Books in Life sciences

Iron Metabolism: Hepcidin

1st Edition
Volume 110
February 22, 2019
Gerald Litwack
English
Hardback
9 7 8 0 1 2 8 1 7 8 4 2 3
eBook
9 7 8 0 1 2 8 1 7 8 4 3 0

Iron Metabolism, Volume 110, the latest release in the Vitamins and Hormones series first published in 1943, covers the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms, with this release focusing on topics relating to hepcidin, bacterial infection, and iron overload, the role of heparan sulfates in hepcidin regulation, hepcidin CDNA and human gene sex hormones, growth factors and hepcidin, HFE gene polymorphisms and hereditary hemochromatosis, hepcidin and il-1beta, hepcidin-ferroportin axis, cardiomyocyte hepcidin, adipocyte iron, leptin and hepcidin, regulators of hepcidin expression, and much more.

Malignant Pleural Mesothelioma

1st Edition
February 21, 2019
Antonio Giordano + 1 more
English
eBook
9 7 8 0 1 2 8 1 2 7 2 5 4

Malignant Pleural Mesothelioma: A Guide for Clinicians is a practical book developed to assist clinicians, pathologist and molecular biologist in the management of malignant pleural mesothelioma (MPM). MPM represents a challenge in terms of diagnosis, staging and treatment, and to date, the optimal management of MPM patients has not yet been clearly defined – and this book is intended to be an efficient tool for these cases. The book encompasses topics such as epidemiology and surveillance evidence, multimodality imaging assessment of MPM, pathology, molecular mechanisms and treatment of such disease. Additionally, it discusses the standard operative procedures and the future directions for the management of MPM from experts’ experiences. Malignant Pleural Mesothelioma: A Guide for Clinicians is a valuable source for oncologists, pathologist, cancer researchers, thoracic specialists and several members of biomedical field who needs to learn more from experts about the diagnosis, operative procedures and treatment of malignant pleural mesothelioma.

Advances in Clinical Chemistry

1st Edition
Volume 89
February 21, 2019
Gregory S. Makowski
English
Hardback
9 7 8 0 1 2 8 1 7 1 4 5 5
eBook
9 7 8 0 1 2 8 1 7 1 4 6 2

Advances in Clinical Chemistry, Volume 89, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, and is the benchmark for novel analytical approaches in the clinical laboratory.

Organ Development

1st Edition
Volume 132
February 20, 2019
Deneen Wellik
English
Hardback
9 7 8 0 1 2 8 1 0 4 8 9 7
eBook
9 7 8 0 1 2 8 1 0 4 9 0 3

Organ Development, Volume 132, the latest release in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapter written by an international board of authors. This volume highlights cogent reviews of the development, maintenance and regeneration/repair of several organ systems, from eye to kidney, to the musculoskeletal system. Many reviews highlight new techniques or technologies that are currently pushing the field. The role of both embryonic and adult stem cells are highlighted and senior authors are all women scientists.

Basic and Applied Bone Biology

2nd Edition
February 20, 2019
David B. Burr + 1 more
English
Hardback
9 7 8 0 1 2 8 1 3 2 5 9 3
eBook
9 7 8 0 1 2 8 1 3 2 6 0 9

Basic and Applied Bone Biology, Second Edition, provides an overview of skeletal biology, from the molecular level, to the organ level, including cellular control, interaction and response, adaptive responses to various external stimuli, and the interaction of the skeletal system with other metabolic processes in the body. The book includes chapters that address how the skeleton can be evaluated through the use of various imaging technologies, biomechanical testing, histomorphometric analysis, and the use of genetically-modified animal models. Each chapter delves deep into the important details of topics covered to provide a solid understanding of the basics of bone biology. Bone biology researchers who also train undergraduate and graduate students in the lab will use this book constantly to orient new students on the basics of the field and as a background reference for many of the technical aspects of qualification in bone biology (e.g., mechanics, histomorphometry, genetic modification, biochemistry, etc.).

