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Elsevier

Books in Life sciences

  • Unlocking the Secrets of Extracellular Vesicles and Exosomes

    A Journey into the Cutting-Edge Frontier of Cellular Communication
    • 1st Edition
    • Chandrashekhar Singh + 4 more
    • English
    Unlocking the secrets of extracellular vesicles and exosomes: A journey into the cutting-edge frontier of cellular communication provides a comprehensive overview of the latest advances and research on extracellular vesicles (EVs) and exosomes. The book begins with a historical introduction to the field and how this has evolved since EVs were first observed, before exploring their cellular mechanisms and approaches to study their isolation, characterization, and function. It then delves into exosomes in health and disease, considering their role across cancer, regenerative medicine, neurological disorders, and metabolic disorders, highlighting their potential as biomarkers for disease diagnosis. The book moves on to discuss cutting-edge technology for the engineering of EVs and exosomes, considering how the integration of AI, machine learning, and nanotechnology can be utilized to expand the therapeutic capabilities of EV and exosome-based applications. It then closes with chapters covering novel applications in nutraceutical and cosmetic production, and a look towards the future potential of EVs and exosomes. Unlocking the secrets of extracellular vesicles and exosomes offer a thorough exploration of EV and exosome research, covering various dimensions from basic science to clinical applications and future perspectives. It is an ideal guide for researchers working across a diverse range of disciplines, including cell biology, molecular biology, biotechnology, therapeutics, and biomedicine.

  • Lipids and Membranes: Metabolism, Lipidation, and Lipid-Protein Interactions

    • 1st Edition
    • Volume 728
    • English
    Lipids and Membranes: Metabolism, Lipidation, and Lipid-Protein Interactions, Volume 729 provides a broad snapshot of state-of-the-art methods for studying biological lipids and biomembranes. Sections in this new release cover De novo chemoenzymatic construction of lipid membranes, Photoaffinity labeling for cholesterol metabolism, Expression and Characterization of Phospholipase Cb and Ce enzymes, Assembling Retromer-coated membrane tubules for in vitro structure-function studies, Quantitative analysis of S-acylation, Inhibition of palmitoyltransferase... Exploiting protein lipidation to create peptide-based biomaterials, and much more.Additional sections discuss Optogenetic control of lipid-modifying enzyme activity using LOV domain insertions, Chemoproteomics approaches for inhibition of diacylglycerol kinases, Inhibition of sterol transfer protein function, Preparation of K-Ras4B containing synthetic modifications via expressed protein ligation, Regulation of lipin enzymes on membranes, Use of novel synthetic analogues to decipher the interactions of phosphatidic acids species, Analyzing lipid-nuclear receptor interactions, and much more.

  • Gross Pathology Atlas

    A Guide to Gross Specimens Evaluation
    • 1st Edition
    • Neda Zarrin-Khameh + 2 more
    • English
    Gross Pathology Atlas: A Guide to Gross Specimen Evaluation is a novel reference dedicated to 'gross' images. Gross pathology is the branch of pathology that deals with the examination and diagnosis of diseases through the observation of organs, tissues, and bodily fluids with the naked eye, without the aid of a microscope. It involves the examination of specimens obtained during surgery, autopsy, or biopsy. This book serves as an essential tool for diagnosing diseases. By observing macroscopic features, pathologists can identify diseases or conditions affecting various organs and tissues for example, to detect tumors, inflammation, infections, and degenerative changes. Gross pathology specimens serve as invaluable teaching aids for medical students, residents, and healthcare professionals. They provide tangible examples of disease manifestations, facilitating the understanding of pathological processes. Moreover, gross pathology specimens are essential for research purposes, allowing scientists to study disease mechanisms, develop new treatments, and advance medical knowledge.

  • Microbial Stress Biology

    • 1st Edition
    • Samiksha Joshi + 4 more
    • English
    Microbial Stress Biology offers a comprehensive understanding of the adaptation strategies of microbes at the biochemical and molecular level in response to stressful conditions, while also detailing the molecular mechanisms that enable microbial organisms to survive and persist under these adverse circumstances. The book discusses a wide array of topics related to microbial adaptation, covering fundamental biological responses to stress, microbial adaptations at cellular, genomic, and proteomic levels, as well as specific adaptations and regulations to various environmental stress factors such as pH fluctuations, chemicals, and extreme thermal conditions.Sections also highlight the application of omics technology and predictive modeling in understanding microbial stress biology for various fields, including biotechnology, medicine, bioremediation, and industrial processes. This book is an informative resource for those in microbiology, molecular biology, biotechnology, and other related fields who are searching for a better understanding of how microbes are able to sense and respond to distinct stressors at both molecular and cellular levels.

