Skip to main content
Elsevier
View Cart
openUserAccount

Books in Pharmaceutical science

BooksJournals
61-70 of 95 results in All results

Nonclinical Assessment of Abuse Potential for New Pharmaceuticals

  • 1st Edition
  • July 14, 2015
  • Carrie Markgraf + 2 more
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 4 2 0 1 7 2 - 9
  • eBook
    9 7 8 - 0 - 1 2 - 4 2 0 2 1 6 - 0
Nonclinical Assessment of Abuse Potential for New Pharmaceuticals offers a complete reference on the current international regulatory guidelines and details best practice methodology for the three standard animal models used to evaluate abuse potential: physical dependence, self-administration and drug discrimination. This book also includes chapters on alternative models and examples of when you should use these alternatives. Case histories are provided at the end of the book to show how the data generated from the animal models play a pivitol role in the submission package for a new drug. By incorporating all of this information into one book, Nonclinical Assessment of Abuse Potential for New Pharmaceuticals is your single resource for everything you need to know to understand and implement the assessment of abuse liability.

Profiles of Drug Substances, Excipients and Related Methodology

  • 1st Edition
  • Volume 40
  • May 26, 2015
  • Harry G. Brittain
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 8 0 3 3 0 0 - 5
  • eBook
    9 7 8 - 0 - 1 2 - 8 0 3 3 7 3 - 9
Volumes in this widely revered series present comprehensive reviews of drug substances and additional materials, with critical review chapters that summarize information related to the characterization of drug substances and excipients. This organizational structure meets the needs of the pharmaceutical community and allows for the development of a timely vehicle for publishing review materials on this topic. The scope of the Profiles series encompasses review articles and database compilations that fall within one of the following six broad categories: Physical profiles of drug substances and excipients; Analytical profiles of drug substances and excipients; Drug metabolism and pharmacokinetic profiles of drug substances and excipients; Methodology related to the characterization of drug substances and excipients; Methods of chemical synthesis; and Reviews of the uses and applications for individual drug substances, classes of drug substances, or excipients.

Principles of Translational Science in Medicine

  • 2nd Edition
  • April 2, 2015
  • Martin Wehling
  • English
  • eBook
    9 7 8 - 0 - 1 2 - 8 0 0 7 2 1 - 1
Principles of Translational Science in Medicine: From Bench to Bedside, Second Edition, provides an update on major achievements in the translation of research into medically relevant results and therapeutics. The book presents a thorough discussion of biomarkers, early human trials, and networking models, and includes institutional and industrial support systems. It also covers algorithms that have influenced all major areas of biomedical research in recent years, resulting in an increasing numbers of new chemical/biological entities (NCEs or NBEs) as shown in FDA statistics. The book is ideal for use as a guide for biomedical scientists to establish a systematic approach to translational medicine.

Novel Approaches and Strategies for Biologics, Vaccines and Cancer Therapies

  • 1st Edition
  • December 30, 2014
  • Manmohan Singh + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 4 1 6 6 0 3 - 5
  • eBook
    9 7 8 - 0 - 1 2 - 4 1 6 6 6 1 - 5
Novel Approaches and Strategies for Biologics, Vaccines and Cancer Therapies takes a look at the current strategies, successes and challenges involved with the development of novel formulations of biologics, vaccines and cancer therapy. This thorough reference on the latest trends in the development of diverse modalities will appeal to a broad community of scientists, students and clinicians. Written by leading authors across academia and industry, this book covers important topics such as unique drug delivery devices, non-parenteral delivery trends, novel approaches to the treatment of cancer, immunotherapy and more. It includes real-world cases and examples which highlight formulations with therapeutic proteins, monoclonal antibodies, peptides and biobetters, as well as cases on novel vaccines formulations including evolving pathogens, novel modalities of vaccines, universal vaccines. This book is a thorough and useful resource on the development of novel biologics, vaccines and cancer therapies.

Handbook of Cosmeceutical Excipients and their Safeties

  • 1st Edition
  • September 2, 2014
  • K Y Heng + 5 more
  • English
  • Hardback
    9 7 8 - 1 - 9 0 7 5 6 8 - 5 3 - 4
  • eBook
    9 7 8 - 1 - 9 0 8 8 1 8 - 7 1 - 3
Cosmeceuticals are the latest additions to the health industry and have an ever-expanding market. They are considered to be a marriage between cosmetics and drugs and are defined as preparations applied on the body that may modify the physiological functions of the skin. However, as more cosmeceuticals are being launched in the market and more types of drugs are incorporated into the formulation, the composition of cosmeceuticals is becoming more complex. Handbook of Cosmeceutical Excipients and their Safeties summarises the current evidence relating to cosmeceuticals’ side effects and highlights the important information that practitioners and consumers need to know, as well as ways to avoid the adverse effects of the excipients. Handbook of Cosmeceutical Excipients and their Safeties includes chapters covering topics such as the history of cosmeceuticals and the laws that regulate them, skin permeation, carcinogenicity as a systemic adverse effect and dermatitis as a topical adverse effect. It concludes with an appendix that gives brief information on the potency and permeability of common ingredients in cosmeceuticals. The appendix aims to highlight the maximum allowable quantity of each ingredient to ensure product safety for consumers. The appendix was prepared by compiling the ingredients of 257 products containing more than 500 compounds, collected from a hospital pharmacy in Singapore.

