Books in Life sciences

Regulatory Aspects of Carcinogenesis and Food Additives: The Delaney Clause

1st Edition
December 2, 2012
Frederick Coulston
English
eBook
9 7 8 0 3 2 3 1 5 1 0 1 6

Regulatory Aspects of Carcinogenesis and Food Additives: The Delaney Clause is composed of papers and discussions presented in the seventh meeting of the International Academy of Environmental Safety regarding the philosophy of the Delaney Clause. The Delaney Clause became a part of the Food and Drug Law in 1958. It states in part “that no additive shall be deemed to be safe if it is found to induce cancer when ingested by man or animal, or if it is found after tests which are appropriate for evaluation of safety of food additives to induce cancer in man or animal”. This book covers the different views of the meeting’s participants on the interpretation of the Delaney Clause. It presents list of points that should be considered in making decisions with respect to safety. Many other factors that should be taken into consideration are also discussed in this reference.

Developmental Regulation

1st Edition
December 2, 2012
Stuart Coward
English
eBook
9 7 8 0 3 2 3 1 5 8 0 2 2

Developmental Regulation: Aspects of Cell Differentiation draws together some studies which are directed toward the orderly changes in cell phenotypes that are understood to be developmental in nature. Organized into nine chapters, the book begins with a concise overview of the studies on molecular synthesis during early development. It then addresses the developmental regulation in cotton seed embryogenesis and germination; relation of hormonal regulation to the possible control of RNA and protein biosynthesis; transitions in differentiation by the cellular slime molds; and interrelationships of genes, enzymes, structures, and phenotypes in morphogenesis. It also explains the colony differentiation in green algae; cytology of developing vertebrate skeletal muscle; some comparative aspects of cardiac and skeletal myogenesis; and differentiation of cartilage in the limb.

Prostaglandin Research

1st Edition
December 2, 2012
Pierre Crabbe
English
eBook
9 7 8 0 3 2 3 1 4 9 5 1 8

Prostaglandin Research reviews the status of prostaglandin research, with particular emphasis on chemistry. This book highlights the role of scientific research in society in attempting to find drugs, with potential application to therapy, the chief impetus for prostaglandin research. This volume is organized into seven chapters and begins with an overview of the origin and properties of prostaglandins and then outlines the stage of research in the area of biosynthesis of natural entities, especially endoperoxides and thromboxanes. The reader is then introduced to a rich source of natural prostaglandins, the gorgonian Plexaura homomalla, and the pharmacology of prostaglandins. The physical methods used in prostaglandin research are considered, along with the chemistry of natural and modified prostaglandins. This book is aimed at experts in the field, as well as scientists with a general interest in chemistry and biology.

Vascular Smooth Muscle: Metabolic, Ionic, and Contractile Mechanisms

1st Edition
December 2, 2012
M.F. III Crass
English
eBook
9 7 8 0 3 2 3 1 5 9 8 7 6

Vascular Smooth Muscle: Metabolic, Ionic, and Contractile Mechanisms addresses the vascular smooth muscle function by describing plasma lipoprotein structure, synthesis, and transport in relation to the concepts of altered vascular smooth muscle lipid metabolism leading to the genesis of atherosclerotic disease. This book is organized into six chapters and begins with an introduction to the complexities of energy metabolism and how metabolic events can be correlated with a simultaneous quantitative assessment of smooth muscle mechanics and the contractile machinery at the molecular level. The next two chapters offer the reader a view of smooth muscle membrane properties in terms of the distribution, transport, and metabolic control of electrolytes and specific aspects of ion conductance and electrical activity. This text also explains how smooth muscle cells regulate their contractile activity through regulation of calcium ion fluxes and the interaction, at the molecular level, of calcium ions with regulatory proteins associated with the contractile apparatus. Reference is made to the relation of possible anomalies in cellular or subcellular smooth muscle metabolic and/or ionic events to the bases of certain types of vascular disease. A chapter that examines the events leading to vascular pathology in the form of atherogenesis concludes the book. This book is intended for researchers and clinicians engaged in the study of smooth muscle and related areas.

Swine Feeding and Nutrition

1st Edition
December 2, 2012
Tony Cunha
English
eBook
9 7 8 0 3 2 3 1 5 3 8 1 2

Swine Feeding and Nutrition provides detailed information on aspects of swine production. It begins with a presentation of the past, present, and future of swine industry. Then, it reviews the many factors that can affect nutrient requirements and needs. This text summarizes minerals, vitamins, proteins, amino acids, carbohydrates, fiber, fatty acids, fat, energy, water, enzymes, and antibiotics and other antimicrobial compounds in swine industry. Furthermore, it discusses the relative value of feeds for use in swine diets and the feeding requirement for baby pig, growing-finishing pigs, and the breeding herd. This book will be very valuable to beginners in swine production, established swine raisers, feed manufacturers and dealers, county agents, farm advisors and consultants, and veterinarians. Animal science and agriculture students and instructors will also find this book helpful.

