The Biogenesis of Mitochondria

List of Contributors

Preface

Introduction

Part I. Mitochondrial Transcription: The Mechanisms and Products, the Role of Mitochondrial DNA and Some Genetic Aspects

Molecular Approaches to the Dissection of the Mitochondrial Genome in HeLa Cells

The DNA-Dependent RNA Polymerases from Yeast Mitochondria

A Mitochondrial DNA-Directed RNA Polymerase from Yeast Mitochondria

The DNA-Dependent RNA Polymerase from Rat-Liver Mitochondria

Expression of the Mitochondrial Genome in Wild Type and in an Extranuclear Mutant of Neurospora crassa

Transcription of mtDNA by Mitochondrial RNA Polymerase from Xenopus laevis

Effect of Rifampicin on Iriacromolecular Synthesis in Rat-Liver Mitochondria

Characterization of Yeast Grande and Petite Mitochondrial DNA by Hybridization and Physical Techniques

Elongation Factors for Organellar Protein Synthesis in Chlorella vulgaris

Synthesis and Processing of Mitochondrial Ribosomal RNA in Wild Type and Poky Strain of Neurospora crassa

Biogenesis of Mitochondria from Artemia salina Cysts and the Transcription In Vitro of the DNA

Structure of Petite mtDNA; Prospects for Mitochondrial Gene Isolation, Mapping and Sequencing

The Purification of Mitochondrial Genes Using Petite Mutants of Yeast

Interaction of Mitochondrial Protein Synthesis on the Regulation of Gene Activity in Saccharomyces cerevisiae

Isolation, Purification, Physico-Chemical Characterization and Recombination of Yeast Mitochondrial DNA Segments Conferring Resistance either to Chloramphenicol or to Erythromycinm

Mitochondrial Genetic Factors in the Cellular Response to Chlorimipramine in Saccharomyces cerevisiae

Mitochondrial Genetics

Mitochondrial Genes and ATP-Synthetase

Characterization of a Respiration Competent, Oligomycin Resistant Mutant of Schizosaccharomyces Pombe Lacking Cytochrome b-566 but still Binding Antimycin

Mitochondrial Enzymes in Man-Mouse Hybrid Cells

Temperature-Dependent Changes in Levels of Multiple-Length Mitochondrial DNA in Cells Transformed by a Thermosensitive Mutant of Rous Sarcoma Virus

Propagation and Recombination of Parental mtDNAs in Hybrid Cells

Mitochondrial Mutations in Paramecium: Phenotypical Characterization and Recombination

Part II. Characteristics of the Mitochondrial Protein Synthetic Machinery

Mutations Affecting Mitochondrial Ribosomes in Yeast

Evidence of Involvement of Mitochondrial Polysomes and Messinger RNA in Synthesis of Organelle Proteins

Mitochondrial Polysomes from Neurospora crassa

Nascent Polypeptide Chains on Mitochondrial Ribosomes and Their Integration into the Inner Mitochondrial Membrane

Analysis of Mitoribosomes from Tetrahymena by Polyacrylamide Gel Electrophoresis and Electron Microscopy

Fine Structure of Mitochondrial Ribosomes of Locust Flight Muscle

The Structure, Composition and Function of 55S Mitochondrial Ribosomes

Physicochemical and Functional Characterization of the 55S Ribosomes from Rat-Liver Mitochondria

Characterization of the Monomer Form of Rat-Liver Mitochondrial Ribosomes and Its Activity in Poly U-Directed Polyphenylalanine Synthesis

RNA from Mitochondrial Ribosomes of Locusta Migratoria

Coding Degeneracy in Mitochondria

On the Sensitivity of Mammalian Mitochondrial Protein Synthesis to Inhibition by the Macrolide Antibiotics

Part III. Synthesis of Mitochondrial Proteins Mitochondrial Products of Yeast ATPase and Cytochrome Oxidase

Initiation, Identification and Integration of Mitochondrial Proteins

The Biosynthesis of Mitochondrial Ribosomes in Saccharomyces Cerevisiae

Cooperation of Mitochondrial and Cytoplasmic Protein Synthesis in the Formation of Cytochrome C Oxidase

Studies on the Control of Mitochondrial Protein Synthesis in Yeast

The Biosynthesis of Mitochondrial Cytochromes

Biogenesis of Cytochrome b in Neurospora crassa

Precursor Proteins of Cytochrome C Oxidase in Cytochrome C Oxidase Deficient Copper-Depleted Neurospora

Antibodies to Subunits of Cytochrome C Oxidase and Their Relation to Precursor Proteins of this Enzyme

Cytoplasmic Ribosomes Associated with Yeast Mitochondria

Mitochondrial Synthesis of Glycoproteins and Surface Properties of Mitochondrial Membranes

Membrane Structure and Mitochondrial Biogenesis

Lecithin Formation in Phospholipase C-Treated Rat-Liver Mitochondria

Concluding Remarks