
Supercritical CO2 Extraction
From Basic Principles to Industrial Applications
- 1st Edition - March 15, 2026
- Authors: Ivana Lukić, Stoja Milovanović, Marko Stamenić
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 3 3 5 3 4 - 1
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 3 3 5 3 5 - 8
Supercritical fluid extraction (SFE), with supercritical carbon dioxide (scCO2) as the most used fluid, is the first and arguably best-known application in the field, as well as… Read more

Supercritical fluid extraction (SFE), with supercritical carbon dioxide (scCO2) as the most used fluid, is the first and arguably best-known application in the field, as well as the first area where supercritical fluid technology has found an established industrial application. Today, scCO2 extraction is commercially applied in industries such as food (decaffeination of coffee and tea; extraction of hops, herbs, and spices; recovery of flavours and antioxidants; de-oiling of press cakes etc), pharmaceutical (extraction of herbal medicines), cosmetics (active ingredients for cosmetic preparations, fragrances). This book systematizes current knowledge in the field of scCO2 extraction. Beginning with a useful background introduction to supercritical CO2 and a summary of the fundamentals of supercritical fluids, the authors then clearly outline the ScCO2 extraction process and provide a range of key examples of its usage, such as extraction from plant, alternative (non-plant), agricultural and food by-products. Modelling approaches and scale-up guidelines are then presented, before the closing chapters look at integrated process, industrial applications, and examples of transition from research to industry, such as coffee decaffeination. Supercritical CO2 Extraction: From Basic Principles to Industrial Applications is written primarily for research and development scientists and masters or PhD students in chemical engineering, but also closely related areas of biotechnology, food engineering and technology, pharmaceutical chemistry, industrial and process engineering
- Comprehensive and detailed overview of supercritical CO2 extraction of bioactive components from natural sources
- Moves methodically through the basic background and principles of scCO2 extraction, to chapters on practical applications in various industrial settings that are poorly covered in existing literature
- Provides guidelines for scale-up and modelling for industrial application of the scCO2 extraction process
- Including examples of successful transition from research to industry usage such as coffee decaffeination
Research and development scientists and masters or PhD students in chemical engineering, but also closely related areas of biotechnology, food engineering and technology, pharmaceutical chemistry, industrial and process engineering.
1. Introduction
2. Fundamentals of supercritical CO2
3. ScCO2 extraction process
4. ScCO2 extraction from different plant parts material
5. ScCO2 extraction from agricultural and food by-products
6. ScCO2 extraction from algae, lichen, and fungi
7. ScCO2 extraction from alternative (non-plant) resources
8. Modelling of scCO2 extraction
9. Scale-up of scCO2 extraction
10. Integrated process of scCO2 extraction and supercritical impregnation of extracts
11. Industrial application of ScCO2 extraction
12. Examples of ScCO2 extraction transition from laboratory to industry on Cannabis sativa
13. Future perspectives and challenges
2. Fundamentals of supercritical CO2
3. ScCO2 extraction process
4. ScCO2 extraction from different plant parts material
5. ScCO2 extraction from agricultural and food by-products
6. ScCO2 extraction from algae, lichen, and fungi
7. ScCO2 extraction from alternative (non-plant) resources
8. Modelling of scCO2 extraction
9. Scale-up of scCO2 extraction
10. Integrated process of scCO2 extraction and supercritical impregnation of extracts
11. Industrial application of ScCO2 extraction
12. Examples of ScCO2 extraction transition from laboratory to industry on Cannabis sativa
13. Future perspectives and challenges
- Edition: 1
- Published: March 15, 2026
- Language: English
IL
Ivana Lukić
Ivana Lukić is a Senior Research Associate at the Faculty of Technology and Metallurgy, where she received her PhD in Chemical Engineering in 2015. Her early career research interest was mainly in biodiesel production from renewable and waste feedstock. Later, her research focus shifted toward the field of supercritical fluids applications, primarily supercritical carbon dioxide (scCO2), including extractions from plant material, preparation of aerogels and impregnation of polymer carriers with bioactive components. Lukic is the author of 32 publications in international journals, 2 chapters in international and 1 in national books, and 3 technical solutions. Her published articles have over 950 citations with a h-index of 16 (source: Scopus 2023).
Affiliations and expertise
Faculty of Technology and Metallurgy, University of Belgrade, SerbiaSM
Stoja Milovanović
Stoja Milovanović is a Senior Research Associate at the Faculty of Technology and Metallurgy, where she received her PhD in Chemical Engineering in 2015. Key areas of her expertise are the utilization of supercritical carbon dioxide (scCO2) for the isolation of bioactive components from plant materials, aerogels preparation, polymer foaming, and polymer impregnation with bioactive components. During 2021-2023 she was a visiting researcher at the Łukasiewicz Research Network- New Chemical Syntheses Institute, Poland. Milovanovic has published more than 47 articles that have over 1000 citations with a h-index of 19 (source: Scopus 2023). She has published 4 book chapters, 4 registered national patents, 2 national patent applications, and 1 international patent application.
Affiliations and expertise
Faculty of Technology and Metallurgy, University of Belgrade, SerbiaMS
Marko Stamenić
Marko Stamenić is an Assistant Professor at the Department of Organic Chemical Technology and Polymer Engineering, Faculty of Technology and Metallurgy, University of Belgrade, Serbia where he received his PhD in Chemical Engineering in 2010. The subject of his scientific and research work are processes under high pressures, supercritical fluids, Fischer-Topsch synthesis and mathematical modeling. He participated in the development of two mathematical models for the process of supercritical extraction which represent the “state of the art” in this field and contribute to a better understanding of the phenomenology of this process. Stamenic is the author of 26 papers in international scientific journals, several chapters in books/monographs, technical solutions and patents. According to the scientific database Scopus, Marko Stamenić's works were cited over 1000 times with a h-index of 17.
Affiliations and expertise
Assistant Professor, Department of Organic Chemical Technology and Polymer Engineering, Faculty of Technology and Metallurgy, University of Belgrade, Serbia