Horse Feeding And Nutrition

1st Edition
December 2, 2012
Tony Cunha
English
eBook
9 7 8 0 3 2 3 1 5 6 6 2 2

Horse Feeding and Nutrition is the fourth in a series of books on animal feeding and nutrition that focuses on horse feeding and nutrition, aiming to assist in world food production. Organized into 20 chapters, the book contains basic information on horse industry, feeding problems, and importance in food production of proper horse nutrition. The introductory chapters discuss the importance of the horse industry; the art, science, and myths in feeding horses; the problems involved in supplying an adequate level of nutrients in horse rations; and the digestion of feeds. Chapters 5-10 cover concise, up-to-date summaries on macro- and micronutrients, including vitamins, minerals, protein, and water. The book goes on, examining the important interrelationships between nutrition, disease, and performance; the relative value of various feeds in horse rations; and the value of pasture and hay for horses. Chapters 15-18 focus on feeding the foal, growing horses; the performance and race horses; and the mares and stallions. The final chapters discuss purified rations for horses, antibiotics, founder, learning ability, feeding behavior, nutrient toxicity, weight equivalents, weight-unit conversion factors, and the effect of cold weather on horses. The book provides information helpful to beginners and experts in horse production. It will also be valuable for county agents, farm advisors, consultants, veterinarians, and teachers of vocational agriculture, as well as animal science students and teachers.

Fluid Environment of the Brain

1st Edition
December 2, 2012
Helen Cserr
English
eBook
9 7 8 0 3 2 3 1 5 6 8 7 5

Fluid Environment of the Brain presents the proceedings of a symposium held in Bar Harbor, Maine in September 1974 under the joint sponsorship of the Mount Desert Island Biological Laboratory and the National Cancer Institute. Contributors discuss the fluid matrix of the brain and the functional relationships among neurons, neuroglia, and their extracellular fluids in normal and pathological states. They focus on the cerebral interstitial fluid and the membranes—or barrier mechanisms—which contribute to the regulation of the physical and chemical characteristics of these fluids. This book is organized into four sections encompassing 17 chapters and begins with an overview of anatomical relationships, with special reference to the morphology of the walls around fluid compartments in the nervous tissue. The reader is then introduced to the physiology of the blood-brain barrier and the choroid plexus, as well as the exchange between the cerebrospinal fluid (CSF) and brain. Methods for determining the permeability of the blood-brain barrier are described. The book also explores amino acid transport mechanisms in the choroid plexus, distribution of hormones by CSF, and the physiological aspects of lactate and peptides in the CSF. Special consideration is given to the attempts to use CSF as a means of studying the chemistry, metabolism, and possible endocrine functions of the brain. This book is of interest to pharmacologists and clinicians, as well as physiologists and neurochemists.

Lipoxygenases and Their Products

1st Edition
December 2, 2012
Stanley Crooke
English
eBook
9 7 8 0 3 2 3 1 5 6 5 3 0

Lipoxygenases and Their Products provides a cogent summary of the advances in understanding lipoxygenases and their products, emphasizing their pharmacology and pathophysiology; regulation and structure; physiological role; and receptors and receptor antagonists. This text also reviews the literature where specific receptor antagonists (as opposed to enzymatic inhibitors) have been used to characterize the pharmacologic action and the pathophysiologic roles of some of lipoxygenase products of arachidonic acid metabolism. This book is organized into 11 chapters and begins with an overview of the biochemical, pharmacological, and pathophysiological aspects of 5-lipoxygenase products of arachidonic acid metabolism in the respiratory, cardiovascular, renal, gastrointestinal, and central nervous systems. The discussion then shifts to human 5-lipoxygenase, emphasizing this enzyme purification, stimulatory factors, and membrane translocation. The reader is methodically introduced to 5-lipoxygenase activity in rats and pigs; the potential and therapeutic value of 5-lipoxygenase inhibitors; the distribution of 15-lipoxygenase in cells or tissues; and products formed through the 15-lipoxygenase pathway. This book also considers lipoxins and third-generation peptidoleukotriene receptor antagonists, and then concludes with a summary of the physiological and pathophysiological effects of leukotrienes and lipoxins in a variety of organs. This book is of interest to scientists interested in arachidonic acid and its metabolites, to scientists engaged in drug discovery-and-develo... activities in academia and the pharmaceutical industry, and to clinicians interested in diseases associated with leukotrienes and related products.

Dry Biological Systems

1st Edition
December 2, 2012
James S. Clegg
English
eBook
9 7 8 0 3 2 3 1 5 3 8 2 9

Dry Biological Systems contains the proceedings of the 1977 American Institute of Biological Sciences symposium held in East Lansing, Michigan. Divided into seven parts encompassing 17 chapters, the book focuses on the adaptive strategy phenomenon of organisms under dry state or absence of water. The book answers several fundamental questions on dry biological systems, such as how an organism achieve a state that destroys most living systems; what adaptations permit the survival of dehydration; and what activities occur in the dry organisms. After briefly discussing the nature of intracellular water in normal cells, the book examines the ultrastructure of dry organisms, including their metabolic activities during drying, in the dry state, and during rehydration. Parts IV to VI discuss the causes of cell viability loss while in dry, as well as their ecology and enzyme reaction at reduced water activity. Several presentations are made in which freezing and dehydration as stress vectors are compared. Covered papers in the book illustrate the belief that freezing and rehydration can be considered to be the same phenomenon, particularly with respect to the state of intracellular water.

Laboratory Exercises in Developmental Biology

1st Edition
December 2, 2012
Yolanda P. Cruz
English
eBook
9 7 8 0 3 2 3 1 3 7 7 7 5

This intensive manual provides students with valuable information and insights into animal development at the organismal, cellular, and subcellular levels. The book uses both descriptive and investigative approaches that emphasize techniques, key experiments, and data analysis.

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