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Elsevier

Books in Life sciences

  • Multivariate Analyses of Codon Usage Biases

    • 1st Edition
    • Jean R. Lobry
    • English
    A complete case study with all coding sequences from the bacteria Borrellia burgdorferi illustrates how multivariate analyses reveals evolutionary mechanisms acting at the molecular level. They are either mutationnal (symmetric and asymmetric directionnal mutation pressure) or selective (selection against head-on collisions or linked to gene expressivity or subcellular location).

  • Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics

    Clinical Principles and Applications
    • 7th Edition
    • Reed E. Pyeritz + 2 more
    • English
    For decades, Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics has served as the ultimate resource for clinicians integrating genetics into medical practice. With detailed coverage in contributions from over 250 of the world’s most trusted authorities in medical genetics and a series of 11 volumes available for individual sale, the Seventh Edition of this classic reference includes the latest information on seminal topics such as prenatal diagnosis, genome and exome sequencing, public health genetics, genetic counseling, and management and treatment strategies to complete its coverage of this growing field for medical students, residents, physicians, and researchers involved in the care of patients with genetic conditions. This comprehensive yet practical resource emphasizes theory and research fundamentals related to applications of medical genetics across the full spectrum of inherited disorders and applications to medicine more broadly.Clinical Principles and Applications thoroughly addresses general methods and approaches to genetic counseling, genetic diagnostics, treatment pathways, and drug discovery. Additionally, new and updated chapters explore the clinical implementation of genomic technologies, analytics, and therapeutics, with special attention paid to developing technologies, common challenges, patient care, and ethical and legal aspects.With regular advances in genomic technologies propelling precision medicine into the clinic, the seventh edition of Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics bridges the gap between high-level molecular genetics and practical application and serves as an invaluable clinical tool for the health professionals and researchers.

  • Atlas of the Anatomy of Dolphins and Whales

    • 1st Edition
    • Stefan Huggenberger + 2 more
    • English
    Atlas of the Anatomy of Dolphins and Whales is a detailed, fully illustrated atlas on the anatomy and morphology of toothed and whalebone whales. The book provides basic knowledge on anatomical structures, in particular, soft tissues, and functions as a standalone reference work for dissecting rooms and labs, and for those sampling stranded and by-caught dolphins in the field. As a companion and supplement to Anatomy of Dolphins: Insights into Body Structure and Function, this atlas will be of great interest to the scientific community, including veterinarians and biologists, as a book of reference. With a modern approach to dolphin anatomy and morphology, this atlas provides the extensive knowledge necessary to practitioners and theoretical scientists such as evolutionary biologists. The conceptual clarity, precision, and comprehensive and updated display of the topographical anatomy of the body of cetaceans in the atlas support and illustrate the authors’ related work, serving as a comprehensive reference for those who are more specifically interested in the details of the anatomy and morphology of porpoises, dolphins and whales.

  • Progress in Molecular Biology and Translational Science

    • 1st Edition
    • Volume 160
    • English
    Progress in Molecular Biology and Translational Science, Volume 160 provides the most topical, informative and exciting monographs available on a wide variety of research topics related to prions, viruses, bacteria and eukaryotes. The series gives in-depth knowledge on the important molecular biological aspects of organismal physiology and function, along with insights on how this knowledge can be applied to understand and ameliorate human disease. This updated release covers Clinical Drugs in the Environment, Group I Intron Trans-Splicing, Adult Stem Cells on Regenerative Therapy, CRISPR in Animals and Animal Models, The Role of 3’–5’Exoribonuclease... in RNA Degradation, and more.

  • Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics

    Foundations
    • 7th Edition
    • Reed E. Pyeritz + 2 more
    • English
    For decades, Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics has served as the ultimate resource for clinicians integrating genetics into medical practice. With detailed coverage in contributions from over 250 of the world’s most trusted authorities in medical genetics and a series of 11 volumes available for individual sale, the Seventh Edition of this classic reference includes the latest information on seminal topics such as prenatal diagnosis, genome and exome sequencing, public health genetics, genetic counseling, and management and treatment strategies to complete its coverage of this growing field for medical students, residents, physicians, and researchers involved in the care of patients with genetic conditions. This comprehensive yet practical resource emphasizes theory and research fundamentals related to applications of medical genetics across the full spectrum of inherited disorders and applications to medicine more broadly. This volume, Foundations, summarizes basic theories, concepts, research areas, and the history of medical genetics, providing a contextual framework for integrating genetics into medical practice. In this new edition, clinically oriented information is supported by full-color images and expanded sections on the foundations of genetic analytics, next generation sequencing, and therapeutics. With regular advances in genomic technologies propelling precision medicine into the clinic, Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics: Seventh Edition bridges the gap between high-level molecular genetics and practical application and serves as an invaluable clinical tool for the health professionals and researchers.

  • Statistical Methods for Overdispersed Count Data

    • 1st Edition
    • Jean-Francois Dupuy
    • English
    Statistical Methods for Overdispersed Count Data provides a review of the most recent methods and models for such data, including a description of R functions and packages that allow their implementation. All methods are illustrated on datasets arising in the field of health economics. As several tools have been developed to tackle over-dispersed and zero-inflated data (such as adjustment methods and zero-inflated models), this book covers the topic in a comprehensive and interesting manner.

  • Statistical, Mapping and Digital Approaches in Healthcare

    • 1st Edition
    • Gilles Maignant + 1 more
    • English
    Statistical, Mapping and Digital Approaches in Healthcare addresses all health territories, starting from the analysis of geographical data (health data, population data, health data systems and environmental data), to new health areas (Health 3.0), i.e. digital health territories. Specific tools are used to question environmental changes, such as health statistics, mapping, mathematical models, optimization models and serious games.

  • The Common Marmoset in Captivity and Biomedical Research

    • 1st Edition
    • Robert P. Marini + 4 more
    • English
    The Common Marmoset in Captivity and Biomedical Research is the first text dedicated exclusively to this species,filling an urgent need for an encyclopedic compilation of the existing information. Sponsored by the AmericanCollege of Laboratory Animal Medicine as part of its authoritative Blue Book series, the book covers the biology,management, diseases, and clinical and research applications of this important species. The common marmoset(Callithrix jacchus) has come of age in the scientific community as a behaviorally complex, cognitively advanced,small, prolific, and easily maintained nonhuman primate with many of the advantages of larger animals, such asmacaques, but without the attendant physical and zoonotic risks. Marmosets are currently being used in diverse areas of inquiry, including vision and auditory research, infectious disease, cognitive neuroscience, behavior, reproductive biology, toxicology and drug development, and aging. Themarmoset genome has been sequenced and there is currently an intensive effort to apply gene editing technologies to the species. The creation of transgenic marmosets will provide researchers with a small nonhuman primatemodel to study a number of poorly understood disorders, like autism.

  • Applications of Genetic and Genomic Research in Cereals

    • 1st Edition
    • Thomas Miedaner + 1 more
    • English
    Applications of Genetic and Genomic Research in Cereals covers new techniques for practical breeding, also discussing genetic and genomic approaches for improving special traits. Additional sections cover drought tolerance, biotic stress, biomass production, the impact of modern techniques on practical breeding, hybrid breeding, genetic diversity, and genomic selection. Written by an international team of top academics and edited by an expert in the field, this book will be of value to academics working in the agricultural sciences and essential reading for professionals working in plant breeding.

  • Lung Function Testing in the 21st Century

    Methodologies and Tools Bridging Engineering to Clinical Practice
    • 1st Edition
    • Clara Ionescu
    • English
    Lung Function Testing in the 21st Century: Methodologies and Tools Bridging Engineering to Clinical Practice covers the complete aspects of lung function testing, ranging from standardized to newly introduced (IOS, FOT) methods. It provides an updated overview of advances in respiratory engineering, along with advice on which lung function tests are appropriate for which purpose. The author discusses non-standardized lung function testing, methods, clinical tests, diagnosis and future perspectives. Lung function measurement devices and protocols are also covered. This book covers multidisciplinary domains, bringing new technology ideas from mathematics, physics, biology and engineering into the field of respiratory engineering. Users will find a single resource that brings together all of the disparate information on lung function testing technology currently contained in many journal articles.

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