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8781-8790 of 14737 results in All results

Lead Compounds from Medicinal Plants for the Treatment of Cancer

  • 1st Edition
  • October 22, 2012
  • Christophe Wiart
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 3 9 8 3 7 1 - 8
  • eBook
    9 7 8 - 0 - 1 2 - 3 9 8 3 8 2 - 4
Lead Compounds from Medicinal Plants for the Treatment of Cancer is the first volume in the series, Pharmaceutical Leads from Medicinal Plants. The plant species described in this reference have been carefully selected based on pharmacological evidence and represent today’s most promising sources of natural products for the discovery of anti-cancer drugs. Containing references to primary source material, over a hundred botanical illustrations, a table of chemical structures and much more, this book is an essential starting point for cancer researchers and those involved in anti-cancer drug discovery helping you identify the best novel lead molecules for further anti-cancer drug development.

Encapsulation Technologies and Delivery Systems for Food Ingredients and Nutraceuticals

  • 1st Edition
  • October 19, 2012
  • Nissim Garti + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 8 5 7 0 9 - 1 2 4 - 6
  • eBook
    9 7 8 - 0 - 8 5 7 0 9 - 5 9 0 - 9
Improved technologies for the encapsulation, protection, release and enhanced bioavailability of food ingredients and nutraceutical components are vital to the development of future foods. Encapsulation technologies and delivery systems for food ingredients and nutraceuticals provides a comprehensive guide to current and emerging techniques.Part one provides an overview of key requirements for food ingredient and nutraceutical delivery systems, discussing challenges in system development and analysis of interaction with the human gastrointestinal tract. Processing technologies for encapsulation and delivery systems are the focus of part two. Spray drying, cooling and chilling are reviewed alongside coextrusion, fluid bed microencapsulation, microencapsulation methods based on biopolymer phase separation, and gelation phenomena in aqueous media. Part three goes on to investigate physicochemical approaches to the production of encapsulation and delivery systems, including the use of micelles and microemulsions, polymeric amphiphiles, liposomes, colloidal emulsions, organogels and hydrogels. Finally, part four reviews characterization and applications of delivery systems, providing industry perspectives on flavour, fish oil, iron micronutrient and probiotic delivery systems.With its distinguished editors and international team of expert contributors, Encapsulation technologies and delivery systems for food ingredients and nutraceuticals is an authoritative guide for both industry and academic researchers interested in encapsulation and controlled release systems.

A Comprehensive Guide to Toxicology in Preclinical Drug Development

  • 1st Edition
  • October 18, 2012
  • Ali S. Faqi
  • English
  • eBook
    9 7 8 - 0 - 1 2 - 3 8 7 8 1 6 - 8
A Comprehensive Guide to Toxicology in Preclinical Drug Development is a resource for toxicologists in industry and regulatory settings, as well as directors working in contract resource organizations, who need a thorough understanding of the drug development process. Incorporating real-life case studies and examples, the book is a practical guide that outlines day-to-day activities and experiences in preclinical toxicology. This multi-contributed reference provides a detailed picture of the complex and highly interrelated activities of preclinical toxicology in both small molecules and biologics. The book discusses discovery toxicology and the international guidelines for safety evaluation, and presents traditional and nontraditional toxicology models. Chapters cover development of vaccines, oncology drugs, botanic drugs, monoclonal antibodies, and more, as well as study development and personnel, the role of imaging in preclinical evaluation, and supporting materials for IND applications. By incorporating the latest research in this area and featuring practical scenarios, this reference is a complete and actionable guide to all aspects of preclinical drug testing.

Advances in Food and Nutrition Research

  • 1st Edition
  • Volume 66
  • October 18, 2012
  • Steve Taylor
  • English
  • eBook
    9 7 8 - 0 - 1 2 - 3 9 4 6 4 9 - 2
Advances in Food and Nutrition Research recognizes the integral relationship between the food and nutritional sciences and brings together outstanding and comprehensive reviews that highlight this relationship. Contributions detail scientific developments in the broad areas of food science and nutrition and are intended to provide those in academia and industry with the latest information on emerging research in these constantly evolving sciences.

Autophagy in Health and Disease

  • 1st Edition
  • October 16, 2012
  • Roberta A. Gottlieb
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 3 8 5 1 0 1 - 7
Autophagy in Health and Disease offers an overview of the latest research in autophagy with a translational emphasis. This publication takes scientific research in autophagy a step further and offers integrated content with advancements in autophagy from cell biology and biochemical research to clinical treatments. A necessary reference for the bookshelf of medical and scientific researchers and students, Autophagy in Health and Disease presents high quality, reputable information on autophagy, allowing the reader quick access to the most applicable information.

