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Elsevier

Books in Life sciences

  • Artificial Intelligence and Big Data Analytics for Smart Healthcare

    • 1st Edition
    • Miltiadis Lytras + 3 more
    • English
    Artificial Intelligence and Big Data Analytics for Smart Healthcare serves as a key reference for practitioners and experts involved in healthcare as they strive to enhance the value added of healthcare and develop more sustainable healthcare systems. It brings together insights from emerging sophisticated information and communication technologies such as big data analytics, artificial intelligence, machine learning, data science, medical intelligence, and, by dwelling on their current and prospective applications, highlights managerial and policymaking challenges they may generate. The book is split into five sections: big data infrastructure, framework and design for smart healthcare; signal processing techniques for smart healthcare applications; business analytics (descriptive, diagnostic, predictive and prescriptive) for smart healthcare; emerging tools and techniques for smart healthcare; and challenges (security, privacy, and policy) in big data for smart healthcare. The content is carefully developed to be understandable to different members of healthcare chain to leverage collaborations with researchers and industry.

  • Data Science for COVID-19

    Volume 2: Societal and Medical Perspectives
    • 1st Edition
    • Utku Kose + 3 more
    • English
    Data Science for COVID-19, Volume 2: Societal and Medical Perspectives presents the most current and leading-edge research into the applications of a variety of data science techniques for the detection, mitigation, treatment and elimination of the COVID-19 virus. At this point, Cognitive Data Science is the most powerful tool for researchers to fight COVID-19. Thanks to instant data-analysis and predictive techniques, including Artificial Intelligence, Machine Learning, Deep Learning, Data Mining, and computational modeling for processing large amounts of data, recognizing patterns, modeling new techniques, and improving both research and treatment outcomes is now possible.

  • Analytical Techniques in Biosciences

    From Basics to Applications
    • 1st Edition
    • Chukwuebuka Egbuna + 4 more
    • English
    Analytical Techniques in Biosciences: From Basics to Applications presents comprehensive and up-to-date information on the various analytical techniques obtainable in bioscience research laboratories across the world. This book contains chapters that discuss the basic bioanalytical protocols and sample preparation guidelines. Commonly encountered analytical techniques, their working principles, and applications were presented. Techniques, considered in this book, include centrifugation techniques, electrophoretic techniques, chromatography, titrimetry, spectrometry, and hyphenated techniques. Subsequent chapters emphasize molecular weight determination and electroanalytical techniques, biosensors, and enzyme assay protocols. Other chapters detail microbial techniques, statistical methods, computational modeling, and immunology and immunochemistry.The book draws from experts from key institutions around the globe, who have simplified the chapters in a way that will be useful to early-stage researchers as well as advanced scientists. It is also carefully structured and integrated sequentially to aid flow, consistency, and continuity. This is a must-have reference for graduate students and researchers in the field of biosciences.

  • Cellular and Molecular Aspects of Myeloproliferative Neoplasms - Part A

    • 1st Edition
    • Volume 365
    • English
    Cellular and Molecular Aspects of Myeloproliferative Neoplasms - Part A, Volume 365 in the International Review of Cell and Molecular Biology series reviews and details current advances in cell and molecular biology. Chapters in this new release include MPN a continuum of different disease entities, Bone marrow microenvironment of MPN, Extramedullary hemopoiesis in MPN, The JAK2 mutation, Calreticulin mutations in myeloproliferative neoplasms, and Cytogenetic abnormalities and non-driver mutations in MPN. The IRCMB series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics that are authored by prominent cell and molecular biologists. The articles published in IRCMB have a high impact and an average cited half-life of 9 years. This great resource ranks high amongst scientific journals dealing with cell biology.

  • Innovation Strategies in the Food Industry

    Tools for Implementation
    • 2nd Edition
    • Charis M. Galanakis
    • English
    Innovation Strategies for the Food Industry: Tools for Implementation, Second Edition explores how process technologies and innovations are implemented in the food industry, by i.e., detecting problems and providing answers to questions of modern applications. As in all science sectors, Internet and big data have brought a renaissance of changes in the way academics and researchers communicate and collaborate, and in the way that the food industry develops. The new edition covers emerging skills of food technologists and the integration of food science and technology knowledge into the food chain. This handbook is ideal for all relevant actors in the food sector (professors, researchers, students and professionals) as well as for anyone dealing with food science and technology, new products development and food industry.

  • Psychological and Medical Perspectives on Fertility Care and Sexual Health

    • 1st Edition
    • Kim Bergman + 1 more
    • English
    Psychological and Medical Perspectives on Fertility Care and Sexual Health provides the necessary specialized training of sexual dysfunction and sex therapy to those in reproductive medicine. Understanding and knowledge about these sexual dysfunctions is needed for reproductive specialists to identify sexual problems, provide treatment if they are able or make appropriate referrals, and coordinate care for more specialized and specific needs as part of the patients overall reproductive medical management. This must-have reference explores the intimate interface of sexuality and fertility, male and female sexual function, cultural influences on women, Eastern medicine, and more!

  • Coronavirus Disease

    From Origin to Outbreak
    • 1st Edition
    • Adnan I. Qureshi + 2 more
    • English
    Coronavirus Disease: From Origin to Outbreak provides a comprehensive review of coronaviruses, particularly COVID-19, its transmission, and disease pathology. The book covers the viral structure and genetics of coronaviruses, the pathogenesis and unique characteristics of coronavirus infection, and the evolving nature of our understanding of coronaviruses and disease. It also looks at the history of SARS-CoV and MERS-CoV infections and its global spread. The book examines the effectiveness of various preventive measures and new therapeutic agents that are either currently available or expected to available. Finally, it details the psychological and societal impact the virus and disease has in outbreak regions and what the financial impact an outbreak has on the healthcare system and local economies.

