The Immune Response
Basic and Clinical Principles
- 1st Edition - November 11, 2005
- Authors: Tak W. Mak, Mary E. Saunders
- Language: English
- eBook ISBN:9 7 8 - 0 - 0 8 - 0 5 3 4 4 8 - 0
The Immune Response is a unique reference work covering the basic and clinical principles of immunology in a modern and comprehensive fashion. Written in an engaging conver… Read more
The Immune Response is a unique reference work covering the basic and clinical principles of immunology in a modern and comprehensive fashion. Written in an engaging conversational style, the book conveys the broad scope and fascinating appeal of immunology. The book is beautifully illustrated with superb figures as well as many full color plates. This extraordinary work will be an invaluable resource for lecturers and graduate students in immunology, as well as a vital reference for research scientists and clinicians studying related areas in the life and medical sciences.
- Current and thorough 30 chapter reference reviewed by luminaries in the field
- Unique ‘single voice' ensures consistency of definitions and concepts
- Comprehensive and elegant illustrations bring key concepts to life
- Provides historical context to allow fuller understanding of key issues
- Introductory chapters 1-4 serve as an ‘Immunology Primer' before topics are discussed in more detail
Intended as a reference for senior undergraduate and early graduate students with basic or clinical goals in immunology; teachers and lecturers in immunology; postdoc and research level scientists in immunology and other Life Science areas looking for a refresher/ reference
BASIC IMMUNOLOGY
Perspective on Immunity
Introduction to the Immune Response
Cells and Tissues of the Immune Response
Innate Immunity
B Cell Receptor Structure and Effector Function
Antigen-Antibody Interaction
Exploiting Antigen-Antibody Interaction
The Immunoglobulin Genes
The Humoral Response: B Cell Development and Activation
The Major Histocompatibility Complex
Antigen Processing and Presentation
T Cell Receptor: Structure of its Proteins and Genes
T Cell Development
T Cell Activation
T cell differentiation and effector function
Immune Tolerance in the Periphery
Cytokines and their Receptors
Bridging Innate and Specific Immunity: NK, gd T and NKT cells
Complement
Mucosal and Cutaneous Immunity
Comparative Immunology
CLINICAL IMMUNOLOGY
Immunity to Pathogens
Vaccines and Clinical Immunization
Primary Immunodeficiencies
HIV and Acquired Immunodeficiency Syndrome
Tumor Immunology
Transplantation
Allergy and Hypersensitivity
Autoimmune Disease
Glossary
Appendices
Index
Abbreviations
Perspective on Immunity
Introduction to the Immune Response
Cells and Tissues of the Immune Response
Innate Immunity
B Cell Receptor Structure and Effector Function
Antigen-Antibody Interaction
Exploiting Antigen-Antibody Interaction
The Immunoglobulin Genes
The Humoral Response: B Cell Development and Activation
The Major Histocompatibility Complex
Antigen Processing and Presentation
T Cell Receptor: Structure of its Proteins and Genes
T Cell Development
T Cell Activation
T cell differentiation and effector function
Immune Tolerance in the Periphery
Cytokines and their Receptors
Bridging Innate and Specific Immunity: NK, gd T and NKT cells
Complement
Mucosal and Cutaneous Immunity
Comparative Immunology
CLINICAL IMMUNOLOGY
Immunity to Pathogens
Vaccines and Clinical Immunization
Primary Immunodeficiencies
HIV and Acquired Immunodeficiency Syndrome
Tumor Immunology
Transplantation
Allergy and Hypersensitivity
Autoimmune Disease
Glossary
Appendices
Index
Abbreviations
- Edition: 1
- Published: November 11, 2005
- Language: English
TM
Tak W. Mak
Tak W. Mak is the Director of the Campbell Family Institute for Breast Cancer Research in the Princess Margaret Hospital, Toronto, Canada, and a University Professor in the Departments of Medical Biophysics and Immunology, University of Toronto. He was trained at the University of Wisconsin in Madison, the University of Alberta, and the Ontario Cancer Institute. He gained worldwide prominence in 1984 as the leader of the team that first cloned the genes of the human T cell antigen receptor. His group went on to create a series of genetically altered mice that have proved critical to understanding intracellular programs governing the development and function of the immune system, and to dissecting signal transduction cascades in various cell survival and apoptotic pathways. His current research remains centered on mechanisms of immune recognition/regulation, malignant cell survival/death, inflammation in autoimmunity and cancer, and metabolic adaptation in tumor cells. Dr. Mak has published over 700 papers and holds many patents. He has been granted honorary doctoral degrees from universities in North America and Europe, is an Officer of the Orders of Canada and Ontario, and has been elected a Foreign Associate of the National Academy of Sciences (U.S.), a Fellow of the Royal Society of London (U.K.), and a Fellow of the AACR Academy. Dr. Mak has won international recognition as the recipient of the Emil von Behring Prize, the King Faisal International Prize for Medicine, the Gairdner Foundation International Award, the Sloan Prize of the General Motors Cancer Foundation, the Novartis Prize in Immunology, the Robert Noble Prize, the Killam Prize, the Stacie Prize, the McLaughlin Medal, and the Paul Ehrlich and Ludwig Darmstaedter Prize.
Affiliations and expertise
The Campbell Family Institute for Breast Cancer Research, Ontario, CanadaMS
Mary E. Saunders
Mary E. Saunders holds the position of Scientific Editor for the Campbell Family Institute for Breast Cancer Research, Toronto, Canada. She completed her B.Sc. degree in Genetics at the University of Guelph, Ontario, and received her Ph.D. in Medical Biophysics at the University of Toronto. Dr. Saunders works with Dr. Mak and members of his laboratory on the writing and editing of scientific papers for peer-reviewed journals as well as on various grant applications and book projects. She takes pride and pleasure in producing concise, clear, highly readable text and making complex scientific processes readily understandable.
Affiliations and expertise
The Campbell Family Institute for Breast Cancer Research, Ontario, CanadaRead The Immune Response on ScienceDirect