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The Developing Human
Clinically Oriented Embryology
- 12th Edition - August 1, 2024
- Authors: Mark G. Torchia, T. V. N. Persaud
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 1 1 9 4 8 - 4
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 1 1 6 9 8 - 8
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 1 7 4 0 - 4
Providing an easy-to-digest, comprehensive review of what can be a complex and challenging subject, The Developing Human: Clinically Oriented Embryology, 12th Edition,… Read more
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Request a sales quoteProviding an easy-to-digest, comprehensive review of what can be a complex and challenging subject, The Developing Human: Clinically Oriented Embryology, 12th Edition, covers all aspects of normal and abnormal embryonic and fetal development. In a clear, concise manner, this lavishly illustrated text has been extensively revised to incorporate recent research and current clinical practice guidelines, meeting the needs of medical and health sciences students as well as those in graduate programs. Online features include multiple-choice questions and narrated animations to further support student success.
- Guides you month by month and stage by stage through embryo and fetal organ and systems development, using full-color photographs of clinical cases, relevant modern medical imaging, and numerous high-quality supportive figures.
- Covers timely topics such as signaling pathways used during development, epigenetics, gene editing and CRISPR/Cas9 technology, reproductive in-vitro technology, stem-cell culture and creation and use of human organoids and early embryoids, morphogens, new teratogens (infections and environmental chemicals), and clinical genetics of common birth defects.
- Emphasizes modern clinical imaging techniques, with many new 3D HD color rendered images of embryos and fetuses, 3D constructions of whole embryos, and imaging updates to sections on the head and neck, genitourinary system, ovarian development, nervous system, eyes, and integumentary system.
- Details how molecular biology has affected clinical practice, including techniques such as recumbent DNA technology and stem cell manipulation.
- Contains clinical “Blue Boxes” cases with answers to questions, numerous illustrations, crisp medical imaging figures, and many clinical photographs.
- Provides clinically-oriented problems for each chapter, with corresponding answers and explanations designed to facilitate discussion and learning. In addition, multiple-choice questions and answers are available online for supportive self-assessment.
- Features 18 outstanding, narrated, full-color animations to help you as you explore and learn the complexity of embryological development.
- Provides the knowledge base needed for today's examinations, including USMLE Step 1, as well as for future clinical practice.
- An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.
Medical, dental, graduate students (MSc and PhD), and Residents in the health sciences. Students preparing for the USMLE, Step 1, Science Courses...
- Instructions for Online Access
- Cover image
- Title page
- Table of Contents
- Activate your eBook today!
- Copyright
- Dedication
- Contributors
- Preface
- Acknowledgments
- Get the most out of The Developing Human, 12th Edition!
- Biography
- Tribute to Dr. Keith Leon Moore
- 1. Introduction to Human Development
- Chapter Outline
- DEVELOPMENTAL PERIODS
- SIGNIFICANCE OF EMBRYOLOGY
- HISTORICAL GLEANINGS
- GENETICS AND HUMAN DEVELOPMENT
- MOLECULAR BIOLOGY OF HUMAN DEVELOPMENT
- DESCRIPTIVE TERMS IN EMBRYOLOGY
- CLINICALLY ORIENTED PROBLEMS
- Bibliography and Suggested Reading