  • Bioinformatics

    Methods and Applications
    • 1st Edition
    • Dev Bukhsh Singh + 1 more
    • English
    Bioinformatics: Methods and Applications provides a thorough and detailed description of principles, methods, and applications of bioinformatics in different areas of life sciences. It presents a compendium of many important topics of current advanced research and basic principles/approache... easily applicable to diverse research settings. The content encompasses topics such as biological databases, sequence analysis, genome assembly, RNA sequence data analysis, drug design, and structural and functional analysis of proteins. In addition, it discusses computational approaches for vaccine design, systems biology and big data analysis, and machine learning in bioinformatics.It is a valuable source for bioinformaticians, computer biologists, and members of biomedical field who needs to learn bioinformatics approaches to apply to their research and lab activities.

  • Spinal Cord Injury Pain

    • 1st Edition
    • Christine N. Sang + 1 more
    • English
    Spinal Cord Injury Pain presents the basis for preclinical and clinical investigations, along with strategies for new approaches in the treatment of central neuropathic pain. Contributors from the private sector and academia provide a comprehensive review of state-of-the-art research in this challenging space. Topics include Epidemiology of Chronic Pain Following SCI, experimental models and mechanisms of chronic pain in SCI, and new targets and technologies. This book serves as a resource for continued translational research that will result in novel approaches and treatments that improve function and quality of life for individuals with CNP/SCI. Despite a better understanding of the complexity of mechanisms of CNP/SCI, improved medical and surgical management of SCI, and the subsequent acceleration of the identification of new targets and the development of novel analgesics, there is still a great unmet clinical need in the area of CNP following SCI. Hence, this book is a welcomed addition to current research and developments.

  • Advances in Parasitology

    • 1st Edition
    • Volume 114
    • David Rollinson + 1 more
    • English
    Advances in Parasitology, Volume 114, the latest release in this ongoing series, includes medical studies of parasites of major influence, along with reviews of more traditional areas, such as zoology, taxonomy and life history. Chapters in this update include Global Health Governance and the World Health Organization during COVID-19: Current and future impact on control of parasitic diseases towards WHO 2030 targets, Combatting Anthelmintic Resistance in Ruminants, New insights into the Cryptosporidium and cryptosporidiosis in human health and beyond, Control And Elimination Of Lymphatic Filariasis In Oceania: Prevalence, Geographical Distribution, Mass Drug Administration, and Surveillance In Samoa, 1998 To 2017.

  • Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume 1: Principles and Practice of Toxicologic Pathology

    • 4th Edition
    • Wanda M. Haschek + 3 more
    • English
    Haschek and Rousseaux's Handbook of Toxicologic Pathology, recognized by many as the most authoritative single source of information in the field of toxicologic pathology, has been extensively updated to continue its comprehensive and timely coverage. The fourth edition has been expanded to four separate volumes due to an explosion of information in this field requiring new and updated chapters. Completely revised with a number of new chapters, Volume 1, "Principles and the Practice of Toxicologic Pathology," covers the practice of toxicologic pathology in three parts: Principles of Toxicologic Pathology, Methods in Toxicologic Pathology, and the Practice of Toxicologic Pathology. Other volumes in this work round out the depth and breadth of coverage.Volume 2 encompasses "Toxicologic Pathology in Safety Assessment" and "Environmental Toxicologic Pathology". These two sections cover the application of toxicologic pathology in developing specific product classes, principles of data interpretation for safety assessment, and toxicologic pathology of major classes of environmental toxicants. Volumes 3 and 4 provide deep and broad treatment of "Target Organ Toxicity", emphasizing the comparative and correlative aspects of normal biology and toxicant-induced dysfunction, principal methods for toxicologic pathology evaluation, and major mechanisms of toxicity. These volumes comprise the most authoritative reference on toxicologic pathology for pathologists, toxicologists, research scientists, and regulators studying and making decisions on drugs, biologics, medical devices, and other chemicals, including agrochemicals and environmental contaminants. Each volume is being published separately.　

  • Medical Pharmacology and Therapeutics

    • 6th Edition
    • Derek G. Waller + 1 more
    • English
    Medical Pharmacology & Therapeutics provides all the information medical and healthcare students need throughout their degree programme and beyond, including for professional qualifications such as the PSA.This all-round textbook covers basic pharmacology through to drug prescribing in clinical contexts, covering the pathogenic mechanisms of disease; drug actions, side effects, and the therapeutic principles of drug use. It takes a helpful systems-based approach that orders information according to body systems and disease areas, rather than by drug class.Now in its sixth edition, the book has been fully updated to include latest scientific understanding of drug action and administration and current best practice in prescribing medications, informed by the latest national guidelines.

  • Infinity Fish

    Economics and the Future of Fish and Fisheries
    • 1st Edition
    • Ussif Rashid Sumaila
    • English
    Infinity Fish: Economics and the Future of Fish and Fisheries is a practical and science-based reference that demonstrates how to value the benefits from restored marine ecosystems to sustain ocean and fishery resources for years to come. It discusses ecological and economical aspects to support the preservation of marine resources by understanding cost-benefits of fishery management systems. The book explains the economic benefits of restoring ecosystems that have been overexploited and how to maintain fisheries in a sustainable level. Infinity Fish: Economics and the Future of Fish and Fisheries is a useful reference to a wide range of audiences. It is for those who wish to make systematic efforts to develop their fisheries sector, scientists and researchers, anyone in fisheries management, marine resource management, economists, fish farmers, policy makers, leaders and regulators, operations researchers, as well as faculty and students.　

