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Books in Infection and immunity

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11-20 of 27 results in All results

Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging

  • 1st Edition
  • December 28, 2016
  • M. A. Hayat
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 8 0 5 4 2 0 - 8
  • eBook
    9 7 8 - 0 - 1 2 - 8 0 9 4 2 7 - 3
Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging is an eleven volume series that discusses in detail all aspects of autophagy machinery in the context of health, cancer, and other pathologies. Autophagy maintains homeostasis during starvation or stress conditions by balancing the synthesis of cellular components and their deregulation by autophagy. This series discusses the characterization of autophagosome-enriched vaccines and its efficacy in cancer immunotherapy. Autophagy serves to maintain healthy cells, tissues, and organs, but also promotes cancer survival and growth of established tumors. Impaired or deregulated autophagy can also contribute to disease pathogenesis. Understanding the importance and necessity of the role of autophagy in health and disease is vital for the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. Comprehensive and forward-thinking, these books offer a valuable guide to cellular processes while also inciting researchers to explore their potentially important connections.

Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging

  • 1st Edition
  • April 8, 2016
  • M. A. Hayat
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 8 0 2 9 3 6 - 7
  • eBook
    9 7 8 - 0 - 1 2 - 8 0 2 9 5 1 - 0
Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging: Volume 9: Human Diseases and Autophagosome offers a valuable guide to both cellular processes while helping researchers explore their potentially important connections. Volume 9 emphasizes the role of autophagy in diseases, such as leukemia, antifungal and antibacterial immunity, and transplantation. This volume also explains, in detail, the molecular mechanism(s) underlying the formation of autophagosomes, including the progression of omegasomes to autophagosomes. This information is important because one of the major functions of autophagy is to degrade and eliminate excessive, old, and harmful materials from the cell. Autophagosomes receive these materials (cellular cargo) and transport them to lysosomes for degradation. Lysosomes contain the digestive enzymes (hydrolases) that breakdown proteins, lipids, carbohydrates, etc. (self-digestion). To further explain this phenomenon, the role of the endoplasmic reticulum (ER) in the formation of autophagosomes is discussed. ULK1 and Beclin 1 proteins are also important in the initial formation of autophagosomes, and are also discussed. Because much of the early research in this area was carried out using yeast cells, the role of Golgi complex in the autophagosome formation in these cells is explained. This volume also includes an explanation of the role of the autophagy-related gene ATG5 in cancer (e.g., gastrointestinal cancer). Paradoxically, autophagy is a “double-edged sword” because it eliminates some pathogens, whereas it can be used by some intracellular pathogens to multiply and cause infection. This book is an asset to newcomers, providing a concise overview of the role of autophagy in necrosis and inflammation, while also serving as an excellent reference for more experienced scientists and clinicians.

Core Concepts in Clinical Infectious Diseases (CCCID)

  • 1st Edition
  • March 15, 2016
  • Carlos Franco-Paredes
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 0 4 4 2 3 - 0
  • eBook
    9 7 8 - 0 - 1 2 - 8 0 4 4 8 0 - 3
Core Concepts in Clinical Infectious Diseases (CCCID) provides medical students and researchers, infectious disease fellows, and practicing clinicians with key clinical concepts in the differential diagnosis and workup of infectious diseases. With the use of tables, charts, and problem-oriented medical diagnosis, it will provide a way of organizing and thinking about commonly seen clinical presentations of infectious diseases. Instead of discussing each disease process or any particular infectious process, this book will assist clinicians in seeing the forest and not focusing on the leaf. Graphs and tables have been constructed over 14 years of taking notes, teaching clinical infectious diseases, and discussing real clinical cases. This book is not about acquiring the structure of infectious diseases that is presented in classic textbooks of infectious disease; instead, it is about refining the process of putting the pieces together in clinical thinking to achieve an accurate clinical diagnosis and thus improved patient care.

Amphioxus Immunity

  • 1st Edition
  • December 7, 2015
  • An-Long Xu
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 8 4 9 9 0 3 - 0
  • eBook
    9 7 8 - 0 - 1 2 - 8 0 9 6 4 7 - 5
Amphioxus Immunity: Tracing the Origin of Human Immunity covers a remarkable range of information about Amphioxus and its evolutionary context. This compilation of what is currently known about Amphioxus, with a sharp focus on its immune system, includes 13 topics, such as: Amphioxus as a model for understanding the evolution of vertebrates basic knowledge of immunology immune organs and cells of amphioxus a genomic and transcriptomic view of the Amphioxus immunity pattern recognition system in Amphioxus transcription factors in Amphioxus the complement system of Amphioxus the oxidative burst system in Amphioxus immune effectors in Amphioxus lipid signaling of immune response in Amphioxus apoptosis in amphioxus; primitive adaptive immune system of Amphioxus and future research directions This valuable reference book is loaded with information that will be useful for anyone who wishes to learn more about the origin of vertebrates and adaptive immunity.