- 2. First Week of Human Development
- Chapter Outline
- GAMETOGENESIS
- MEIOSIS
- SPERMATOGENESIS
- OOGENESIS
- COMPARISON OF GAMETES
- UTERUS, UTERINE TUBES, AND OVARIES
- FEMALE REPRODUCTIVE CYCLES
- OVARIAN CYCLE
- MENSTRUAL CYCLE
- TRANSPORTATION OF GAMETES
- MATURATION OF SPERMS
- VIABILITY OF GAMETES
- SEQUENCE OF FERTILIZATION
- CLEAVAGE OF ZYGOTE
- FORMATION OF BLASTOCYST
- SUMMARY OF FIRST WEEK
- CLINICALLY ORIENTED PROBLEMS
- Bibliography and Suggested Reading
- 3. Second Week of Human Development
- Chapter Outline
- COMPLETION OF IMPLANTATION OF BLASTOCYST
- FORMATION OF AMNIOTIC CAVITY, EMBRYONIC DISC, AND UMBILICAL VESICLE
- DEVELOPMENT OF CHORIONIC SAC
- SUMMARY OF IMPLANTATION
- SUMMARY OF SECOND WEEK
- CLINICALLY ORIENTED PROBLEMS
- Bibliography and Suggested Reading
- 4. Third Week of Human Development
- Chapter Outline
- GASTRULATION: FORMATION OF GERM LAYERS
- PRIMITIVE STREAK
- NOTOCHORDAL PROCESS AND NOTOCHORD
- Allantois
- NEURULATION: FORMATION OF NEURAL TUBE
- DEVELOPMENT OF SOMITES
- DEVELOPMENT OF INTRAEMBRYONIC COELOM
- EARLY DEVELOPMENT OF CARDIOVASCULAR SYSTEM
- DEVELOPMENT OF CHORIONIC VILLI
- SUMMARY OF THIRD WEEK
- CLINICALLY ORIENTED PROBLEMS
- Bibliography and Suggested Reading
- 5. Fourth to Eighth Weeks of Human Development
- Chapter Outline
- PHASES OF EMBRYONIC DEVELOPMENT
- FOLDING OF EMBRYO
- GERM LAYER DERIVATIVES
- CONTROL OF EMBRYONIC DEVELOPMENT
- HIGHLIGHTS OF THE FOURTH TO EIGHTH WEEKS
- ESTIMATION OF EMBRYONIC AGE
- SUMMARY OF FOURTH TO EIGHTH WEEKS
- CLINICALLY ORIENTED PROBLEMS
- Bibliography and Suggested Reading
- 6. Fetal Period: Ninth Week to Birth
- Chapter Outline
- ESTIMATION OF FETAL AGE
- HIGHLIGHTS OF THE FETAL PERIOD
- EXPECTED DATE OF DELIVERY
- FACTORS INFLUENCING FETAL GROWTH
- PROCEDURES FOR ASSESSING FETAL STATUS
- SUMMARY OF FETAL PERIOD
- CLINICALLY ORIENTED PROBLEMS
- Bibliography and Suggested Reading
- 7. Placenta and Fetal Membranes
- Chapter Outline
- PLACENTA
- PARTURITION
- UMBILICAL VESICLE
- ALLANTOIS
- MULTIPLE PREGNANCIES
- SUMMARY OF PLACENTA AND FETAL MEMBRANES
- NEONATAL PERIOD
- CLINICALLY ORIENTED PROBLEMS
- Acknoweldgement
- Bibliography and Suggested Reading
- 8. Body Cavities, Mesenteries, and Diaphragm
- Chapter Outline
- EMBRYONIC BODY CAVITY
- DEVELOPMENT OF DIAPHRAGM
- SUMMARY OF DEVELOPMENT OF BODY CAVITIES, MESENTERIES, AND DIAPHRAGM
- CLINICALLY ORIENTED PROBLEMS
- Bibliography and Suggested Reading
- 9. Pharyngeal Apparatus, Face, and Neck
- Chapter Outline
- PHARYNGEAL ARCHES
- PHARYNGEAL POUCHES
- PHARYNGEAL GROOVES
- PHARYNGEAL MEMBRANES
- DEVELOPMENT OF THYROID GLAND
- DEVELOPMENT OF TONGUE
- DEVELOPMENT OF SALIVARY GLANDS
- DEVELOPMENT OF FACE
- DEVELOPMENT OF NASAL CAVITIES
- DEVELOPMENT OF PALATE
- SUMMARY OF PHARYNGEAL APPARATUS, FACE, AND NECK
- CLINICALLY ORIENTED PROBLEMS
- Bibliography and Suggested Reading
- 10. Respiratory System
- Chapter Outline
- RESPIRATORY PRIMORDIUM
- DEVELOPMENT OF LARYNX
- DEVELOPMENT OF TRACHEA
- DEVELOPMENT OF BRONCHI AND LUNGS
- SUMMARY OF RESPIRATORY SYSTEM
- CLINICALLY ORIENTED PROBLEMS
- Bibliography and Suggested Reading
- 11. Alimentary System
- Chapter Outline
- FOREGUT
- MIDGUT
- HINDGUT
- MORPHOGENESIS OF GUT CELLS AND MICROSTRUCTURE
- ENTERIC NERVOUS SYSTEM
- SUMMARY OF ALIMENTARY SYSTEM
- CLINICALLY ORIENTED PROBLEMS
- Bibliography and Suggested Reading
- 12. Urogenital System
- Chapter Outline
- DEVELOPMENT OF THE URINARY SYSTEM
- DEVELOPMENT OF SUPRARENAL GLANDS
- DEVELOPMENT OF GENITAL SYSTEM
- DEVELOPMENT OF EXTERNAL GENITALIA
- DEVELOPMENT OF INGUINAL CANALS
- RELOCATION OF TESTES AND OVARIES
- SUMMARY OF UROGENITAL SYSTEM
- CLINICALLY ORIENTED PROBLEMS
- Bibliography and Suggested Reading
- 13. Cardiovascular System
- Chapter Outline