  • CRISPR Genome Surgery in Stem Cells and Disease Tissues

    • 1st Edition
    • Stephen H. Tsang
    • English
    CRISPR Genome Surgery in Stem Cells and Disease Tissues focuses uniquely on the clinical applications of CRISPR/Cas9 based technology. Topics include the latest advances in gene editing and its translational applications to various diseases, including retinal degenerative disease, recessively inherited diseases, and dominantly inherited diseases, to name a few. The book's target audience includes researchers, students, clinicians and the general public. This space that is not currently served by any existing resource, so this publication fills a gap in current literature.

  • Fish Nutrition

    • 4th Edition
    • Ronald W. Hardy + 1 more
    • English
    Fish Nutrition, Fourth Edition is an up-to-date, authoritative presentation of all key elements of the nutrition of fish and crustaceans. As aquaculture is rapidly expanding, more than 200 herbivorous and carnivorous species occupy a diverse range of ecological niches, and have therefore evolved to utilize a wide array of food sources. This new edition highlights these differences and covers the complexity and challenges associated with fish nutrition, addressing nutrient requirements to produce high-quality, healthful and sustainable resources, the essential nutrients for fish species, including proteins and amino acids, vitamins, minerals and essential fatty acids, a feed quality assessment, and fish pathology. Led by a team of international experts, this edition provides readers with new information on the use of high-throughput technologies in fish nutrition research, the role of feeds on the community structure of the microbiome, and advances in essential nutrient requirements.

  • Atkinson's Principles of Clinical Pharmacology

    • 4th Edition
    • Shiew-Mei Huang + 3 more
    • English
    **Selected for Doody’s Core Titles® 2024 in Pharmacology**Atkins... Principles of Clinical Pharmacology, Fourth Edition is the essential reference on the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This well-regarded survey continues to focus on the basics of clinical pharmacology for the development, evaluation and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the fourth edition has been thoroughly updated to provide readers with an ideal reference on the wide range of important topics impacting clinical pharmacology.

  • Advances in Virus Research

    • 1st Edition
    • Volume 111
    • Thomas Mettenleiter + 2 more
    • English
    Advances in Virus Research, Volume 111, the latest release in a serial that highlights new advances in the field, presents interesting and timely chapters authored by an international board of subject matter experts.

  • Biomedical Innovations to Combat COVID-19

    • 1st Edition
    • Sergio Rosales-Mendoza + 2 more
    • English
    Biomedical Innovations to Combat COVID-19 provides an updated overview on the development of vaccines, antiviral drugs and nanomaterials, and diagnostic methods for the fight against COVID-19. Perspectives on such technologies are identified, discussed, and enriched with figures for easy understanding and applicability. Furthermore, it contains basic aspects of virology, immunology, and antiviral drugs that are needed to fully appreciate these innovations. This book is split into four sections: introduction, presenting basic virologic and epidemiological aspects of COVID-19; vaccines against COVID-19, discussing their different types and applications used to develop them; diagnostic approaches for SARS-CoV-2, encompassing advanced sensing and microfluidic-based biosensors; and drug development and delivery, where antivirals based on nanomaterials or drugs are presented. It is a valuable source for virologists, biotechnologists, and members of biomedical field interested in learning more about how novel technologies can be applied to fasten the eradication of the COVID-19 and similar pandemics.

  • Success Is What You Leave Behind

    Fostering Leadership and Innovation
    • 1st Edition
    • Cato Laurencin
    • English
    Success Is What You Leave Behind: Fostering Leadership and Innovation reveals the 16 proven practices that Dr. Cato T. Laurencin has used to build his distinguished career as a renowned orthopedic surgeon, biomedical engineer, educator and mentor. Dr. Laurencin shares his own experiences and how one can utilize them in their own career. The book discusses how to be a leader, how to handle challenging moments, how to foster creativity and innovation, how to use skills and successes to help others, and what he has learned from some of the giants in the world of the life sciences and medicine.

  • Comorbilidad en trastornos psicóticos

    Hacia una mejora del diagnóstico y el abordaje
    • 1st Edition
    • André Barciela Veras + 1 more
    • Spanish
    Obra que detalla con gran pericia los datos que respaldan un innovador enfoque para subclasificar la esquizofrenia y otros trastornos psicóticos en base a las comorbilidades de ansiedad y depresión. Proporciona casos prácticos simulados, criterios diagnósticos del DSM-5, modelos de entrevista específicos para cada una de las cinco comorbilidades en pacientes con psicosis y opciones terapéuticas mejoradas. También se analizan las psicosis relacionadas con el consumo de sustancias, las enfermedades médicas y el tratamiento médico, así como otros factores que contribuyen a los trastornos psicóticos. Esta pionera obra de referencia, única en su área, es un recurso clínico, docente, de investigación y de formación, útil para psiquiatras, psicólogos, profesionales de enfermería, trabajadores sociales, neurólogos y cualquiera que esté interesado en la asistencia y el tratamiento de pacientes con trastornos psicóticos. La obra incluye ejemplos de entrevistas con los pacientes y/o purebas de laboratorio para cada diagnóstico. Detalla los síntomas, cuasipsicóticos y los signos secundarios de las comorbilidades, tanto cuando aparecen de forma aislada como asociados a psicosis. Subraya el significado específico de cada diagnóstico y los papeles contribuyentes de los neurotransmisores, la hipofrontalidad, los traumas psicológicos y la genética.

