Skip to main content
Elsevier

Systems Biology of Addiction Medicine

Gut–Brain Axis, OMICS, and Molecular Technologies

  • 1st Edition - May 1, 2027
  • Latest edition
  • Editors: Mohammad Shabani, Silvia Turroni, Mohammad Navid Ebrahimi, Mohammad Banazadeh
  • Language: English

Systems Biology of Addiction Medicine: Gut–Brain Axis, OMICS, and Molecular Technologies is a cutting-edge reference that explores the complex neurobiological mechanisms u… Read more

Description

Systems Biology of Addiction Medicine: Gut–Brain Axis, OMICS, and Molecular Technologies is a cutting-edge reference that explores the complex neurobiological mechanisms underlying substance use disorders (SUD). This volume emphasizes the importance of the microbiome-gut-brain axis (MGBA), multi-OMICS approaches, and molecular tools such as CRISPR-Cas9 in advancing addiction research. It addresses the urgent need for integrated frameworks to understand the bidirectional communication between the gut and brain in disorders like nicotine, opioid, alcohol, neurostimulant, and cannabis use. The book synthesizes foundational knowledge with recent developments, offering detailed methodologies, case studies, and translational strategies that bridge basic science and clinical application. Its comprehensive scope makes it invaluable for researchers and clinicians seeking to develop personalized, evidence-based therapies for SUDs. The contents include dedicated sections on the MGBA's role across various substances, detailed chapters on multi-OMICS, SNP, and immunotherapy techniques, and discussions on emerging molecular technologies like CRISPR. Each chapter combines literature reviews, recent advances, and practical applications, supported by schematic figures designed for clarity. The volume aims to empower neuroscientists, psychiatrists, pharmacologists, and biotech professionals with the latest scientific insights and tools to address the global challenge of addiction. By fostering interdisciplinary understanding, this resource supports hypothesis generation, research innovation, and the development of targeted interventions to improve patient outcomes.

Key features

  • Integrates gut–brain axis, OMICS, and molecular technologies for addiction research
  • Provides mechanistic models and translational protocols for SUD therapies
  • Highlights recent advances in multi-OMICS, SNP, CRISPR, and immunotherapy
  • Bridges neurobiology with microbiome science for personalized medicine
  • Offers global case studies and innovative research frameworks

Readership

Neuroscientists, psychiatrists, and pharmacologists

Table of contents

Part 1: The Gut-Brain-Axis

1. The role of the Microbiome–Gut–Brain Axis in nicotine use disorder

2. The role of the Microbiome–Gut–Brain Axis in opioid use disorder

3. The role of the Microbiome–Gut–Brain Axis in alcohol use disorder

4. The role of the Microbiome–Gut–Brain Axis in neurostimulant use disorder

5. The role of the Microbiome–Gut–Brain Axis in cannabis use disorder

Part 2: The role of modern central dogma of molecular biology-related methods in addiction

6. Multi-OMICS methods

7. Immunotherapies and vaccines

8. Single nucleotide polymorphisms (SNP) methods

9. Implications for CRISPR-Cas9

Product details

  • Edition: 1
  • Latest edition
  • Published: May 1, 2027
  • Language: English

About the editors

MS

Mohammad Shabani

Professor Mohammad Shabani acquired a PhD in 2010 from the Shahid Beheshti University of Medical Sciences. He earned a fellowship training in calcium imaging and intracellular recording at the Copenhagen University (Department of drug design and pharmacology) in 2018. Professor Shabani earned the honor of the full professorship of Kerman Medical University since the second half of 2018. He is an academic member in the Department of Neuroscience in Kerman Neuroscience Research Center (KNRC) (since 2005). He has been the Chair of Research community of KNRC for 8 years. Professor Shabani chaired the intracellular recording lab of KNRC between 2011 and 2023. So far, Professor Shabani has contributed to authoring more than 150 papers in prestigious journals and authoring one book.

Affiliations and expertise
Professor, Department of Neuroscience, Kerman Neuroscience Research Center, Kerman University of Medical Sciences, Kerman, Iran

ST

Silvia Turroni

Prof. Silvia Turroni is an expert in the field of Microbiome-Gut-Brain-Axis and currently serves an Associate Professor of the Department of Pharmacy and Biotechnology in the University of Bologna, Italy.
Affiliations and expertise
Associate Professor, Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy

ME

Mohammad Navid Ebrahimi

Dr. Mohammad Navid Ebrahimi completed his PhD in Neuroscience at Kerman Neuroscience Research Center. He has been working as a researcher since his Masters studies in the field of Medical Physiology. He currently serves as an Assistant Professor in the Department of Psychiatry at Kerman University of Medical Sciences, where he also contributes to the Neuroscience Research Center. His main research interests are addiction and cognitive impairments.

Affiliations and expertise
Assistant Professor, Department of Psychiatry, Kerman University of Medical Sciences, Kerman, Iran

MB

Mohammad Banazadeh

Dr. Mohammad Banazadeh earned his PharmD. degree from Kerman University of Medical Sciences in 2019. Since then he has been working as a Research Assistant in Kerman Neuroscience Research Center and Pharmaceutical Sciences and Cosmetic Products Research Center. He is enthusiastic of science especially of Neuroscience, which has been his favourite topic since he was young.

Affiliations and expertise
Kerman University of Medical Sciences, Iran