Life sciences print books and ebooks | Elsevier

Comprehensive Toxicology

3rd Edition
December 1, 2017
Charlene McQueen
English
Hardback
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eBook
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Comprehensive Toxicology, Third Edition, Fifteen Volume Set discusses chemical effects on biological systems, with a focus on understanding the mechanisms by which chemicals induce adverse health effects. Organized by organ system, this comprehensive reference work addresses the toxicological effects of chemicals on the immune system, the hematopoietic system, cardiovascular system, respiratory system, hepatic toxicology, renal toxicology, gastrointestinal toxicology, reproductive and endocrine toxicology, neuro and behavioral toxicology, developmental toxicology and carcinogenesis, also including critical sections that cover the general principles of toxicology, cellular and molecular toxicology, biotransformation and toxicology testing and evaluation. Each section is examined in state-of-the-art chapters written by domain experts, providing key information to support the investigations of researchers across the medical, veterinary, food, environment and chemical research industries, and national and international regulatory agencies. Thoroughly revised and expanded to 15 volumes that include the latest advances in research, and uniquely organized by organ system for ease of reference and diagnosis, this new edition is an essential reference for researchers of toxicology.

Applications of Mass Spectrometry Imaging to Cancer

1st Edition
Volume 134
January 19, 2017
English
Hardback
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eBook
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Applications of Mass Spectrometry Imaging to Cancer, the latest volume in the Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. This volume presents original reviews on applications of mass spectrometry imaging to cancer.

zika virus disease

1st Edition
November 13, 2017
Adnan I. Qureshi
English
Paperback
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eBook
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Zika Virus provides an authoritative account of one of most fascinating viruses of the 21st century, covering all the main points. It includes coverage of clinical manifestations, such as fever and fatigue, but also delves into neurological manifestations like acute demyelinating neuropathy. In addition, the book discusses new evidence that suggests that Zika fever in pregnant women can cause abnormal brain development in fetuses by mother-to-child transmission. The Zika virus infection has become one of the first where women are actively discouraged from getting pregnant. Readers will find this book to be a comprehensive resource on the topic.

Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids

1st Edition
April 4, 2017
Surendra Nimesh + 2 more
English
Hardback
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eBook
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Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids addresses several issues related to safe and effective delivery of nucleic acids (NAs) using nanoparticles. A further emphasis would be laid on the mechanism of delivery of NAs, the barriers encountered and the strategies adapted to combat them. An exhaustive account of the advantages as well shortcomings of all the delivery vectors being employed in delivery of various NAs will be provided. On final note the regulatory aspects of nanoparticles mediated NA would be discussed, with focus on their clinical relevance. The design and development of nucleic acid-based therapeutics for the treatment of diseases arising from genetic abnormalities has made significant progress over the past few years. NAs have been widely explored for the treatment of cancer and infectious diseases or to block cell proliferation and thereby caused diseases. Advances in synthetic oligonucleotide chemistry resulted in synthesis of NAs that are relatively stable in in vivo environments. However, cellular targeting and intracellular delivery of NAs still remains a challenge. Further development of NA-based therapeutics depends on the progress of safe and effective carriers for systemic administration. Nanomedicine has facilitated availability of vectors with diminished cytotoxicity and enhanced efficacy which are rapidly emerging as systems of choice. These vectors protect NAs from enzymatic degradation by forming condensed complexes along with targeted tissue and cellular delivery. During the past few years, a myriad reports have appeared reporting delivery of NAs mediated by nanoparticles. This book will provide an overview of nanoparticles being employed in the in vitro and in vivo delivery of therapeutically relevant NAs like DNA, siRNA, LNA, PNA, etc.

Handbook of Advanced Chromatography /Mass Spectrometry Techniques

1st Edition
September 7, 2017
Michal Holcapek + 1 more
English
Paperback
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eBook
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Handbook of Advanced Chromatography /Mass Spectrometry Techniques is a compendium of new and advanced analytical techniques that have been developed in recent years for analysis of all types of molecules in a variety of complex matrices, from foods to fuel to pharmaceuticals and more. Focusing on areas that are becoming widely used or growing rapidly, this is a comprehensive volume that describes both theoretical and practical aspects of advanced methods for analysis. Written by authors who have published the foundational works in the field, the chapters have an emphasis on lipids, but reach a broader audience by including advanced analytical techniques applied to a variety of fields. Handbook of Advanced Chromatography / Mass Spectrometry Techniques is the ideal reference for those just entering the analytical fields covered, but also for those experienced analysts who want a combination of an overview of the techniques plus specific and pragmatic details not often covered in journal reports. The authors provide, in one source, a synthesis of knowledge that is scattered across a multitude of literature articles. The combination of pragmatic hints and tips with theoretical concepts and demonstrated applications provides both breadth and depth to produce a valuable and enduring reference manual. It is well suited for advanced analytical instrumentation students as well as for analysts seeking additional knowledge or a deeper understanding of familiar techniques.