  • The Inequality of COVID-19

    Immediate Health Communication, Governance and Response in Four Indigenous Regions
    • 1st Edition
    • Eric E. Otenyo + 1 more
    • English
    The Inequality of COVID-19: Immediate Health Communication, Governance and Response in Four Indigenous Regions explores the use of information, communication technologies (ICTs) and longer-term guidelines, directives and general policy initiatives. The cases document implications of the failure of various governments to establish robust policies to mitigate the spread of COVID-19 in a sample of advanced and low-income countries. Because the global institutions charged with managing the COVID-19 crisis did not work in harmony, the results have been devastating. The four Indigenous communities selected were the Navajo of the southwest United States, Siddi people in India, Aboriginal and Torres Strait Islander peoples of Australia and the Maasai in East Africa. Although these are all diverse communities, spread across different continents, their base economic oppression and survival from colonial violence is a common denominator in hypothesizing the public health management outcomes. However, the research reveals that national leadership and other incoherent pandemic mitigation policies account for a significant amount of the devastation caused in these communities.

  • Principles of Nucleic Acid Structure

    • 2nd Edition
    • Stephen Neidle + 1 more
    • English
    Principles of Nucleic Acid Structure, Second Edition, provides the most complete and concise summary of underlying principles and approaches to studying nucleic acid structure, including discussions of X-ray crystallography, NMR, molecular modelling and databases. The book's focus is on a survey of structures that are especially important for biomedical research and pharmacological applications. This updated edition includes the latest advances relevant to recognition of DNA and RNA by small molecules and proteins, including sections on RNA folding, ribosome structure and antibiotic interactions, DNA quadruplexes, DNA and RNA protein complexes and short interfering RNA (siRNA).This reference is a must-have for those seeking an authoritative, comprehensive and up-to-date source on all aspects of nucleic acid structure, from basic first principles to details of recent research results.

  • Dancing Protein Clouds: Intrinsically Disordered Proteins in the Norm and Pathology, Part C

    • 1st Edition
    • Volume 183
    • English
    Dancing Protein Clouds: Intrinsically Disordered Proteins in the Norm and Pathology, Part C, Volume 183 represents a set of selected studies on a variety of research topics related to intrinsically disordered proteins. Topics in this volume include discussions on the evolution of disorder, consideration of the peculiarities of phase separation of the prion protein, a general discussion of the relationships between intrinsic disorder and protein functions, coverage of the structural and functional characterization of several important intrinsically disordered proteins, such as transcription factors, outer membrane porins, trans-membrane and membrane associated proteins with ID regions, discussion of molecular simulations of IDPs, and much more.

  • Spider Evolution

    Genetics, Behavior, and Ecological Influences
    • 1st Edition
    • Subir Ranjan Kundu
    • English
    Spider Evolution: Genetics, Behavior, and Ecological Influences provides a thorough exploration of the evolutionary trail of arachnids, particularly spider species, from prehistoric origins to current sustainability issues. This book analyzes extinct organisms in the Arachnida class, specifically looking at their phylogenomics and molecular footprints to understand evolutionary changes in diversification in today’s species. Sections cover spider origins and their influences on behavioral traits, physiology of sensory organs, and biomechanics, also touching on spiders as prey and predators and how their roles have changed in the 400 million years of Arachnida existence. The book then focuses upon current environmental issues facing spider species and how these have, and can, affect the evolution of these organisms. Topics include biodiversity minimization, climate change and natural disasters. This book is a much-needed resource for entomologists and arachnid- or arthropod-driven researchers. Advanced undergraduate and graduate students will also benefit from the historic review, current assessment and future predictions of spider evolution provided in this book.

  • Advances in Immunology

    • 1st Edition
    • Volume 151
    • Frederick W. Alt
    • English
    Advances in Immunology, Volume 151, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology.

  • Vascular Surgery

    A Clinical Guide to Decision-making
    • 1st Edition
    • Piergiorgio Settembrini + 1 more
    • English
    Vascular Surgery: A Clinical Guide to Decision-making is a concise but comprehensive resource for operating vascular surgeons and clinicians. It serves as an essential reference manual, particularly to young vascular surgeons, for consulting the basic scientific knowledge of pathogenesis of various illnesses, as well as how to approach them in a clinical setting. Adopting a translational approach, this book dissects the background of vascular pathology and links it to application in surgical techniques, as well as providing practical tips and tricks for surgical maneuvers. With insights and suggestions from various experienced and skilled vascular surgeons, this book covers a range of topics including the origin of diseases, clinical presentation, and therapeutic options, from medical therapy to surgical or endovascular approach. Each chapter also reviews international cutting-edge research in the vascular field and its clinical application, illuminating future developments in the field. With the contributions of first-class vascular surgeons, this book also covers uncommon and advanced case studies while exploring the pros and cons of each intervention option, helping practitioners make informed decisions when facing difficult cases. This unique reference also helps young surgeons to make quick decisions in challenging cases, such as how to choose between open and endo treatment.

  • Pediatric Headache

    • 1st Edition
    • Jack Gladstein + 2 more
    • English
    Covering the topic of headache in children from the viewpoint of both primary care and neurology, Pediatric Headache provides concise, authoritative guidance on all aspects of this multifaceted subject. Drs. Jack Gladstein, Christina Szperka, and Amy Gelfand, each an expert in pediatric headache, contribute their considerable knowledge and expertise to assist neurologists, pediatricians, and primary care providers in providing optimal care to young patients.