  • A Complete Guide to Hysteroscopic Myomectomy

    • 1st Edition
    • Rahul Manchanda + 2 more
    • English
    A Complete Guide to Hysteroscopy Myomectomy provides an evidence-based, comprehensive treatise on hysteroscopic myomectomy, a valuable option for treating uterine fibroids that offers a less invasive alternative to traditional surgeries like hysterectomies and laparotomies. This complete guide helps readers master how to diagnose and select the most appropriate strategy of treatment, describing all aspects of each strategy and applying the knowledge in different clinical settings. This is an essential reference for anyone in the research and medical field. It's also ideal for patients who want to understand the procedure's benefits, indications, and recovery process to make informed decisions about their treatment options.

  • Artificial Intelligence in Gastrointestinal Cancers

    • 1st Edition
    • Ganji Purnachandra Nagaraju + 2 more
    • English
    Artificial Intelligence in Gastrointestinal Cancers examines the transformative impact of AI technologies on diagnosing and treating gastrointestinal malignancies. This book explores how advanced algorithms, particularly deep learning models, enhance the analysis of medical imaging, including endoscopic, MRI, and CT scans, facilitating earlier and more accurate identification of cancers such as esophageal, stomach, colorectal, and pancreatic cancers. The content covers AI's multifaceted applications, from improving diagnostic accuracy to personalizing treatment strategies based on genomic and clinical data. It discusses how machine learning predicts patient outcomes and optimizes treatment plans while also addressing AI's role in accelerating drug discovery and clinical trials. For an academic audience, this book provides crucial insights into AI's current and future applications in GI oncology. Readers gain a comprehensive understanding of AI diagnostic tools and personalized treatment strategies, equipping researchers and clinicians with the knowledge to leverage these advancements for improved patient care and outcomes in gastrointestinal cancers.

  • The Itch Spectrum

    • 1st Edition
    • Xinzhong Dong + 2 more
    • English
    The Itch Spectrum: The Neurological and Immunological Basis of Itch and Dermatological Disorders covers the latest research on the itch signalling pathway from the skin to the brain. With a multidisciplinary approach, this book will cover the mechanisms underlying the sensation of itch from the fields of neuroscience, immunology, genetics, and dermatology as they have intersected in the study of one somatosensory system. The purpose of this comprehensive reference is to summarize the revelatory discoveries in the field of itch and provide a comprehensive overview of what is known about this remarkable sensation and how various pathologies contribute to chronic pruritis.

  • Emerging Technologies in Yield Optimization and Production of Biomass Feedstock

    • 1st Edition
    • Yogesh K. Ahlawat
    • English
    Emerging Technologies in Yield Optimization and Production of Biomass Feedstock offers a comprehensive evaluation of biomass feedstock, exploring its diverse productions and the challenges of enhancing transformation efficiency in bioenergy species. The book explores the challenges of bioenergy through case studies, covering various stages: cultivation, harvesting, pre-processing, conversion, and utilization. In each stage, the book explains how to maximize efficiency in yield optimization and production of biomass feedstock using innovative solutions to ensure economic benefits and environmental sustainability. It discusses the molecular farming approach, emphasizing the importance of improving transformation efficiency in bioenergy species.The book then reviews species like algae, switchgrass, corn, poplars, and sugarcane, assessing their potential and stressing the need for appropriate species selection to optimize bioenergy transformation processes. Users will also find new methods for gene delivery, transformation, and regeneration, and their applications in modifying bioenergy species for enhanced traits. Additionally, the book covers synthetic biology tools like biosensors, genetic circuits, and pathway engineering, explaining how these tools can be used to further enhance transformation efficiency in bioenergy species.

  • Plant Proteins

    Nutritional Aspects and Processing Applications
    • 1st Edition
    • Nisar Ahmad Mir + 1 more
    • English
    Plant Proteins: Nutritional Aspects and Processing Applications covers various methods used to extract and purify plant proteins for nutrition, health, and new product development. The book identifies techniques and modifications such as fermentation, radiation, and ball-milling to characterize plant protein structure and functionality. Readers will learn how each method serves a different purpose in enhancing flavor, texture, and/or shelf-life. A special focus on plant-based meat is discussed, along with insights on how plant-based proteins effect digestive wellness and the microbiome. Additional sections address the nano-reduction of plant-based proteins and their role in the delivery of different bioactive compounds and health benefits.

  • Algae Classification and Species

    • 1st Edition
    • Pau Loke Show + 3 more
    • English
    Algae Classification and Species delivers a detailed overview of freshwater and marine algal diversity. It provides an essential introduction to the study of phycology with broad applications in diverse biological and biotechnological fields. Written and edited by a global team of experts in the field of phycology, this book is organized according to major algal taxa, including green, red, and brown macroalgae, benthic and planktonic algae, blue-green algae, diatoms, cyanobacteria, and microalgae. Chapters are structured to provide readers with a sweeping understanding of the breadth of marine algae, including their principal characteristics, evolution, phylogeny, distribution, preservation, and more.This book is designed to provide a complete, legible review of algal diversity. It is a valuable resource for researchers, biotechnologists, and students interested in developing their understanding of basic algal biology.

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