Life sciences print books and ebooks | Elsevier

DNA Repair Enzymes: Structure, Biophysics, and Mechanism

1st Edition
Volume 592
June 29, 2017
English
Hardback
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eBook
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DNA Repair Enzymes, Part B, Volume 592 is the latest volume in the Methods in Enzymology series and the first part of a thematic that focuses on DNA Repair Enzymes. Topics in this updated volume include MacroBac: New Technologies for Robust and Efficient Large-Scale Production of Recombinant Multiprotein Complexes, Production and Assay of Recombinant Multisubunit Chromatin Remodeling Complexes, Analysis of Functional Dynamics of Modular Multidomain Proteins by SAXS and NMR, the Use of Single-Cysteine Variants for Trapping Transient States in DNA Mismatch Repair, and Structural Studies of RNases H2 as an Example of Crystal Structure Determination of Protein-Nucleic Acid Complexes.

A Text-Book of Medical Jurisprudence and Toxicology

1st Edition
May 23, 2017
Rai Bahadur Jaising P. Modi
English
Paperback
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Hardback
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eBook
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Medical Jurisprudence and Toxicology for India covers some essential details and practical aspects of medical jurisprudence and toxicology. This book is organized into two part encompassing 34 chapters. The opening chapters of Part I deal with legal procedure in criminal courts, physical evidence of the crime, autopsy, exhumation, and some medico-legal practices. Considerable chapters are devoted to other aspects of legal medicine, including determination of death causation, legitimacy of evidence, incident of rape and unnatural offenses, miscarriage, infanticide, insanity, and the privileges of medical men. Part II focuses on the toxicological aspects. This part emphasizes the medico-legal aspects of some classes of poisons, such as corrosive, irritant, neurotic, cerebral, spinal, cardiac, and peripheral poisons. This book will prove useful to medical college students.

A Comprehensive and Practical Guide to Clinical Trials

1st Edition
June 7, 2017
Delva Shamley + 1 more
English
Paperback
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eBook
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A Comprehensive and Practical Guide to Clinical Trials provides an overview of the entire process of clinical research in one thorough and easy-to-read handbook that offers those involved in clinical research a clear understanding of how the components of a study are related. It focuses on the practical aspects of the preparation and execution of a clinical trial and offers tools and resources to help the entire team understand how their responsibilities tie together with the tasks and duties of other members. This allows for better planning and prioritization, and can lead to more effective and successful clinical trials. With practical examples, checklists and forms, this book is a useful guide for planning and conducting clinical trials from beginning to end.

Gastrointestinal Tissue

1st Edition
May 10, 2017
Jordi Gracia-Sancho + 1 more
English
Hardback
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eBook
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Gastrointestinal Tissue: Oxidative Stress and Dietary Antioxidants brings together leading experts from world renowned institutions, combining the basic mechanisms of gastrointestinal diseases with information regarding new and alternative treatments. The processes within the science of oxidative stress are described in concert with other processes, including apoptosis, cell signaling and receptor mediated responses, further recognizing that diseases are often multifactorial with oxidative stress as a component. By combining the critical molecular processes underlying free radical mediated pathologies and the role of dietary antioxidant molecules, a connection is made that helps advance therapies and the prevention of gastrointestinal pathological processes. This important reference is well designed with two complementary sections. Section One, Oxidative Stress and Gastroenterology, covers the basic processes of oxidative stress from molecular biology to whole organs, the gastrointestinal anatomy and sources of oxidative stress and free radicals and their products in gastrointestinal diseases. Section Two, Antioxidants and Gastroenterology covers antioxidants in foods, including plants and components.

Sports Neurology, An Issue of Neurologic Clinics

1st Edition
Volume 35-3
July 11, 2017
Tad Seifert
English
Hardback
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eBook
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This issue of Neurologic Clinics, Edited by Dr. Tad Seifert, will do a comprehensive review of Sports Neurology. Some of the topics discussed in the issue include, but are not limited to: Biomechanical Aspects of Sports-Related Head Injuries; Peripheral Nerve Injuries in Sport; CNS Performance Enhancing Drugs in Sport, Sleep, Recovery, and Performance in Sport; Pathophysiology of Sports-Related Concussion; Neurologic Injuries in Noncontact Sports; Neuropsychological Screening in Concussion; Neurosurgical Emergencies in Sport; Psychiatric Comorbidities in Sport; and Biomarkers and Their Role in Sport-Related Head Trauma, among others.

Overflow Metabolism

1st Edition
October 16, 2017
Alexei Vazquez
English
Paperback
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eBook
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Overflow Metabolism: From Yeast to Marathon Runners provides an overview of overflow metabolism, reviewing the major phenomenological aspects as observed in different organisms, followed by a critical analysis of proposed theories to explain overflow metabolism. In our ideal view of metabolism, we think of catabolism and anabolism. In catabolism nutrients break down to carbon dioxide and water to generate biochemical energy. In anabolism nutrients break down to generate building blocks for cell biosynthesis. Yet, when cells are pushed to high metabolic rates they exhibit incomplete catabolism of nutrients, with a lower energy yield and excretion of metabolic byproducts. This phenomenon, characterized by the excretion of metabolic byproducts that could otherwise be used for catabolism or anabolism, is generally known as overflow metabolism. Overflow metabolism is a ubiquitous phenotype that has been conserved during evolution. Examples are the acetate switch in the bacterium E. coli, Crabtree effect in unicellular eukaryote yeasts, the lactate switch in sports medicine, and the Warburg effect in cancer. Several theories have been proposed to explain this seemingly wasteful phenotype. Yet, there is no consensus about what determines overflow metabolism and whether it offers any selective advantage.

Board Review in Preventive Medicine and Public Health

1st Edition
July 4, 2017
Gregory M. Schwaid
English
Paperback
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eBook
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Board Review in Preventive Medicine and Public Health prepares physicians for their initial and recertification board exams in the related specialties of preventive, occupational and aerospace medicine. Formatted in a question and answer based style that imitates material on specialty exams, each question is linked to a detailed answer. The book contains over 640 question and answer sets covering areas such as general public health, health management, health law, community health, infectious disease, clinical preventive medicine, occupational medicine, aerospace medicine, environmental medicine, correctional (prison) medicine, emergency preparedness, epidemiology and biostatistics. The book is an essential board preparation for physicians with a background in the fields of preventive medicine, occupational medicine, and aerospace medicine. It is also useful for medical students, public health students and those wishing to gain an understanding of the key points in these fields.

Connected Objects in Health

1st Edition
August 8, 2017
Laure Beyala
English
Hardback
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eBook
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Connected objects today present a range of opportunities in medicine. We live in a new digital era where the monitoring and analysis of one’s own health information no longer belongs solely to the realm of science fiction. The success of these new devices resides in their usage, which integrates seamlessly into the daily life of the user in order to continually collect the maximum amount of data. These medical connected devices therefore constitute a new hope in transforming user experience as well as the care pathway. They offer a better level of support and a better quality of life for those suffering from chronic illnesses or mental, sensorial or physical disabilities. However, these solutions also pose systematic problems, especially regarding the risks linked to their usage. This book presents a cartography which clearly details all the potential risk scenarios linked to the usage of connected devices as well as the actions which should be undertaken to promote balanced governance and guarantee the development of high-quality medical devices.

Psychometrics and Psychological Assessment

1st Edition
June 19, 2017
Carina Coulacoglou + 1 more
English
Hardback
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eBook
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Psychometrics and Psychological Assessment: Principles and Applications reports on contemporary perspectives and models on psychological assessment and their corresponding measures. It highlights topics relevant to clinical and neuropsychological domains, including cognitive abilities, adaptive behavior, temperament, and psychopathology.More... the book examines a series of standard as well as novel methods and instruments, along with their psychometric properties, recent meta-analytic studies, and their cross-cultural applications.

Cancer and Noncoding RNAs

1st Edition
Volume 1
October 2, 2017
Jayprokas Chakrabarti + 1 more
English
Hardback
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eBook
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Cancer and Noncoding RNAs offers an in-depth exploration of noncoding RNAs and their role in epigenetic regulation of complex human disease, most notably cancer. In addition to examining microRNAs, this volume provides a unique evaluation of more recently profiled noncoding RNAs now implicated in carcinogenesis, including lncRNAs, piRNAs, circRNAs, and tRNAs, identifying differences in function between these noncoding RNAs and how they interact with the rest of the epigenome. A broad range of chapters from experts in the field detail epigenetic regulation of various cancer types, along with recent next generation sequencing technologies, genome-wide association studies (GWAS) and bioinformatics approaches. This book will help researchers in genomic medicine and cancer biology better understand the role of noncoding RNAs in epigenetics, aiding in the development of useful biomarkers for diagnosis, prognosis and new RNA-based disease therapies.

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