  • Proteolytic Signaling in Health and Disease

    • 1st Edition
    • Andre Zelanis
    • English
    In recent years, powered by evolving technologies and experimental design, studies have better illuminated the regulating role of proteolytic enzymes across human development and pathologies. Proteolytic Signaling in Health and Disease provides an in-depth discussion of fundamental physiological and developmental processes regulated by proteases, from protein turnover and autophagy to antigen processing and presentation and major histocompatibility complex (MHC) molecules. Moving on from basic biology, international chapter authors examine a range of pathological conditions associated with proteolysis, including inflammation, wound healing, and cancer. Later chapters discuss the newly discovered network of connected events among proteases (and their inhibitors), the so-called ‘protease web’, and how best to study it. This book also empowers new research with up-to-date analytical methods and step-by-step protocols for studying proteolytic signaling events.

  • History of Modern Clinical Toxicology

    • 1st Edition
    • Alan Woolf
    • English
    History of Modern Clinical Toxicology describes the extraordinary advances in the practice of clinical toxicology within the past 70 years and brings together stories of the people – the champions of clinical toxicology - who contributed to these advances, discovered new therapies and antidotes, and made change happen. This book lays out the poison control system they built and the fascinating story of how they created a new and evolving medical specialty. With the participation of renowned international experts as authors, the book showcases the development of poison control centers around the world and the growth of the professional societies that represent and support them today. This book also tells the stories of the modern-day toxic disasters and recent toxic exposures that gained worldwide attention and notoriety. It outlines the public health responses to such calamities which have led to improvements in our understanding of the science and changes in public health policies and regulations to forestall future such events. Finally, the book covers key policies and agencies affecting poison control centers, addresses the challenges facing clinical toxicologists of today, and predicts advances and future innovations in the field. History of Modern Clinical Toxicology is a unique resource that provides the historical and international perspective that will help students, practitioners, scientists, and health policy makers put current issues and methods in perspective. It will help them understand how infrastructure and processes in clinical toxicology have evolved and why poison control systems are configured as they are.

  • Storage Systems

    Organization, Performance, Coding, Reliability, and Their Data Processing
    • 1st Edition
    • Alexander Thomasian
    • English
    Storage Systems: Organization, Performance, Coding, Reliability and Their Data Processing was motivated by the 1988 Redundant Array of Inexpensive/Independ... Disks proposal to replace large form factor mainframe disks with an array of commodity disks. Disk loads are balanced by striping data into strips—with one strip per disk— and storage reliability is enhanced via replication or erasure coding, which at best dedicates k strips per stripe to tolerate k disk failures. Flash memories have resulted in a paradigm shift with Solid State Drives (SSDs) replacing Hard Disk Drives (HDDs) for high performance applications. RAID and Flash have resulted in the emergence of new storage companies, namely EMC, NetApp, SanDisk, and Purestorage, and a multibillion-dollar storage market. Key new conferences and publications are reviewed in this book.The goal of the book is to expose students, researchers, and IT professionals to the more important developments in storage systems, while covering the evolution of storage technologies, traditional and novel databases, and novel sources of data. We describe several prototypes: FAWN at CMU, RAMCloud at Stanford, and Lightstore at MIT; Oracle's Exadata, AWS' Aurora, Alibaba's PolarDB, Fungible Data Center; and author's paper designs for cloud storage, namely heterogeneous disk arrays and hierarchical RAID.

  • The NET-Heart Book

    Neglected Tropical Diseases and other Infectious Diseases affecting the Heart
    • 1st Edition
    • Clara Saldarriaga + 1 more
    • English
    Neglected Tropical Diseases and other Infectious Diseases Affecting the Heart provides a comprehensive and systematic review on the literature surrounding Neglected Tropical Diseases and infectious diseases and how they affect the heart. Written by Emerging Leaders of the Interamerican Society of Cardiology (SIAC), the book includes the latest research findings, covering the cardiac involvement of a range of viral, bacterial and parasitic diseases, including COVID19, HIV, Zika, Lyme Disease, and more. Chapters cover epidemiology, the physiopathology of cardiovascular involvement, symptoms, diagnosis, and treatment options for each disease, making the book suitable to researchers, scientists, clinicians and physicians in the field.

  • Coeliac Disease and Gluten-Related Disorders

    • 1st Edition
    • Annalisa Schiepatti + 1 more
    • English
    Coeliac Disease and Gluten-Related Disorders provides an updated and comprehensive overview on the crucial aspects and clinical management of gluten-related disorders. It provides an overview of the scientific background, mechanisms involved, and emphasizes the translational effect of research on clinical practice. Highlighted throughout are insights into future research areas likely to have a crucial impact in the clinical management of these common conditions. The book is perfect for researchers and gastroenterologists involved in Coeliac Disease and other gluten-related disorders.

  • Advances in Arthropod Repellents

    • 1st Edition
    • Joel Coats + 2 more
    • English
    Advances in Arthropod Repellents offers the most current knowledge on arthropod repellents. This area of study is quickly evolving as mosquito- and tick-borne diseases become more prevalent worldwide. Written by global arthropod repellent experts, this book begins by delving into molecule discovery and assay development that is followed by the latest research and investigations of repellent developments and effects. The book then offers readers a look into the global field, semi-field, and laboratory trials using various insect repellents, ranging from Africa, Australia, Europe, South America and the United States. Lastly, it examines the future of spatial repellents and expert insight. This book is a valuable resource for entomologists and vector control researchers and practitioners. Public health officials and developers in private pest control companies, as well as readers in academia will find this a useful resource to learn the latest information available on controlling the spread of arthropod-borne diseases with repellents.

