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Books in Life sciences

    • Advances in Immunology

      • 1st Edition
      • Volume 135
      • August 18, 2017
      • English
      • Hardback
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      • eBook
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      Advances in Immunology, Volume 135, the latest in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, with this latest update including chapters on GPCR Biology, the Role of Caveolin-1 in BCR and TCR Receptors, New Developments in the Chemokine Field, and The Complement System in Developmental Neurobiology and Neurodegeneration. Readers will find comprehensive information on molecular and cellular activation mechanisms, phylogeny and molecular evolution and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future.
    • Hydronephrosis

      • 1st Edition
      • May 17, 2017
      • James C. Anderson
      • English
      • Paperback
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      • Hardback
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      • eBook
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      Hydronephrosis is a seven chapter text that brings together the technical and scientific advances that have improved the treatment of hydronephrosis. Hydronephrosis is the dilatation of the renal pelvis and calyces due to functional or mechanical disorder of the upper end of the ureter or the pelvis of the kidney. The introductory chapter provides an overview of the historical developments in the diagnosis and treatment options of hydronephrosis. The succeeding chapters discuss the disease's clinical manifestations, structural and functional aspects, symptoms, diagnosis, and operative procedures. The concluding chapters present various case histories on the results of surgical treatments of hydronephrotic patients. This book will be of value to urologists and kidney surgeons.
    • Biomarkers in Inborn Errors of Metabolism

      • 1st Edition
      • June 1, 2017
      • Uttam Garg + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 8 0 2 8 9 6 4
      • eBook
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      Biomarkers of Inborn Errors in Metabolism: Clinical Aspects and Laboratory Determination is structured around the new reality that laboratory testing and biomarkers are an integral part in the diagnosis and treatment of inherited metabolic diseases. The book covers currently used biomarkers as well as markers that are in development. Because biomarkers used in the initial diagnosis of disease may be different than the follow-up markers, the book also covers biomarkers used in both the prognosis and treatment of inherited metabolic disorders. With the introduction of expanded new-born screening for inborn metabolic diseases, an increasing numbers of laboratories are involved in follow-up confirmatory testing. The book provides guidance on laboratory test selection and interpreting results in patients with suspected inherited metabolic diseases. The book provides comprehensive guidance on patient diagnosis and follow-up through its illustrative material on metabolic pathways, genetics and pathogenesis, treatment and prognosis of inherited metabolic diseases, along with essential information on clinical presentation. Each chapter is organized with a uniform, easy-to-follow format: a brief description of the disorder and pathway; a description of treatment; biomarkers for diagnosis; biomarkers followed for treatment efficacy; biomarkers followed for disease progression; confounding conditions that can either: affect biomarker expression or mimic IEMs; other biomarkers: less established, future.
    • In Vitro Toxicology

      • 1st Edition
      • November 13, 2017
      • Alok Dhawan + 1 more
      • English
      • Paperback
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      • eBook
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      In Vitro Toxicology details the protocols and methods of in vitro testing, highlighting the usefulness of models, methods and the cost-effectiveness and reproducibility of such methodologies. The current approaches and strategies required to develop an easy, reliable, validated and high throughput system for use in alternative animal models to circumvent in vivo testing are discussed in detail. The book also includes chapters on the principles involved in the general selection and use of models that address safety concerns, regulatory acceptance and the current understandings and strategies for the identification of biomarkers in toxicity testing. Furthermore, principles involved in the general selection and use of models that address the issues of safety concerns and regulatory acceptance of these models are discussed, making the book beneficial to students, scientists, and regulators working in toxicology, as well as those in the field of chemicals and the safety assessment of novel materials.
    • Molecular and Cellular Therapies for Motor Neuron Diseases

      • 1st Edition
      • January 16, 2017
      • Nicholas M Boulis + 2 more
      • English
      • Hardback
        9 7 8 0 1 2 8 0 2 2 5 7 3
      • eBook
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      Molecular and Cellular Therapies for Motor Neuron Diseases discusses the basics of the diseases, also covering advances in research and clinical trials. The book provides a resource for students that will help them learn the basics in a detailed manner that is required for scientists and clinicians. Users will find a comprehensive overview of the background of Amyotrophic Lateral Sclerosis (ALS/Lou Gehrig’s Disease) and Spinal Muscular Atrophy (SMA), along with the current understanding of their genetics and mechanisms. In addition, the book details gene and cell therapies that have been developed and their translation to clinical trials.
    • Algal Green Chemistry

