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Books in Pharmacology general

111-120 of 317 results in All results

Diversity and Functions of GABA Receptors: A Tribute to Hanns Möhler, Part A

  • 1st Edition
  • Volume 72
  • January 12, 2015
  • Uwe Rudolph
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 8 0 2 6 6 0 - 1
  • eBook
    9 7 8 - 0 - 1 2 - 8 0 2 6 9 2 - 2
This new volume of Advances in Pharmacology presents the diversity and functions of GABA Receptors. The volume looks at research performed in the past 20 years which has revealed specific physiological and pharmacological functions of individual GABAA receptor subtypes, providing novel opportunities for drug development.

Re-Engineering Clinical Trials

  • 1st Edition
  • December 16, 2014
  • Peter Schueler + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 4 2 0 2 4 6 - 7
  • eBook
    9 7 8 - 0 - 1 2 - 8 0 0 7 9 0 - 7
The pharmaceutical industry is currently operating under a business model that is not sustainable for the future. Given the high costs associated with drug development, there is a vital need to reform this process in order to provide safe and effective drugs while still securing a profit. Re-Engineering Clinical Trials evaluates the trends and challenges associated with the current drug development process and presents solutions that integrate the use of modern communication technologies, innovations and novel enrichment designs. This book focuses on the need to simplify drug development and offers you well-established methodologies and best practices based on real-world experiences from expert authors across industry and academia. Written for all those involved in clinical research, development and clinical trial design, this book provides a unique and valuable resource for streamlining the process, containing costs and increasing drug safety and effectiveness.

Side Effects of Drugs Annual

  • 1st Edition
  • Volume 36
  • December 1, 2014
  • Sidhartha D. Ray
  • English
  • Hardback
    9 7 8 - 0 - 4 4 4 - 6 3 4 0 7 - 8
  • eBook
    9 7 8 - 0 - 4 4 4 - 6 3 3 9 1 - 0
The Side Effects of Drugs Annual was first published in 1977. It has been continually published since then as a yearly update to the voluminous encyclopedia Meyler's Side Effects of Drugs. Each new Annual continues to provide clinicians and medical investigators with a reliable and critical yearly survey of new data and trends in the area of adverse drug reactions and interactions. An international team of specialists has contributed to the informative Annual by critically interpreting it and by pointing to whatever is misleading.

Pharmacology of the Blood Brain Barrier: Targeting CNS Disorders

  • 1st Edition
  • Volume 71
  • September 19, 2014
  • Thomas P Davis
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 8 0 0 2 8 2 - 7
  • eBook
    9 7 8 - 0 - 1 2 - 8 0 0 3 3 8 - 1
This new volume of Advances in Pharmacology presents pharmacology of the blood brain barrier, focusing on targeting CNS disorders. With a variety of chapters and the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike.

Proteomics in Biomedicine and Pharmacology

  • 1st Edition
  • Volume 95
  • June 24, 2014
  • Rossen Donev
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 8 0 0 4 5 3 - 1
  • eBook
    9 7 8 - 0 - 1 2 - 8 0 0 5 9 5 - 8
Volume 95 of Advances in Protein Chemistry and Structural Biology focuses on advances in proteomic techniques and their application in biomedicine and pharmacology. This volume describes in detail the applications of these techniques in studying a number of diseases and specific protein modifications and profiles, including phosphoproteomics, glycoproteomics, and more. Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology series is the essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins. Each thematically organized volume is guest edited by leading experts in a broad range of protein-related topics.