  • Student Workbook for Pharmacology Made Simple

    • 1st Edition
    • Anthony Guerra
    • English
    Reinforce your understanding of pharmacology with this practical workbook! Corresponding to the chapters in Pharmacology Made Simple, this workbook helps you review, practice, and apply the pharmacology knowledge you will need as a healthcare professional. Review questions and exercises provide "skills drills"-style practice to help you understand and apply key terms and concepts. Not only will you get more out of the textbook, but you will also gain confidence and improve your job readiness!

  • Biophotonics, Tryptophan and Disease

    • 1st Edition
    • Laura A. Sordillo + 1 more
    • English
    Biophotonics, Tryptophan and Disease is a comprehensive resource on the key role of tryptophan in wide range of diseases as seen by using optics techniques. It explores the use of fluorescence spectroscopy, Raman, imaging techniques and time-resolved spectroscopy in normal and diseased tissues and shows the reader how light techniques (i.e. spectroscopy and imaging) can be used to detect, distinguish and evaluate diseases. Diseases covered include cancer, neurodegenerative diseases and other age-related diseases. Biophotonics, Tryptophan and Disease offers a clear presentation of techniques and integrates material from different disciplines into one resource. It is a valuable reference for students and interdisciplinary researchers working on the interface between biochemistry and molecular biology, translational medicine, and biophotonics.

  • Methodological Approaches for Sleep and Vigilance Research

    • 1st Edition
    • Eric Murillo-Rodriguez
    • English
    Methodological Approaches for Sleep and Vigilance Research examines experimental procedures used to study the sleep-wake cycle, with topics covered by world leaders in the field. The book focuses on techniques commonly used in the sleep field, including polysomnography, electrophysiology, single- and multi-unit spiking activity recording, brain stimulation, EEG power spectra, optogenetics, telemetry, and wearable and non-wearable tracking devices. Further chapters on imaging techniques, questionnaires for sleep assessment, genome-wide association studies, artificial intelligence and big data are also featured. This discussion of significant conceptual advances into experimental procedures is suitable for anyone interested in the neurobiology of sleep.

  • Nutritional Management of Renal Disease

    • 4th Edition
    • Joel D. Kopple + 2 more
    • English
    Nutritional Management of Renal Disease, Fourth Edition, offers in-depth reviews of the metabolic and nutritional disorders prevalent in patients with renal disease and serves as an in-depth reference source concerning nutrition and kidney disease. This classic translational reference provides correct diagnosis - and therefore correct treatment - of renal, metabolic, and nutritional disorders. Nephrologists, diebetologists, endocrinologists, dieticians, and nutritionists depend on a strong understanding of the molecular basis for the disease. This fourth edition includes thorough new case reports, offering expert advice on how to use the latest research and clinical findings in counseling patients about dietary and lifestyle options. Readers gain insight into which treatments, medications, and diets to use based on the history, progression, and genetic make-up of a patient.

  • Paclitaxel

    Sources, Chemistry, Anticancer Actions, and Current Biotechnology
    • 1st Edition
    • Mallappa Kumara Swamy + 2 more
    • English
    Paclitaxel: Sources, Chemistry, Anticancer Actions, and Current Biotechnology provides a comprehensive survey of Paclitaxel and its derivatives chemistry, biosynthesis and anticancer activities. In addition, biotechnological methods, including cell cultures, the use of bioreactors and metabolic engineering strategies to improve Paclitaxel production are also discussed. The book discusses topics such as mechanisms of action against cancer, novel forms of Paclitaxel for an effective cancer treatment, strategies for enhancing its bioavailability, and the application of nanocarriers for its delivery and chemotherapy of cancer. This is a valuable resource for cancer researchers, biotechnologists and members of biomedical field who are interested in the promising anticancer qualities of this antineoplastic drug and how to enhance them for better treatments.

  • Blood Gases and Critical Care Testing

    Physiology, Clinical Interpretations, and Laboratory Applications
    • 3rd Edition
    • John G. Toffaletti + 1 more
    • English
    Blood gas tests are a group of tests that are widely used and essential for the evaluation and management of a patient’s ventilation, oxygenation, and acid-base balance, often in emergent situations, and along with blood gases are other critical care analytes measured on blood: calcium, magnesium, phosphate, and lactate. Blood Gases and Critical Care Testing: Clinical Interpretations and Laboratory Applications, Third Edition, serves as your single most important reference for understanding blood gases and critical care testing and interpretation. The third edition of this classic book is a complete revision and provides the fundamentals of blood gas (pH, pCO2, pO2) and other critical care tests (calcium, magnesium, phosphate, and lactate), including the history, the definitions, the physiology, and practical information on sample handling, quality control and reference intervals. Case examples with clear clinical interpretations of critical care tests have been included to all chapters. This book will serve as a valuable and convenient resource for clinical laboratory scientists in understanding the physiology and clinical use of these critical care tests and for providing practical guidelines for successful routine testing and quality monitoring of these tests.

  • Electromyography, An Issue of Neurologic Clinics

    • 1st Edition
    • Volume 39-4
    • Devon I. Rubin
    • English
    This issue of Neurologic Clinics, guest edited by Dr. Devon I. Rubin, will cover key topics in Electromyography. This issue is one of four selected each year by our series consulting editor, Dr. Randolph W. Evans. Topics discussed in this issue will include: Nerve Conduction Studies, Needle EMG, Electrodiagnostic Assessment of Uncommon Mononeuropathies, EDX Assessment of Uncommon Mononeuropathies, Electrodiagnostic Assessment of Radiculopathies, Electrodiagnostic Assessment of Plexopathies, Electrodiagnostic Assessment of Polyneuropathy, Electrodiagnostic Assessment of Myopathy, Electrodiagnostic Assessment of Neuromuscular Junction Disorders, Electrodiagnostic Assessment of Motor Neuron Diseases, Electrodiagnostic Assessment of Hyperexcitable Nerve Disorders, and EMG Case Examples.　