Eukaryotic RNases and their Partners in RNA Degradation and Biogenesis

  • 1st Edition
  • Volume 31
  • October 16, 2012
  • Guillaume Chanfreau + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 4 0 4 7 4 0 - 2
  • eBook
    9 7 8 - 0 - 1 2 - 4 0 4 7 4 5 - 7
This special issue of The Enzymes is targeted towards researchers in biochemistry, molecular and cell biology, pharmacology, and cancer. This volume discusses Eukaryotic RNases and their partners in RNA degradation and biogenesis.

Therapeutic Antibody Engineering

  • 1st Edition
  • October 16, 2012
  • William R Strohl + 1 more
  • English
  • Hardback
    9 7 8 - 1 - 9 0 7 5 6 8 - 3 7 - 4
  • eBook
    9 7 8 - 1 - 9 0 8 8 1 8 - 0 9 - 6
The field of antibody engineering has become a vital and integral part of making new, improved next generation therapeutic monoclonal antibodies, of which there are currently more than 300 in clinical trials across several therapeutic areas. Therapeutic antibody engineering examines all aspects of engineering monoclonal antibodies and analyses the effect that various genetic engineering approaches will have on future candidates. Chapters in the first part of the book provide an introduction to monoclonal antibodies, their discovery and development and the fundamental technologies used in their production. Following chapters cover a number of specific issues relating to different aspects of antibody engineering, including variable chain engineering, targets and mechanisms of action, classes of antibody and the use of antibody fragments, among many other topics. The last part of the book examines development issues, the interaction of human IgGs with non-human systems, and cell line development, before a conclusion looking at future issues affecting the field of therapeutic antibody engineering.

Commercializing the Stem Cell Sciences

  • 1st Edition
  • October 16, 2012
  • Olivia Harvey
  • English
  • eBook
    9 7 8 - 1 - 9 0 8 8 1 8 - 1 4 - 0
Promising new developments in biomedical technology such as stem cell science are widely endorsed by governments keen to reduce spiralling healthcare costs, clinicians focused on patient care, and patients demanding revolutionary new treatments. Commercializing the stem cell sciences offers a comparative analysis of the commercial methods adopted in the global stem cell industries. It seeks to establish whether there is an optimum commercial model and to examine what emerging companies can learn from their predecessors. Following an introduction to stem cell sciences and the problems involved in their commercialization, the book begins with a discussion of stem cell treatments from a global perspective, and the role of innovation in the commercialization of biotechnology in general. In the second half of the book, chapters focus on the different strategies that can be employed and their relative risks and values, before a conclusion that looks at potential new developments in the field.

The Design and Manufacture of Medical Devices

  • 1st Edition
  • October 16, 2012
  • J. Paulo Davim + 1 more
  • English
  • Hardback
    9 7 8 - 1 - 9 0 7 5 6 8 - 7 2 - 5
  • eBook
    9 7 8 - 1 - 9 0 8 8 1 8 - 1 8 - 8
Medical devices play an important role in the field of medical and health technology, and encompass a wide range of health care products. Directive 2007/47/EC defines a medical device as any instrument, apparatus, appliance, software, material or other article, whether used alone or in combination, including the software intended by its manufacturer to be used specifically for diagnostic and/or therapeutic purposes and necessary for its proper application, intended by the manufacturer to be used for human beings. The design and manufacture of medical devices brings together a range of articles and case studies dealing with medical device R&D. Chapters in the book cover materials used in medical implants, such as Titanium Oxide, polyurethane, and advanced polymers; devices for specific applications such as spinal and craniofacial implants, and other issues related to medical devices, such as precision machining and integrated telemedicine systems.

Genomic Insights into the Biology of Algae

  • 1st Edition
  • Volume 64
  • October 11, 2012
  • Gwanael Piganeau
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 3 9 1 4 9 9 - 6
  • eBook
    9 7 8 - 0 - 1 2 - 3 9 4 4 1 1 - 5
Advances in Botanical Research publishes in-depth and up-to-date reviews on a wide range of topics in plant sciences. The series features a wide range of reviews by recognized experts on all aspects of plant genetics, biochemistry, cell biology, molecular biology, physiology and ecology. This thematic volume features reviews on Genomic Insights into the Biology of Algae.

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