Biased Signaling in Physiology, Pharmacology and Therapeutics

  • 1st Edition
  • June 5, 2014
  • Brian J Arey
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 4 1 1 4 6 0 - 9
  • eBook
    9 7 8 - 0 - 1 2 - 4 1 1 5 0 7 - 1
Biased Signaling in Physiology, Pharmacology and Therapeutics is a unique and essential reference for the scientific community concerning how conformational-dependent activation is a common phenomenon across many classes of receptors or signaling molecules. It discusses the role of conformational dynamics in leading to signaling bias across different classes of receptors and signaling molecules. By providing a broader view of signaling bias, this resource helps to explain common mechanisms shared across receptor classes and how this can be utilized to elucidate their cellular activity and better understand their therapeutic potential. Written for both new and established scientists in pharmacology, cell biology, biochemistry, and signal transduction, as well as physicians, this book clearly illustrates how biased receptor signaling can be utilized to develop and understand complex pharmacology. Chapters are each focused on a specific class of receptor or other important topic and make use of real-world examples illustrating how the latest research in signal transduction has led to a better understanding of pharmacology and cell biology. This structure creates a basis for understanding that physiological signalling bias has been selected by nature in order to provide complex and tissue- specific biological responses in the face of limited receptors and signaling pathways. This book provides a framework to reveal that these physiological mechanisms are not restricted to one receptor type or family and thus presents receptor signaling from a newer, more global perspective.

The Biological Action of Physical Medicine

  • 1st Edition
  • May 3, 2014
  • Jan Zbigniew Szopinski
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 8 0 0 0 3 8 - 0
  • eBook
    9 7 8 - 0 - 1 2 - 8 0 0 4 8 4 - 5
The Biological Action of Physical Medicine: Controlling the Human Body's Information System challenges the contemporary way of thinking of diagnostics and therapy "from the outside." Drawing on 30 years of independent comprehensive research, this reference provides a universal and scientifically acceptable physiological theory, explaining the mode of action of methods of physical medicine as well as the underlying physiological mechanisms. Scientific research described in this book explains the universal neurophysiological foundation of all the respective methods, including organ electrodermal diagnostics (OED), thermotherapy (heat, cryostimulation), phototherapy (infrared, ultraviolet, laser), ultrasound therapy, electrotherapy (from transcutaneous electric nerve stimulation to electromagnetic field therapies), magnetotherapy, and mechanical nerve stimulation (acupuncture, reflexive massage, cupping, high-pressure hydrotherapy). A better understanding of physical medicine's modes of action not only insures better clinical results, but also illuminates pain mechanisms and our understanding of the functioning of the nervous system.

A Pharmacology Primer

  • 4th Edition
  • March 26, 2014
  • Terry P. Kenakin
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 4 0 7 6 6 3 - 1
  • eBook
    9 7 8 - 0 - 1 2 - 4 0 7 6 8 9 - 1
A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, 4th Edition features the latest ideas and research about the application of pharmacology to the process of drug discovery to equip readers with a deeper understanding of the complex and rapid changes in this field. Written by well-respected pharmacologist, Terry P. Kenakin, this primer is an indispensable resource for all those involved in drug discovery. This edition has been thoroughly revised to include material on data-driven drug discovery, biased signaling, structure-based drug design, drug activity screening, drug development (including pharmacokinetics and safety Pharmacology), and much more. With more color illustrations, examples, and exercises throughout, this book remains a top reference for all industry and academic scientists and students directly involved in drug discovery, or pharmacologic research.

Side Effects of Drugs Annual

  • 1st Edition
  • Volume 35
  • March 4, 2014
  • Jeffrey K Aronson
  • English
  • Hardback
    9 7 8 - 0 - 4 4 4 - 6 2 6 3 5 - 6
  • eBook
    9 7 8 - 0 - 4 4 4 - 6 2 6 3 6 - 3
The Side Effects of Drugs Annual was first published in 1977. It has been continually published since then as a yearly update to the voluminous encyclopedia, Meyler's Side Effects of Drugs. Each new Annual continues to provide clinicians and medical investigators with a reliable and critical yearly survey of new data and trends in the area of adverse drug reactions and interactions. An international team of specialists has contributed to the informative Annual by critically interpreting it and by pointing to whatever is misleading.

Advances in Immunopharmacology

  • 1st Edition
  • October 22, 2013
  • J. W. Hadden + 1 more
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 2 - 8 6 0 9 - 9
The second of two volumes covering the most recent developments in this new field. Like the previous volume, this book brings together the two fields of immunology and pharmacology, and offers a review format for advances in basic aspects, as well as an update in discussion format of therapy-related advances.

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