  • Herbal Biomolecules in Healthcare Applications

    • 1st Edition
    • Subhash C. Mandal + 2 more
    • English
    Herbal Biomolecules in Healthcare Applications presents extensive detailed information on all the vital principles, basics and fundamental aspects of multiple herbal biomolecules in the healthcare industry. This book examines important herbal biomolecules including alkaloids, glycosides, flavonoids, anthraquinones, steroids, polysaccharides, tannins and polyphenolic compounds, terpenes, fats and waxes, proteins and peptides, and vitamins. These herbal biomacromolecules are responsible for different bioactivities as well as pharmacological potentials. A systematic understanding of the extraction, purification, characterization, applications of these herbal biomolecules and their derivatives in healthcare fields is developed in this comprehensive book. Chapters explore the key topics along with an emphasis on recent research and developments in healthcare fields by leading experts. They include updated literature review of the relevant key topics, good quality illustrations, chemical structures, flow charts, well-organized tables and case studies. Herbal Biomolecules in Healthcare Applications will be useful for researchers working on natural products and biomolecules with bioactivity and nutraceutical properties. Professionals specializing in scientific areas such as biochemistry, pharmacology, analytical chemistry, organic chemistry, clinics, or engineering focused on bioactive natural products will find this book useful.

  • Phytoremediation

    Biotechnological Strategies for Promoting Invigorating Environs
    • 1st Edition
    • Rouf Ahmad Bhat + 3 more
    • English
    Phytoremediation: Biotechnological Strategies for Promoting Invigorating Environs focuses on phytoremediation’s history, present and future potential, discussing mechanisms of remediation, different types of pollutant and polluted environs, cell signaling, biotechnology, and molecular biology, including site-directed DNA and the omics related to plant sciences. Sections focus on phytoremediation as an economically feasible and environmentally safe strategy, including its mechanisms from macroscopic to microscopic level, strategies of assisted phytoremediation, the role of omics on innovations on the field, the development of genetically modified plants (GMPs) to deal with pollutants, the future prospects of targeted genetic engineering in phytoremediation and remediation advantages and disadvantages. Other sections in the book explore the phytoremediation of specific environs (water and soil) and specific contaminants that are of major worldwide concern.

  • Plant Perspectives to Global Climate Changes

    Developing Climate-Resilient Plants
    • 1st Edition
    • Tariq Aftab + 1 more
    • English
    Plant Perspectives to Global Climate Changes: Developing Climate-Resilient Plants reviews and integrates currently available information on the impact of the environment on functional and adaptive features of plants from the molecular, biochemical and physiological perspectives to the whole plant level. The book also provides a direction towards implementation of programs and practices that will enable sustainable production of crops resilient to climatic alterations. This book will be beneficial to academics and researchers working on stress physiology, stress proteins, genomics, proteomics, genetic engineering, and other fields of plant physiology. Advancing ecophysiological understanding and approaches to enhance plant responses to new environmental conditions is critical to developing meaningful high-throughput phenotyping tools and maintaining humankind’s supply of goods and services as global climate change intensifies.

  • Cyanobacterial Lifestyle and its Applications in Biotechnology

    • 1st Edition
    • Prashant Kumar Singh + 2 more
    • English
    Environmental change is affecting the world's agricultural productivity. This is coupled with an increase in population: according to the United Nations Department for Economic and Social Affairs, the global population is estimated to reach 9.7 billion by 2050. Therefore, the current situation requires that we develop climate-smart technologies to improve crop productivity to sustain the ever-rising global population. Current-day farmers are introducing a considerable amount of agrochemicals to enhance crop productivity. Indiscriminate agrochemical application has altered not only the soil's physic-chemical and biological properties but also affected human health through food chain contamination. Cyanobacteria, under these changing environmental conditions, may help to resolve the problem significantly without changing the natural soil properties. In spite of their well-known stress tolerance potential, most of the cyanobacterial stress management and signaling pathways are yet to be fully characterized. Therefore, there is an urgent need to explore cyanobacterial metabolism under stress as well as their regulatory pathways to exploit them for sustainable agriculture. In recent decades, the application of cyanobacteria has attracted scientists because of uniqueness, better adaptability, and synthetic products. Diverse cyanobacterial communities with the ability to fix atmospheric nitrogen, together with their photosynthetic properties, have demonstrated their application under field conditions. Several cyanobacterial species have thus been exploited to enhance soil fertility, mitigate biotic and abiotic stress, and contamination management. Cyanobacterial Lifestyle and its Applications in Biotechnology has been designed to discuss different aspects of cyanobacterial physiology with the aim of helping to provide a better understanding of advanced cyanobacterial molecular biology and their metabolism to uncover the potential of cyanobacteria in the tailoring of stress smart crops for sustainable agriculture. Chapters include valuable information about the role of cyanobacteria in the evolution of life, cyanobacterial photosynthesis, stress-tolerant cyanobacterium, biological nitrogen fixation, circadian rhythms, genetics and molecular biology of abiotic stress responses.

