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Books in Medicinal chemistry

101-110 of 110 results in All results

Inorganic Chemistry

  • 1st Edition
  • March 26, 1997
  • Thomas W. Swaddle
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 5 3 4 6 8 - 8
This book addresses the question, What is inorganic chemistry good for? rather than the more traditional question, How can we develop a theoretical basis for inorganic chemistry from sophisticated theories of bonding? The book prepares students of science or engineering for entry into the multi-billion-dollar inorganic chemical and related industries, and for rational approaches to environmental problems such as pollution abatement, corrosion control, and water treatment. A much expanded and updated revision of the 1990 text, Applied Inorganic Chemistry (University of Calgary Press), Inorganic Chemistry covers topics including atmospheric pollution and its abatement, water conditioning, fertilizers, cement chemistry, extractive metallurgy, metallic corrosion, catalysts, fuel cells and advanced batter technology, pulp and paper production, explosives, supercritical fluids, sol-gel science, materials for electronics, and superconductors. Though the book waswritten as a textbook for undergraduates with a background of freshman chemistry, it will also be a valuable sourcebook for practicing chemists, engineers, environmental scientists, geologists, and educators.

Alkaloids: Chemical and Biological Perspectives

  • 1st Edition
  • Volume 10
  • May 20, 1996
  • S.W. Pelletier
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 5 2 6 9 9 - 7
Volume 10 of this series presents four timely reviews. Chapter 1 provides a fascinating account of the history of alkaloid discovery in Australia beginning with the isolation of the first alkaloid from an Australian plant, the Tasmanian sassafras (Atherosperma moschatum), by Zeyer in 1861. Also included is a comprehensive survey of alkaloid-bearing plants, and a section dealing with detection, estimation, extraction, and work-up procedures for alkaloids.Chapter 2 provides a comprehensive update to the chapter on "Pyridine and Piperidine Alkaloids" which appeared in volume 3 of this series. The focus of this chapter is on new alkaloids isolated, biosynthesis, and biological properties.Chapter 3 looks at "3-Alkylpiperidine Alkaloids Isolated from Marine Sponges in the Order Haplosclerida". Studies over the past thirty years have shown that sponges are a rich source of alkaloids. Many of these sponge alkaloids are related to each other by the presence of a 3-alkylpiperidine moiety in their structures and it happens that the sponges that have been reported to contain 3-alkylpiperidine alkaloids are all in the order Haplosclerida.Chapter 4 reviews &bgr;-carboline and isoquinoline alkaloids which are pharmacologically some of the most significant marine natural products. This chapter treats the isolation, structure elucidation, synthesis, biosynthesis, and pharmacological activity of these alkaloids.

The Chemistry of C-Glycosides

  • 1st Edition
  • Volume 13
  • December 1, 1995
  • D.E. Levy + 1 more
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 5 2 9 0 1 - 1
In recent years C-glycoside chemistry has been one of the main topics in carbohydrate chemistry, not only because of the synthetic challenges posed, but also because C-glycosides have the potential to serve as carbohydrate analogues resistant to metabolic processes. Consequently, this class of compounds is currently receiving much interest as a potential source of therapeutic agents for clinical use. This book provides a broad coverage of the various synthetic methods available for the preparation of C-glycosides, and illustrates the interesting breadth of connections between carbohydrate chemistry and modern general synthetic organic chemistry by including topics such as transition-metal catalysis, radical chemistry, cycloaddition and rearrangement processes. In addition, in the final chapter of the book, the syntheses of C-di and trisaccharides reported through 1994 are reviewed. This well organised account of the synthetic chemistry in this field will prove to be very valuable to a wide range of researchers and advanced students, both as an introduction to the topic and for reference.

Annual Reports in Medicinal Chemistry

  • 1st Edition
  • Volume 30
  • October 10, 1995
  • James A. Bristol + 2 more
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 5 8 3 7 4 - 7
Praise for the Series:"This series is one of the very few annual publications which justify the title of an absolute must for the pharmacologist, chemist, or physician who is interested in the chemistry of drug development."--Enzymologia"This book is strongly recommended for researchers, teachers, students, administrators - in short, anyone whose interests impinge on medicinal chemistry. In view of the work's documented reference value, it is a must for inlusion in the scientist's personal library."--Journal of Medicinal Chemistry"All topics are covered in sufficient depth, with extensive references, to allow either the specialist or the novice to be informed of the latest developments in a particular area of medicinal chemistry."--Norman Gilman, Hoffmann-La Roche, Inc, in the JOURNAL OF PHARMACEUTICAL SCIENCESAdvances in Medicinal Chemistry continues to provide timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies.

Annual Reports in Medicinal Chemistry

  • 1st Edition
  • Volume 29
  • October 3, 1994
  • William K. Hagmann + 6 more
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 5 8 3 7 3 - 0
This serial continues to combine regular updates of significant research in medicinal chemistry with emerging research in biological science destined to impact the discovery and development of new medicinal agents.

Case Presentations in Chemical Pathology

  • 1st Edition
  • October 19, 1993
  • Martin Crook
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 8 3 8 2 - 4
Case Presentations in Chemical Pathology is a compilation of medical records with clinical history, diagnosis, and recommended treatment. It discusses the symptoms and causes of the disease being investigated. It provides sample of laboratory results that is correlated to a possible malady. Some of the topics covered in the book are the ethanol-related liver problem; definition of hyperprolactinaemia; explanation of abnormal plasma magnesium presence in the blood; enzyme defect in acute intermittent porphyria; causes of elevated ketones in a patient’s blood and urine; and description of androgen insensitivity syndrome. The classification and clinical diagnoses of hypercalcaemia are fully covered. The definition and symptoms of Conn’s syndrome are discussed in detail. The text describes in depth the causes of euthyroid hyperthyroxinaemia. The causes of hypermagnesaemia are completely presented. A chapter is devoted to the origins of respiratory alkalosis and hyponatraemia. The book can provide useful information to doctors, students, and researchers.

Natural Products

  • 2nd Edition
  • December 13, 1991
  • Raphael Ikan
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 5 1 2 4 2 - 6
This new edition has been updated to include the following: The use of biomarkers (organic compounds in the geospherical record with carbon skeletons) reflecting the upsurge in geoporphyrin research primarily due to MS, yeast RNA nucleic acid studies: reversed-phase HPLC of amino acids; brewing industry applications (HPLC evaluation of carotenoids in orange juice and of "debittered" citrus); HPTLC of carbohydrates; synthesis of a sweetening agent from citrus peels, synthesis and degradation of alkaloids and of sterols, GC/MS uses with sterols, petroleum products, and aromatic constituents of wine and grape juice, flash chromatography of essential oils, optical purity of enantiomers affecting flavors, fragrances, and pheromones, as well as studies of lattice inclusion compounds 1H- and 13C-NMR, MS, IR and UV data are presented for most natural products.