Schering Symposium on Intrinsic and Extrinsic Factors in Early Mammalian Development, Venice, April 20 to 23, 1970

1st Edition
February 22, 2017
Gerhard Raspé
English
Paperback
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eBook
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Advances in the Biosciences 6: Schering Symposium on Intrinsic and Extrinsic Factors in Early Mammalian Development, Venice, April 20 to 23, 1970 is a collection of papers presented at the Schering Symposium on Intrinsic and Extrinsic Factors in Early Mammalian Development, held in Venice, Italy, on April 20-23, 1970. Contributors explore intrinsic and extrinsic mechanisms underlying early development in mammals and cover topics ranging from transmission of maternal proteins into oocytes to normal and abnormal fertilization in mammals; experimental early parthenogenesis in mammals; and nutrient requirements for the culture of preimplantation embryos in vitro. This book is comprised of 33 chapters and begins with an overview of the oocyte and the egg, touching on subjects such as electron microscopy of the primary and secondary oocyte; experimental early parthenogenesis in mammals; and laparoscopic recovery of pre-ovulatory human oocytes after priming of the ovaries with gonadotrophins. The next section is devoted to intrinsic and extrinsic influence on the metabolism of preimplantation embryos and includes chapters dealing with the composition of oviductal and uterine fluids; the role of uterine proteins in embryonic development; sex chromosome markers as indicators in embryonic development; and manipulations of the blastocyst. The remaining chapters examine placental and fetal physiology, immunology and teratology, and differentiation of tissues. This monograph will be of interest to biologists and physiologists.

Understanding Food Systems

1st Edition
May 25, 2017
Ruth MacDonald + 1 more
English
Paperback
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eBook
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Understanding Food Systems: Agriculture, Food Science, and Nutrition in the United States explores the complex and evolving system from which the United States gets its food. From farm, to home, and everything in-between, the authors use a scientific perspective that explains the fundamentals of agricultural production, food science, and human nutrition that will guide readers through the issues that shape our food system, including political, societal, environmental, economic, and ethical concerns. Presenting the role and impact of technology, from production to processing and safety, to cultural and consumer behavior perspectives, the book also explores the link between food systems and the history of nutrients and diet patterns, and how these influence disease occurrence. Current topics of concern and debate, including the correlations between food systems and diet-related diseases, such as obesity and diabetes are explored, as are the history and current status of food insecurity and accessibility. Throughout the text, readers are exposed to current topics that play important roles in personal food choices and how they influence components of the food system.

Smart Technologies for Sustainable Smallholder Agriculture

1st Edition
April 7, 2017
David Chikoye + 2 more
English
Paperback
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eBook
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Smart Technologies for Sustainable Smallholder Agriculture: Upscaling in Developing Countries defines integrated climate smart agricultural technologies (ICSAT) as a suite of interconnected techniques and practices that enhance quantity and quality of agricultural products with minimum impact on the environment. These ICSAT are centered on three main pillars, increased production and income, adaptation and resilience to climate change, and minimizing GHG emissions. This book brings together technologies contributing to the three pillars, explains the context in which they can be scaled up, and identifies research and development gaps as areas requiring further investigation. It stresses the urgency in critically analyzing and recommending ICSAT and scaling out the efforts of both developing and disseminating these in an integrated manner. The book discusses, synthesizes, and offers alternative solutions to agriculture production systems and socio-economic development. It brings together biophysical and socioeconomic disciplines in evaluating suitable ICSAT in an effort to help reduce poverty and food insecurity.

Neuroscience Basics

1st Edition
May 25, 2017
Jennifer L. Larimore
English
Paperback
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eBook
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Neuroscience Basics: A Guide to the Brain’s Involvement in Everyday Activities examines how our brain works in everyday activities like sleeping, eating, love, and exercise. Many want to better understand how the brain works, but the terminology and jargon of books can be overwhelming. The book covers the basics taught in an introductory neurobiology course designed for anyone new to the neuroscience field, including non-neuroscientists. While each of the chapters explore the brain in a normal state, Neuroscience Basics also discusses disruptions of the normal state—psychosis, Alzheimer’s, Parkinson’s, autism, learning disorders, etc. This book breaks down the topics into language that is more accessible while making the neuroscience topics fun and relevant.

Beyond Agricultural Impacts

1st Edition
June 20, 2017
Nkulumo Zinyengere + 3 more
English
Paperback
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eBook
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Beyond Agricultural Impacts: Multiple Perspectives on Climate Change in Africa presents the theories and methods commonly applied in climate change assessment from various locations in Africa, also inspiring further research that addresses the broad spectrum of societal impacts that result from altered climate status. Using case studies, the work provides insights into climate change impacts and adaptation with a lens on vulnerable groups in African agriculture, e.g. smallholder crop and livestock farmers, women and youth. The book also highlights areas of further interest in climate change and agriculture research in Africa, all done through views from multiple disciplines in the agriculture and climate change nexus.

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