Life sciences print books and ebooks | Elsevier

The Heart in Systemic Autoimmune Diseases

2nd Edition
Volume 14
February 11, 2017
Fabiola Atzeni + 3 more
English
Hardback
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eBook
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The Heart in Systemic Autoimmune Diseases, Second Edition, provides an overview on our current understanding of major complications relating to the heart and autoimmune diseases. It includes the latest information on the new pathogenetic mechanisms involved, along with clinical manifestations of these important comortbidities. Mortality in autoimmune diseases, in particular, rheumatoid arthritis and SLE, has increased when compared with the general population. This excess mortality is largely due to cardiovascular diseases (CVDs)-particularly those of atherosclerotic origin, such as ischemic heart disease-and is gaining recognition in all branches of medicine, from cardiology, to internal medicine, and from rheumatologists to orthopedics.

Innovative Neuromodulation

1st Edition
January 16, 2017
Jeffrey Arle + 1 more
English
Hardback
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eBook
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Innovative Neuromodulation serves as an extensive reference that includes a basic introduction to the relevant aspects of clinical neuromodulation that is followed by an in-depth discussion of the innovative surgical and therapeutic applications that currently exist or are in development. This information is critical for neurosurgeons, neurophysiologists, bioengineers, and other proceduralists, providing a clear presentation of the frontiers of this exciting and medically important area of physiology. As neuromodulation remains an exciting and rapidly advancing field—appealing to many disciplines—the editors’ initial work (Essential Neuromodulation, 2011) is well complemented by this companion volume.

Cerebrospinal Fluid in Neurologic Disorders

1st Edition
Volume 146
November 17, 2017
English
Hardback
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eBook
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Cerebrospinal Fluid in Neurologic Disorders, Volume 146 provides a brief overview on the current use of CSF in clinical routine, the physiology of CSF, and its usefulness and potential as a biomarker. The second part addresses the main purpose of the volume, describing CSF from a research perspective in context with the most important diagnostic entities in neurology. The book's authors provide insight into the current understanding of CSF changes in these various conditions and what it tells us about the nature of neurological diseases. Furthermore, methodological aspects are discussed, as are shortcomings that need to be addressed. Finally, the book provides an outlook for potential directions that can be explored to improve the various aspects of CSF research with the ultimate goal of being incorporated in clinical practice.

Advances in Clinical Chemistry

1st Edition
Volume 81
June 16, 2017
English
Hardback
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eBook
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Advances in Clinical Chemistry, Volume 81, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. New to this latest release are chapters that cover Microparticles in Chronic Heart Failure, Peptide Antibodies in Clinical Laboratory Diagnostics, Measurement and Clinical Utility of βCTX in Serum and Plasma, Human Papillomavirus and its Testing Assays, Cervical Cancer Screening, and Vaccination, and Physical Exercise and DNA Injury: Good or Evil? The serial presents the latest technologies related to the field of clinical chemistry, and is the benchmark for novel analytical approaches in the clinical laboratory.

Proteomics in Biology, Part B

1st Edition
Volume 586
January 27, 2017
English
Hardback
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eBook
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Proteomics in Biology, Part B, the latest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in proteomics.

Sterol Regulation of Ion Channels

1st Edition
Volume 80
August 29, 2017
English
Hardback
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eBook
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Sterol Regulation of Ion Channels, Volume 80, the latest in the Current Topics in Membranes series provides outstanding content to the scientific community on relevant topics that relate to the broad field of membranes. Topics of note in this new release include Membrane structure and general mechanisms of sterol regulation of ion channels, the Regulation of ion channels by sterols as boundary lipids, the Differential effects of sterols on ion channels: specific vs. non-specific interactions, the Structural determinants of cholesterol-ion channels interactions, and the Regulation of Ca2+-sensitive K+ channels by cholesterol and bile acids via distinct channel subunits and sites, amongst other specialized chapters. The serial is targeted towards scientists and researchers in biochemistry and molecular and cellular biology, providing the necessary membrane research to assist them in discovering the current state of a particular field. The authors and editors associated with the Current Topics in Membranes series are recognized as world-renowned scientists in their respective fields, making CTM one of the premier serials on membranes

New Pesticides and Soil Sensors

1st Edition
February 10, 2017
Alexandru Mihai Grumezescu
English
Hardback
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eBook
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New Pesticides and Soil Sensors, a volume in the Nanotechnology in the Agri-Food Industry series, is a practical resource that demonstrates how nanotechnology is a highly attractive tool that offers new options for the formulation of ‘nanopesticides’. Recent advances in nanopesticide research is reviewed and divided into several themes, including improvement of the water solubility of poorly soluble pesticide active ingredients to improve bioavailability and the encapsulation of pesticide active ingredients within permeable nanoparticles with the aim of releasing pesticide active ingredients in a controlled or targeted manner, while also protecting active ingredients from premature photo-degradation.