Colloid and Interface Science in Pharmaceutical Research and Development

  • 1st Edition
  • July 18, 2014
  • Hiroyuki Ohshima + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 4 4 4 - 6 2 6 1 4 - 1
  • eBook
    9 7 8 - 0 - 4 4 4 - 6 2 6 0 8 - 0
Colloid and Interface Science in Pharmaceutical Research and Development describes the role of colloid and surface chemistry in the pharmaceutical sciences. It gives a detailed account of colloid theory, and explains physicochemical properties of the colloidal-pharmaceutical systems, and the methods for their measurement. The book starts with fundamentals in Part I, covering fundamental aspects of colloid and interface sciences as applied to pharmaceutical sciences and thus should be suitable for teaching. Parts II and III treat applications and measurements, and they explains the application of these properties and their influence and use for the development of new drugs.

Alkyl Polyglucosides

  • 1st Edition
  • July 4, 2014
  • Ivana Pantelic
  • English
  • Hardback
    9 7 8 - 1 - 9 0 7 5 6 8 - 6 5 - 7
  • eBook
    9 7 8 - 1 - 9 0 8 8 1 8 - 7 7 - 5
The on-going ‘green’ trend in the personal care industry coupled with global environmental concerns, place natural-origin, biodegradable and skin-friendly surfactants such as alkyl polyglucosides (APGs) in high demand. After successful use in cosmetics, sufficient data has been obtained to welcome some sugar emulsifiers into the field of drug dosage. Alkyl Polyglucosides presents a comprehensive compendium which guides a researcher from the APG-related preformulation stages to formulation processing, including the investigation of various APG-stabilized systems skin performance. This book introduces various APG representatives, their benefits in relation to certain conventional surfactants, physicochemical and interfacial properties, possible interaction with commonly used ingredients and diverse characterization techniques indispensable for the assessment of colloidal systems. The first chapter introduces alkyl polyglucosides, followed by chapters on their properties, behaviour, an overview of the patent protection mechanisms and guidelines for submitting patent applications. Finally, a conclusion surveys international patent applications involving APGs.

Profiles of Drug Substances, Excipients and Related Methodology

  • 1st Edition
  • Volume 39
  • May 1, 2014
  • Harry G. Brittain
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 8 0 0 1 7 3 - 8
  • eBook
    9 7 8 - 0 - 1 2 - 8 0 0 4 0 1 - 2
Volumes in this widely revered series present comprehensive reviews of drug substances and additional materials, with critical review chapters that summarize information related to the characterization of drug substances and excipients. This organizational structure meets the needs of the pharmaceutical community and allows for the development of a timely vehicle for publishing review materials on this topic. The scope of the Profiles series encompasses review articles and database compilations that fall within one of the following six broad categories: Physical profiles of drug substances and excipients; Analytical profiles of drug substances and excipients; Drug metabolism and pharmacokinetic profiles of drug substances and excipients; Methodology related to the characterization of drug substances and excipients; Methods of chemical synthesis; and Reviews of the uses and applications for individual drug substances, classes of drug substances, or excipients.

Predictive Modeling of Pharmaceutical Unit Operations

  • 1st Edition
  • April 9, 2014
  • Preetanshu Pandey + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 0 8 - 1 0 0 1 5 4 - 7
  • eBook
    9 7 8 - 0 - 0 8 - 1 0 0 1 8 0 - 6
The use of modeling and simulation tools is rapidly gaining prominence in the pharmaceutical industry covering a wide range of applications. This book focuses on modeling and simulation tools as they pertain to drug product manufacturing processes, although similar principles and tools may apply to many other areas. Modeling tools can improve fundamental process understanding and provide valuable insights into the manufacturing processes, which can result in significant process improvements and cost savings. With FDA mandating the use of Qualityby Design (QbD) principles during manufacturing, reliable modeling techniques can help to alleviate the costs associated with such efforts, and be used to create in silico formulation and process design space. This book is geared toward detailing modeling techniques that are utilized for the various unit operations during drug product manufacturing. By way of examples that include case studies, various modeling principles are explained for the nonexpert end users. A discussion on the role of modeling in quality risk management for manufacturing and application of modeling for continuous manufacturing and biologics is also included.

International Cooperation, Convergence and Harmonization of Pharmaceutical Regulations

  • 1st Edition
  • December 5, 2013
  • Pierre-Louis Lezotre
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 8 0 0 0 5 3 - 3
  • eBook
    9 7 8 - 0 - 1 2 - 8 0 0 5 6 9 - 9
International Cooperation, Convergence and Harmonization of Pharmaceutical Regulations: A Global Perspective provides the current status of the complex and broad phenomenon of cooperation, convergence and harmonization in the pharmaceutical sector (Part I), thoroughly evaluates its added value and its critical parameters and influencing factors (Part II) in order to recommend actions and measures to support the next steps for cooperation, convergence and harmonization (Part III). All of these recommendations in the book support the establishment of a better coordinated global pharmaceutical system which represents the best realistic alternative to fulfill the objective to establish a global coalition of regulators and to respond to an increased demand to further cooperation in the pharmaceutical sector. This proposed framework, which leverages all of the ongoing positive cooperation initiatives and uses as foundations all of the numerous harmonization projects developed over the years, presents advantages for all stakeholders and would definitively have significant added value to the promotion and protection of global public health.