      • 1st Edition
      • April 14, 2017
      • Rajesh Prasad Rastogi + 2 more
      • English
      • Hardback
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      • eBook
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      Algal Green Chemistry: Recent Progress in Biotechnology presents emerging information on green algal technology for the production of diverse chemicals, metabolites, and other products of commercial value. This book describes and emphasizes the emerging information on green algal technology, with a special emphasis on the production of diverse chemicals, metabolites, and products from algae and cyanobacteria. Topics featured in the book are exceedingly valuable for researchers and scientists in the field of algal green chemistry, with many not covered in current academic studies. It is a unique source of information for scientists, researchers, and biotechnologists who are looking for the development of new technologies in bioremediation, eco-friendly and alternative biofuels, biofertilizers, biogenic biocides, bioplastics, cosmeceuticals, sunscreens, antibiotics, anti-aging, and an array of other biotechnologically important chemicals for human life and their contiguous environment. This book is a great asset for students, researchers, and biotechnologists.
    • The Role of Neuropeptides in Addiction and Disorders of Excessive Consumption

      • 1st Edition
      • Volume 136
      • October 24, 2017
      • English
      • Hardback
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      • eBook
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      The Role of Neuropeptides in Addiction and Disorders of Excessive Consumption, Volume 136 in the International Review of Neurobiology series, provides an overview of the top candidate neuropeptides in the modulation of alcohol and drug abuse, also covering eating disorders and obesity. Topics covered in this latest release include Corticotropin Releasing Factor (CRF) and Addictive Behaviors, Dynorphin/Kappa Opioid Receptor Signaling in Pre-clinical Models of Alcohol, Drug, and Food Addiction, The Role of Ghrelin Signaling in Additive Behaviors, The Role of the Melanocortin System in Drug and Eating Disorders, Substance P and the Neurokinin-1 Receptor: The New CRH, and the Role of Neuropeptide Y (NPY) in Drug and Eating Disorders. The book uniquely highlights the overlapping central mechanisms that contribute to both drug and alcohol abuse and eating disorders.
    • Control of Growth and Metamorphosis

      • 1st Edition
      • May 3, 2017
      • Penelope M. Jenkin
      • G. A. Kerkut
      • English
      • Paperback
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      • eBook
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      International Series of Monographs in Pure and Applied Biology: Zoology Division, Volume 47: Control of Growth and Metamorphosis details the differences in animal hormones. The title focuses on covering morphogenetic hormones. The selection first defines and classifies morphogenetic hormones, and then proceeds to detailing the sources of hormones related to morphogenesis. Next, the selection tackles growth and mitosis, along with molting and metamorphosis. The last chapter deals with the control of morphogenetic hormones. The book will be of great use to students, researchers, and practitioners of zoology.
    • The Lateralized Brain

      • 1st Edition
      • November 16, 2017
      • Sebastian Ocklenburg + 1 more
      • English
      • Hardback
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      • eBook
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      The Lateralized Brain: The Neuroscience and Evolution of Hemispheric Asymmetries is an up-to-date teaching resource for neuroscience faculty members that teach courses concerning hemispheric asymmetries. The book provides students with all relevant information on the subject, while also giving aspiring researchers in the field an up-to-date overview of relevant, previous work. It is ideal for courses on hemispheric asymmetries, that is, the functional or structural differences between the left and the right hemispheres of the brain, and also highlights how the widespread use of modern neuroimaging techniques, such as fMRI and DTI has completely changed the way hemispheric asymmetries are currently investigated. According to the preface, the main aim of The Lateralized Brain is to provide "an up-to-date teaching resource on hemispheric asymmetries … [and] to introduce undergraduate students of all levels to the fascinating topics of hemispheric asymmetries" (p. xv)… (Sebastian Ocklenburg and Onur Güntürkün) have succeeded admirably in their stated aim and are to be congratulated on undertaking the mammoth task they set themselves. They can be proud of what they have accomplished.~ Alan A. Beaton, Department of Psychology, Swansea University, Swansea, UK, in Laterality: Asymmetries of Body, Brain and Cognition, July, 2018.
    • Arteriovenous and Cavernous Malformations

      • 1st Edition
      • Volume 143
      • May 25, 2017
      • English
      • Hardback
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      • eBook
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      Arteriovenous and Cavernous Malformations, Volume 143, is the latest addition in the ongoing HCN series, an evidence-based compendium which addresses both the scientific and clinical aspects of this unique disease process. The volume covers didactic aspects, such as the epidemiology, etiology, and diagnosis of AVMs, while also providing expert clinical information on the management and treatment of these lesions. In addition, it provides coverage of modern-day advances in the genetics of cavernous malformations, as well as discussion regarding future open research questions. Readers from the laboratory bench to the bedside can expect a broad, yet objective, review of this pathology, with updates from the latest scientific literature and data supporting current practices.