yasin Temel is a Professor of Neurosurgery, Medical Center in Maastricht University, Maastricht, The Netherlands.
Affiliations and expertise
Professor of Neurosurgery, Medical Center, Maastricht University, Maastricht, The NetherlandsAB
Abdelhamid Benazzouz
Research Director Abdelhamid Benazzouz works in the Neurodegenerative Dis Institute, Bordeaux University, France.
Affiliations and expertise
Research Director, Neurodegenerative Dis Institute, Bordeaux University, FranceAJ
Ali Jahanshahi
Experienced academic researcher with a demonstrated history of working in the field of Neuromodulation and Neurodegenerative disorders. Head of functional neurosurgery section at the department of neurosurgery. Skilled in Fundamental Neuromodulation research and academic teaching, Neuroanatomy, Animal Models, Electrophysiology, Behavior, Stereology and Microscopy. Co-founder and coordinator of Neuromodulation Master Specialization at Maastricht University.
Affiliations and expertise
Associate Professor at the Department of Neurosurgery, Maastricht University Medical Center, Maastricht, the Netherlands (0.8fte; permanent) Associate Professor at the Netherlands Institute for Neuroscience (NIN) (0.2fte; permanent)