- EARLY DEVELOPMENT OF HEART AND BLOOD VESSELS
- LATER DEVELOPMENT OF HEART
- BIRTH DEFECTS OF HEART AND GREAT VESSELS
- DERIVATIVES OF PHARYNGEAL ARCH ARTERIES
- FETAL AND NEONATAL CIRCULATION
- DEVELOPMENT OF LYMPHATIC SYSTEM
- SUMMARY OF CARDIOVASCULAR SYSTEM
- CLINICALLY ORIENTED PROBLEMS
- Bibliography and Suggested Reading
- 14. Skeletal System
- Chapter Outline
- DEVELOPMENT OF BONE AND CARTILAGE
- DEVELOPMENT OF JOINTS
- DEVELOPMENT OF AXIAL SKELETON
- DEVELOPMENT OF APPENDICULAR SKELETON
- SUMMARY OF SKELETAL SYSTEM
- CLINICALLY ORIENTED PROBLEMS
- Bibliography and Suggested Reading
- 15. Muscular System
- Chapter Outline
- DEVELOPMENT OF SKELETAL MUSCLE
- DEVELOPMENT OF SMOOTH MUSCLE
- DEVELOPMENT OF CARDIAC MUSCLE
- SUMMARY OF MUSCULAR SYSTEM
- CLINICALLY ORIENTED PROBLEMS
- Bibliography and Suggested Reading
- 16. Development of the Limbs
- Chapter outline
- Early Stages of Limb Development
- FINAL STAGES OF LIMB DEVELOPMENT
- BIRTH DEFECTS OF LIMBS
- SUMMARY OF LIMB DEVELOPMENT
- CLINICALLY ORIENTED PROBLEMS
- Bibliography and Suggested Reading
- 17. Nervous System
- Chapter Outline
- DEVELOPMENT OF THE NERVOUS SYSTEM
- DEVELOPMENT OF THE SPINAL CORD
- DEVELOPMENT OF BRAIN
- BIRTH DEFECTS OF THE BRAIN
- DEVELOPMENT OF PERIPHERAL NERVOUS SYSTEM
- DEVELOPMENT OF AUTONOMIC NERVOUS SYSTEM
- SUMMARY OF NERVOUS SYSTEM
- CLINICALLY ORIENTED PROBLEMS
- Bibliography and Suggested Reading
- 18. Development of Eyes and Ears
- Chapter Outline
- DEVELOPMENT OF EYES AND RELATED STRUCTURES
- DEVELOPMENT OF EARS
- SUMMARY OF EYE DEVELOPMENT
- SUMMARY OF EAR DEVELOPMENT
- CLINICALLY ORIENTED PROBLEMS
- Bibliography and Suggested Reading
- 19. Integumentary System
- Chapter Outline
- DEVELOPMENT OF SKIN AND APPENDAGES
- SUMMARY OF INTEGUMENTARY SYSTEM
- CLINICALLY ORIENTED PROBLEMS
- Bibliography and Suggested Reading
- 20. Human Birth Defects
- Chapter Outline
- CLASSIFICATION OF BIRTH DEFECTS
- TERATOLOGY: STUDY OF ABNORMAL DEVELOPMENT
- BIRTH DEFECTS CAUSED BY GENETIC FACTORS
- BIRTH DEFECTS CAUSED BY ENVIRONMENTAL FACTORS
- BIRTH DEFECTS CAUSED BY MULTIFACTORIAL INHERITANCE
- SUMMARY OF BIRTH DEFECTS
- CLINICALLY ORIENTED PROBLEMS
- Bibliography and Suggested Reading
- 21. Common Signaling Pathways Used During Development
- Chapter Outline
- INTERCELLULAR COMMUNICATION
- MORPHOGENS
- PROTEIN KINASES
- NOTCH-DELTA PATHWAY
- TRANSCRIPTION FACTORS
- EPIGENETICS
- STEM CELLS: DIFFERENTIATION VERSUS PLURIPOTENCY
- SUMMARY OF COMMON SIGNALING PATHWAYS USED DURING DEVELOPMENT
- Bibliography and Suggested Reading
- Appendix. Discussion of Clinically Oriented Problems
- Chapter 1
- Chapter 2
- Chapter 3
- Chapter 4
- Chapter 5
- Chapter 6
- Chapter 7
- Chapter 8
- Chapter 9
- Chapter 10
- Chapter 11
- Chapter 12
- Chapter 13
- Chapter 14
- Chapter 15
- Chapter 16
- Chapter 17
- Chapter 18
- Chapter 19
- Chapter 20
- Index
- Confidence is ClinicalKey
- No. of pages: 522
- Language: English
- Edition: 12
- Published: August 1, 2024
- Imprint: Elsevier
- Paperback ISBN: 9780443119484
- Paperback ISBN: 9780443116988
- eBook ISBN: 9780443117404
MT
Mark G. Torchia
Affiliations and expertise
Associate Professor, Department of Surgery, Associate Professor, Department of Human Anatomy and Cell Sciences, Max Rady College of Medicine, Rady Faculty of Health Sciences; Vice-Provost (Teaching and Learning, University of Manitoba, Winnipeg, Manitoba, CanadaTP
T. V. N. Persaud
Affiliations and expertise
Professor Emeritus and Former Head, Department of Human Anatomy and Cell Science, Professor of Pediatrics and Child Health, Associate Professor of Obstetrics, Gynecology, and Reproductive Sciences Max Rady College of Medicine, Rady Faculty of Health Sciences; Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada