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Elsevier

Books in Life sciences

  • Reproducibility in Biomedical Research

    Epistemological and Statistical Problems
    • 1st Edition
    • Erwin B. Montgomery Jr.
    • English
    Reproducibility in Biomedical Research: Epistemological and Statistical Problems explores the ideas and conundrums inherent in scientific research. It explores factors of reproducibility, including logic, distinguishing productive from unproductive irreproducibility, the scientific method, and the use of statistics. In multiple examples and six detailed case studies, the book demonstrates the misuse of logic resulting in unproductive irreproducibility, allowing researchers to develop their own logic and planning abilities. Biomedical researchers, clinicians, administrators of scientific institutions and funding agencies, journal editors, philosophers of science and medicine will find the arguments and explorations a valuable addition to their libraries.

  • EEG-Based Brain-Computer Interfaces

    Cognitive Analysis and Control Applications
    • 1st Edition
    • Dipali Bansal + 1 more
    • English
    EEG-Based Brain-Computer Interface: Cognitive Analysis and Control Applications provides a technical approach to using brain signals for control applications, along with the EEG-related advances in BCI. The research and techniques in this book discuss time and frequency domain analysis on deliberate eye-blinking data as the basis for EEG-triggering control applications. In addition, the book provides experimental scenarios and features algorithms for acquiring real-time EEG signals using commercially available units that interface with MATLAB software for acquisition and control.

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 58
    • English
    Progress in Medicinal Chemistry, Volume 58, provides a review of eclectic developments in medicinal chemistry, with each chapter written by an international board of authors. Topics covered in this new release include Amyotrophic lateral sclerosis (ALS), Covalent-binding Drugs, Natural Product Drug Delivery – A Special Challenge?, and SMN2 gene splicing modifier, and more.

  • Highlighting Operational and Implementation Research for Control of Helminthiasis

    • 1st Edition
    • Volume 103
    • English
    Highlighting Operational and Implementation Research for Control of Helminthiasis, Volume 103 in the Advances in Parasitology series, includes medical studies of parasites of major influence, along with reviews of more traditional areas, such as zoology, taxonomy and life history, all topics which help to shape current thinking and applications. This latest release includes chapters on Helminthiasis Epidemiology and Control: Scoring Successes and Meeting the Remaining Challenges, Worms, History and Swiss TPH, Mobile Microscopy, Combination Chemotherapy, DNDi Portfolio, Pediatric Praziquantel, lessons learned, and Community and Drug Distributor Perceptions and Experiences of Mass Drug Administration for the Elimination of Lymphatic Filariasis, amongst other topics.

  • Handbook of Sleep Disorders in Medical Conditions

    • 1st Edition
    • Josee Savard + 1 more
    • English
    Handbook of Sleep Disorders in Medical Conditions reviews the current knowledge on the nature and manifestations of sleep disorders associated with a variety of common medical conditions, including epilepsy, traumatic brain injury and dementia. It also provides clinical guidelines on how to assess and treat them with pharmacological and non-pharmacological interventions. Although the general principles of sleep medicine may be applied to some extent to patients with comorbid medical conditions, this book makes the case that an adaptive approach is warranted when considering the particularities of each condition. In addition, clinicians must also be cautious when prescribing sleep medications as some pharmacological agents are known to exacerbate symptoms associated with the medical condition, such as cognitive deficits (i.e. difficulties with memory and attention) in cancer patients experiencing chemo brain, or in persons with neurologic conditions (e.g. mild cognitive impairment, dementia, stroke, brain injury). A differential approach to evaluating and treating sleep is thus warranted.

  • Genes, Brain Function, and Behavior

    What Genes Do, How They Malfunction, and Ways to Repair Damage
    • 1st Edition
    • Douglas Wahlsten
    • English
    Genes, Brain Function, and Behavior offers a concise description of the nervous system that processes sensory input and initiates motor movements. It reviews how behaviors are defined and measured, and how experts decide when a behavior is perturbed and in need of treatment. Behavioral disorders that are clearly related to a defect in a specific gene are reviewed, and the challenges of understanding complex traits such as intelligence, autism and schizophrenia that involve numerous genes and environmental factors are explored. New methods of altering genes offer hope for treating or even preventing difficulties that arise in our genes. This book explains what genes are, what they do in the nervous system, and how this impacts both brain function and behavior.

  • Ecometabolomics

    Metabolic Fluxes versus Environmental Stoichiometry
    • 1st Edition
    • Sumira Jan + 1 more
    • English
    Ecometabolomics: Metabolic Fluxes versus Environmental Stoichiometry focuses on the interaction between plants—particularly plants that have vigorous secondary metabolites—and the environment. The book offers a comprehensive overview of the responses of the metabolome of organisms to biotic and abiotic environmental changes. It includes an introduction to metabolomics, summaries of metabolomic techniques and applications, studies of stress in plants, and insights into challenges. This is a must-have reference for plant biologists, plant biochemists, plant ecologists and phytochemists researching the interface between plants and the environment using metabolomics.

  • Platelets

    • 4th Edition
    • Alan D. Michelson + 3 more
    • English
    Platelets, Fourth Edition, integrates the entire field of platelet biology, pathophysiology, and clinical medicine with contributions from 142 world experts from 18 countries. This award-winning reference provides clear presentations by basic scientists on the cellular, molecular, and genetic mechanisms of platelets and the role of platelets in thrombosis, hemorrhage, inflammation, antimicrobial host defense, wound healing, angiogenesis and cancer. It also provides start-of-the-art presentations by hematologists, cardiologists, stroke physicians, blood bankers, pathologists and other clinicians on platelet function testing, disorders of platelet numbers and function, antiplatelet therapy and therapy to increase platelet numbers and/or function. Since the publication of the Third Edition of Platelets, there has been a rapid expansion of knowledge in both basic biology of platelets and the clinical approach to platelet-related diseases. This Fourth Edition of Platelets draws all this information into a single, comprehensive and authoritative resource.

  • Anorectal Disorders

    Diagnosis and Non-Surgical Treatments
    • 1st Edition
    • Enrique Coss-Adame + 1 more
    • English
    Anorectal Disorders: Diagnosis and Nonsurgical Treatments incorporates the most recent major advances in the understanding of anal and rectal anatomy to provide clinical evidence of care for those suffering from anorectal disorders. By condensing basic and practical aspects in the knowledge of anorectal disorders, this book provides a comprehensive review of the anatomy and physiology of the anorectal region. It includes new technology that expands and modifies current perceptions about the functional anatomy of the anorectal region and ultimately impacts how we conceive muscle and nerve structures functioning together to maintain fecal continence and properly execute the process of defecation. Perfect for medical researchers, gastroenterologists, general practitioners, internal medicine doctors and general surgeons, this title will provide diagnosis and treatment options for all patients suffering from anorectal disorders.

  • Ubiquitin and Ubiquitin-like Protein Modifiers

    • 1st Edition
    • Volume 618
    • English
    Ubiquitination and Protein Stability - Part A Volume 618, the latest release in the Methods in Enzymology series, highlights new advances in the field, with this updated volume presenting interesting chapter written by an international board of authors. Topics of note in this new release include the Preparation of ubiquitinated nucleosomes with native and non-hydrolyzable linkages, Methods to measure ubiquitin chain length and linkage, Genetic approaches to study the yeast ubiquitin system, Enzymatic preparation of monoubiquitinated proteins, Methods to distinguish the function of ubiquitin in autophagy and the proteasome pathway, the Purification and characterization of enzyme activity of USPs, and much more.

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