The Liver and Renal Disease, An Issue of Clinics in Liver Disease

1st Edition, Volume 26-2 - May 2, 2022
Editor: David Bernstein
Language: English
Hardback ISBN:
9 7 8 - 0 - 3 2 3 - 8 9 7 5 8 - 7
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 8 9 7 5 9 - 4

In this issue of Clinics in Liver Disease, guest editor Dr. David Bernstein brings his considerable expertise to the topic of The Liver and Renal Disease. The presence of liver di… Read more

The Liver and Renal Disease, An Issue of Clinics in Liver Disease

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In this issue of Clinics in Liver Disease, guest editor Dr. David Bernstein brings his considerable expertise to the topic of The Liver and Renal Disease. The presence of liver disease in patients with chronic renal disease makes the management of both conditions more challenging. In this issue, top experts in the field address many aspects of the treatment and management of these co-existing conditions.

Cover image
Title page
Table of Contents
Copyright
Contributors
Forthcoming Issues
Preface
Hyponatremia in Cirrhosis
Key points
Introduction
Pathogenesis
Etiology
Diagnostic approach
Therapy
Perioperative management in patients awaiting liver transplant
Summary
Clinics care points
Disclosure
Hepatorenal Syndrome: Pathophysiology
Key points
Introduction
Circulatory dysfunction: “peripheral arterial vasodilation hypothesis”
Circulatory dysfunction: cirrhotic cardiomyopathy
Systemic inflammation
Relative adrenal insufficiency
Other mechanisms of renal dysfunction in cirrhosis
Summary
Hepatorenal Syndrome: Definitions, Diagnosis, and Management
Introduction
Definitions and diagnosis
Hepatorenal syndrome prevention
Hepatorenal syndrome management: efficacy and adverse effects
Assessing response to therapy
Management of patients without response to medical therapy
Summary
Clinics care points
Conflict of interest statement
Author involvement
Glomerular Disease in Liver Disease
Key points
Glomerular disease in liver disease
Summary
Clinics care points
The Interplay Between Nonalcoholic Fatty Liver Disease and Kidney Disease
Key points
Introduction
Summary
Clinics care points
Disclosure
Polycystic Kidney/Liver Disease
Key points
Introduction
Epidemiology
Genetics
Pathophysiology
Natural history
Diagnosis
Management
Summary
Clinics care points
Disclosure
Kidney Replacement Therapy in Patients with Acute Liver Failure and End-Stage Cirrhosis Awaiting Liver Transplantation
Key points
Introduction
Indications for kidney replacement therapy in patients with liver failure
Choosing modality of kidney replacement therapy in liver failure
Continuous kidney replacement therapy
Hemodialysis
Peritoneal dialysis
Intraoperative dialysis during liver transplantation
Albumin dialysis
Summary
Clinics care points
Disclosure
Peritransplant Renal Dysfunction in Liver Transplant Candidates
Key points
Introduction
Pathophysiology
Development and management of acute renal dysfunction in the liver transplant candidate
Novel modalities for the assessment of underlying renal function among cirrhotics
Evaluating cirrhotic patients with renal dysfunction for SLKT
Intraoperative care in patients with renal dysfunction
Renal dysfunction and considerations in the perioperative period
Summary
Clinics care points
Author contributions
Disclosure
Pros and Cons of the Safety Net Rule for Prioritization of Liver Transplant Recipients Who Receive Liver Alone Transplant but Develop End-Stage Renal Disease
Key points
Introduction
Safety net rule
Pros
Cons
Disclosure
Clinics care points
Kidney Allocation Issues in Liver Transplantation Candidates with Chronic Kidney Disease and Severe Kidney Liver Injury
Key points
Model for end-stage liver disease and kidney disease
Background
The problem
The Final Rule and kidney transplant for end-stage renal disease
Clinics care points
Disclosure
The Use of Hepatitis C Virus–Positive Organs in Hepatitis C Virus–Negative Recipients
Key points
Introduction
Evaluation of hepatitis C in the donor
Viral transmission after hepatitis C virus donor-positive recipient-negative liver or kidney transplant
Viral eradication after liver transplant
Viral eradication after hepatitis C virusD+/R− kidney transplant
Duration and timing of treatment in kidney transplant
Duration and timing of treatment in liver transplant
Other outcomes
Choosing the treatment regimen
Cost-effectivity analysis
Summary
Clinics care points
Simultaneous Liver–Kidney Transplantation
Key points
Introduction
Conclusions
Chronic Kidney Disease After Liver Transplantation
Key points
Introduction
Definitions of AKI and CKD
Hepatorenal syndrome
Assessing renal function
Renal dysfunction in LT candidates
Renal dysfunction in LT recipients
CKD after LT
Prevention and management of renal dysfunction in LT recipients
Renal replacement therapy
Simultaneous liver and kidney transplantation
Summary
Clinics care points

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The Liver and Renal Disease, An Issue of Clinics in Liver Disease

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David Bernstein