Pharmacology of Cholinergic and Adrenergic Transmission

1st Edition
January 31, 2017
G. B. Koelle + 2 more
English
Paperback
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eBook
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Section on Pharmacology of the International Union of Physiological Sciences (SEPHAR), Proceedings of the Second International Pharmacological Meeting, August 20-23, 1963, Volume 3: Pharmacology of Cholinergic and Adrenergic Transmission focuses on the effects of drugs on muscles, nerve fibers, and the central nervous system. The selection first offers information on the role of sodium ions in the release of acetylcholine and the distribution and release of acetylcholine in muscles. Discussions focus on the effects of sodium deficiency on ACh release in perfused ganglia; effects of sodium pump inhibitors on ganglionic and myoneural transmission; distribution of ACh and choline acetylase in muscle; and ACh release after denervation. The text then ponders on the roles of acetylcholine and acetylcholinesterase in junctional transmission and correlated studies of monoamines and acetylcholinesterase in sympathetic ganglia, manifesting the distribution of adrenergic and cholinergic neurons. The publication examines the action of acetylcholine and related drugs on mammalian nonmyelinated nerve fibers; possible mechanisms of acetylcholine action in muscles; and electrophysiological analysis of cholinergic transmission in sympathetic ganglia. The text then reviews the interactions of cholinomimetic and cholinergic blocking drugs at sympathetic ganglia; evolution of cholinoreceptive sites of locomotor muscle; and pharmacological blocking of central cholinoreactive systems and the possibilities of its therapeutic application. The selection is a dependable source of data for readers interested in the pharmacology of cholinergic and adrenergic transmission.

Biosynthesis & Integration of Cell Metabolism

1st Edition
December 20, 2017
B C Currell + 1 more
English
Paperback
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eBook
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Biotechnology by Open Learning: Biosynthesis and the Integration of Cell Metabolism focuses on the structure and activities of cells, including nitrogen fixation, biosynthesis, and metabolic pathways. The manuscript takes a look at precursor molecules for biosynthesis, uptake of nutrients, and nitrogen and sulfur assimilation. Discussions focus on the importance of nitrogen fixation in nature, assimilation of sulfate, ammonia, nitrate, and molecular nitrogen, passive diffusion through protein channels, nutritional requirements of cells, and membranes as permeability barriers. The book then explores amino acid and nucleotide biosynthesis and biosynthesis of lipids. Topics include commercial importance of polysaccharides of micro-organisms, biosynthesis of disaccharides, oligosaccharides and polysaccharides, occurrence of carbohydrates in living systems, and metabolic links between amino acid biosynthesis and the biosynthesis of purines and pyrimidines. The text examines the integration and regulation of metabolism and control of metabolic pathway flux, including patterns of regulation of metabolic pathways, coupling agents in metabolism, integration and regulation of metabolism, and maintenance of metabolic homeostasis through energy coupling. The manuscript is a valuable source of data for biotechnologists and researchers interested in biosynthesis and integration of cell metabolism.

Health Reform Policy to Practice

1st Edition
August 4, 2017
Ronald Stock + 1 more
English
Paperback
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eBook
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Health Reform Policy to Practice: Oregon as a Case Study for a Path to a Comprehensive and Sustainable Health Delivery Model offers a real world example of an innovative, successful and comprehensive program conducted by the U.S. State of Oregon. In 1991, Oregon embarked on a journey to improve health for all its citizens by radically re-thinking how to approach health care for long-term benefits. Over more than two decades, Oregonians have participated in a dialogue to create a new approach to solve the dilemma of providing high quality health care that is affordable and effective. Traditionally, health care reform looked at cutting people from care, cutting provider rates or cutting services. Oregon’s approach is unique in that it built a new system of delivery from the ground (community) up. The Oregon model took a “Fourth Path” to health care by redesigning the clinical delivery system through reducing waste, improving individual health and prevention, and therefore reducing utilization of services, creating local accountability, aligning financial incentives and creating fiscal accountability. This is not only an Oregon story, but a national one as other states, payers and purchasers implement health care reform.

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