DNA Repair

1st Edition
Volume 115
February 20, 2019
Rossen Donev
English
Hardback
9 7 8 0 1 2 8 1 5 5 5 9 2
eBook
9 7 8 0 1 2 8 1 5 5 6 0 8

DNA Repair, Volume 115, the latest release in the Advances in Protein Chemistry and Structural Biology series, provides an overview of current developments in mechanisms underlying DNA repair, their involvement in maintaining chromatin repair, the balance between chromosome breaks repair pathways, tumorigenesis, immune signaling and infection-induced inflammation. Specific chapters cover the Structure and function of the multi-subunit TFIIH with insights into nucleotide excision repair, Chromatin repair: how DNA packaging controls double-strand break repair, Controlling the balance between chromosome breaks repair pathways, The targeting of DNA repair pathways in the era of precision oncology, and much more.

Metabolons and Supramolecular Enzyme Assemblies

1st Edition
Volume 617
February 19, 2019
Claudia Schmidt-Dannert + 1 more
English
Hardback
9 7 8 0 1 2 8 1 7 0 7 4 8
eBook
9 7 8 0 1 2 8 1 7 0 7 5 5

Metabolons and Supramolecular Enzyme Assemblies, Volume 617 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Dynamic plant metabolons, TCA cycle metabolons, the Chemotactic assembly of metabolons, Repurposing peroxisomes for metabolic engineering, Repurposing yeast mitochondria for metabolic engineering, Repurposing plant compartments for metabolic engineering, Protein scaffolds for pathway co-localization on lipid droplets, Engineered enzyme assemblies for metabolic engineering, NRPS assembly lines and P450 interactions, and much more.

Bioarchaeology of Marginalized People

1st Edition
February 18, 2019
Madeleine L. Mant + 1 more
English
Paperback
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eBook
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Bioarchaeology of Marginalized People amplifies the voices of marginalized or powerless individuals. Following previous work done by physical anthropologists on the biology of poverty, this volume focuses on the voices of past actors who would normally be subsumed within a cohort or whose stories represent those of the minority. The physical effects of marginalization – manifest as skeletal markers of stress and disease – are read in their historical contexts to better understand vulnerability and the social determinants of health in the past. Bioarchaeological, archaeological, and historical datasets are integrated to explore the varied ways in which individuals may be marginalized both during and after their lifespan. By focusing on previously excluded voices this volume enriches our understanding of the lived experience of individuals in the past. This volume queries the diverse meanings of marginalization, from physical or social peripheralization, to identity loss within a majority population, to a collective forgetting that excludes specific groups. Contributors to the volume highlight the histories of individuals who did not record their own stories, including two disparate Ancient Egyptian women and individuals from a high-status Indigenous cemetery in British Columbia. Additional chapters examine the marginalized individuals whose bodies comprise the Robert J. Terry anatomical collection and investigate inequalities in health status in individuals from Canada, the United States, and the United Kingdom. Modern clinical population health research is examined through a historical lens, bringing a new perspective to the critical public health interventions occurring today. Together, these papers highlight the role that biological anthropologists play both in contributing to and challenging the marginalization of past populations.

Echinoderms

1st Edition
Volume 150
February 16, 2019
Kathleen Foltz + 1 more
English
Hardback
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eBook
9 7 8 0 1 2 8 1 5 9 5 5 2

Echinoderms, Volume 150 in the Methods in Cell Biology series, highlights new advances in the field, with this update presenting interesting chapters on procuring animals and culturing of eggs and embryos, cryopreservation of sea urchin gametes, emerging echinoderm models, culturing of sand dollars, cidaroids and heart urchins, culturing echinoderm larvae through metamorphosis, microinjection methods, injection of exogenous messages and protein overexpression, blastomere transplantation, visualization of embryonic polarity, larval immune cell approaches, methods for analysis of sea urchin primordial germ cells, and protocols and best practices for toxicology and pH studies using echinoderms and　several new chapters outlining the use of sea urchins in the classroom.

Gap Junction Structure and Chemical Regulation

1st Edition
February 16, 2019
Camillo Peracchia
English
Paperback
9 7 8 0 1 2 8 1 6 1 5 0 0
eBook
9 7 8 0 1 2 8 1 6 3 8 0 1

Gap Junction Structure and Chemical Regulation: Direct Calmodulin Role in Cell-to-Cell Channel Gating describes and discusses the findings of major studies conducted during the past century on the structure and chemical regulation of direct cell-to-cell communication via gap junction channels. Chapters bring together important findings on direct cell communication, from its history, to its structure and regulation. These channels are essential for normal organ function, and mutations in their protein (connexin) cause various diseases. The book is useful for established investigators who need a review on the field and young investigators who need a thorough resource for study and comprehension.

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