  • Current research on naturally transmitted Plasmodium knowlesi

    • 1st Edition
    • Volume 113
    • Russell Stothard + 1 more
    • English
    Plasmodium Knowlesi, Volume 113 in the Advances in Parasitology series, includes medical studies of parasites of major influence, along with reviews of more traditional areas, such as zoology, taxonomy and life history. Chapters in this update include Taking the strain out of onchocerciasis: a reanalysis of blindness and transmission data does not support the existence of a savanna blinding strain of onchocerciasis in West Africa, Enterocytozoon bieneusi of animals, Taenia solium taeniasis/cysticerco... Genomic analysis reveals predominant clonality and progressive evolution at all evolutionary scales in eukaryotic pathogens, HTLV-I and Strongyloides: the worm lurking beneath, and more.

  • Wound Healing, Fibrosis, and the Myofibroblast

    A Historical and Biological Perspective
    • 1st Edition
    • Giulio Gabbiani + 2 more
    • English
    Wound Healing, and the Myofibroblast: A Historical and Biological Perspective is the fruit of an interdisciplinary and international collaboration involving a historian of medicine (Dr. Zampieri), a physician (Dr. Coen), and a researcher (Prof. Gabbiani, world-renowned for his discovery of the myofibroblast). This book aims to draw a concise yet complete description of the conceptual evolution of wound healing, fibrosis and fibrosis-related pathologies from antiquity to present time, as well as commenting on the role of the myofibroblast and the key cell type essential for tissue repair and fibrosis (from its identification in 1971 throughout its 50-years-old history).By viewing this complex and century-long history from different perspectives, the book's authors aim to draw an exhaustive overview, with the hope of inspiring new and fruitful basic and clinical research.

  • Advances in Marine Biology

    • 1st Edition
    • Volume 89
    • Jean-Francois Hamel
    • English
    Advances in Marine Biology, Volume 89 updates on many topics that will appeal to postgraduates and researchers in marine biology, fisheries science, ecology, zoology and biological oceanography. Chapters in this new release include Bio-concretions of submarine caves and/or on resting stages from plankton and the Resurrection Ecology, Shallow subtidal rocky reefs of the Mediterranean, From an economic crisis to a pandemic crisis: The need for accurate marine monitoring data to take informed management decisions, Backcasting vs. forecasting, about the paradox of Jevons, sustainability, the ecological transition, and the translation of scientific knowledge into policy, Shark biology and conservation, and more.

  • Emerging Concepts in Ribosome Structure, Biogenesis, and Function

    • 1st Edition
    • Vijay Kumar
    • English
    Ribosome biogenesis is the process of making ribosomes which are responsible for mRNA translation into proteins. It is a tightly regulated process closely linked to nearly all biochemical and cellular processes, including cell division, growth, and development. Emerging Concepts in Ribosome Structure, Biogenesis, and Function provides a synthesized overview of all the parts engaged in this process. The book begins by providing an introduction to the ribosome factory, its origin, and its evolution of translation. It then goes on to describe ribosome structure including subunits, RNA, and protein components. Ribosome biogenesis and its emergence as a frontier research area for translational potential in cancer and other diseases are also discussed. In addition, the book explores current developments in ribosome research like the emergence of ribosomopathies, how deregulation of ribosome biogenesis can impact disease mechanisms and aging, and the discovery of specialized ribosomes that have specific functions that may translate differentially with consequences on normal and pathological processes. Emerging Concepts in Ribosome Structure, Biogenesis, and Function provides fundamental coverage and emerging research on ribosomes, biogenesis, and their structure and function and is a resourceful introduction for new researchers and those engaged in interdisciplinary ribosomal research.

  • Sustainable Fish Production and Processing

    • 1st Edition
    • Charis M. Galanakis
    • English
    Sustainable Fish Production and Processing is a unique resource that bridges the gap between academia and industry by analyzing new, state-of-the-art fish production, processing and waste management. The book explores general valorization methods, focusing on the extraction of high added-value compounds and their reutilization in different fields of the food and nutraceuticals industry. Sections take a comprehensive approach to understanding the most recent advances in the field, while also analyzing the potentiality and sustainability of already commercialized processes and products. This resource could be utilized as a handbook for anyone dealing with sustainability issues within the fish industry.Emphasis of fish production is given to food security issues, large marine ecosystems, aquaculture genomics, epigenetics and breeding, proteomics for quality and safety in fishery products, post-harvest practices in small scale fisheries, and lifecycle impact of industrial aquaculture systems. Emphasis of fish processing and by-products is given to industrial thawing of fish blocks, sources and functional properties of fish protein hydrolysates, recovery technologies and applications, potential biomedical applications, ready-to-eat products, fish waste for bacterial protease production, fish waste for feeding as well as lipid extraction from fish processing for biofuels.

  • Clinical Pharmacology During Pregnancy

    • 2nd Edition
    • Donald Mattison + 1 more
    • English
    Clinical Pharmacology During Pregnancy, Second Edition is written for clinicians, physicians, midwives, nurses, pharmacists and other medical professionals involved in the care of women during pregnancy. The book focuses on the impact of pregnancy on drug disposition and includes coverage of treatments for diseases of specific body systems as well as essential content on dosing and efficacy. This update includes substantially expanded sections on the ethics of pharmacological research in pregnancy and physiologic changes, along with new sections on patient reported outcomes in pregnancy, delivery and postnatal care, and the use of pharmacokinetic and pharmacodynamic approaches to estimate maternal, placental and fetal dosing. The broad range of this book encompasses analgesics, antiasthmatics, antidepressants, heart and circulatory drugs, vitamins and herbal supplements, and more. Topics in chemotherapy and substance abuse are also covered, as are research issues, including clinical trial design and ethical considerations.

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