Allergy, Immunity and Tolerance in Early Childhood

  • 1st Edition
  • September 10, 2015
  • Hans Ulrich Wahn + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 4 2 0 2 2 6 - 9
  • eBook
    9 7 8 - 0 - 1 2 - 7 9 9 9 3 0 - 2
Allergy, Immunity and Tolerance in Early Childhood: The First Steps of the Atopic March provides valuable insights on the atopic diseases, including asthma, allergic rhinitis, atopic dermatitis, and food allergies, which have developed into major health problems in most parts of the world. As the natural history of these chronic diseases has been extensively studied, including their major genetic, environmental, and lifestyle determinants and potential protective factors, the book presents tactics on how pediatric allergists can provide early intervention. In addition, the book unites key, global experts in the field who summarize their collective, and current, knowledge of the early stage of the "Atopic March", along with novel ideas for potential options of prevention.

Infection and Autoimmunity

  • 2nd Edition
  • January 22, 2015
  • Yehuda Shoenfeld + 2 more
  • English
  • Paperback
    9 7 8 - 0 - 4 4 4 - 6 3 2 6 9 - 2
  • eBook
    9 7 8 - 0 - 4 4 4 - 6 3 2 7 2 - 2
Autoimmune diseases are conditions where the immune system attacks the body organs instead of foreign invaders. This book deals with the various mechanisms by which infectious agents can trigger autoimmunity such as molecular mimicry and polyclonal activation. An overview is given with regard to bacteria, viruses, and parasites associated with autoimmunity, and a summary is given on classical autoimmune diseases and the infecting agents that can induce them.

Primer to the Immune Response

  • 2nd Edition
  • December 23, 2013
  • Tak W. Mak + 2 more
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 3 8 5 2 4 5 - 8
  • eBook
    9 7 8 - 0 - 1 2 - 3 8 5 4 6 1 - 2
Written in the same engaging conversational style as the acclaimed first edition, Primer to The Immune Response, 2nd Edition is a fully updated and invaluable resource for college and university students in life sciences, medicine and other health professions who need a concise but comprehensive introduction to immunology. The authors bring clarity and readability to their audience, offering a complete survey of the most fundamental concepts in basic and clinical immunology while conveying the subject’s fascinating appeal. The content of this new edition has been completely updated to include current information on all aspects of basic and clinical immunology. The superbly drawn figures are now in full color, complemented by full color plates throughout the book. The text is further enhanced by the inclusion of numerous tables, special topic boxes and brief notes that provide interesting insights. At the end of each chapter, a self-test quiz allows students to monitor their mastery of major concepts, while a set of conceptual questions prompts them to extrapolate further and extend their critical thinking. Moreover, as part of the Academic Cell line of textbooks, Primer to The Immune Response, 2nd Edition contains research passages that shine a spotlight on current experimental work reported in Cell Press articles. These articles also form the basis of case studies that are found in the associated online study guide and are designed to reinforce clinical connections.

Diet, Immunity and Inflammation

  • 1st Edition
  • September 30, 2013
  • Philip C Calder + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 0 8 - 1 0 1 3 8 0 - 9
  • eBook
    9 7 8 - 0 - 8 5 7 0 9 - 5 7 4 - 9
Although inflammation is one of the body’s first responses to infection, overactive immune responses can cause chronic inflammatory diseases. Long-term low-grade inflammation has also been identified as a risk factor for other diseases. Diet, immunity and inflammation provides a comprehensive introduction to immunity and inflammation and the role that diet and nutrition play with regard to this key bodily response.Part one, an introductory section, discusses innate and adaptive immunity, mucosal immunity in a healthy gut and chronic inflammatory diseases and low grade inflammation. Chapters in part two highlight the role of micronutrients, including zinc, selenium, iron, vitamin A and vitamin D, in inflammation and immunity. Part three explores other dietary constituents and includes chapters on intestinal bacteria and probiotics, the impacts of prebiotics on the immune system and inflammation, and antimicrobial, immunomodulatory and anti-inflammatory effects of food bioactive proteins and peptides. Further chapters explore the role of olive oil, short and long chain fatty acids and arginine and glutamine in immune functions. Nutrition, immunity and inflammation are discussed from an integrative and life course perspective in part four. Chapters focus on adverse immune reactions to foods, early nutritional programming, the impact of nutrition on the immune system during ageing, the impact of exercise on immunity and the interaction with nutrition, and the effect that malnutrition has on immunity and susceptibility to infection.With its distinguished editors and international team of expert contributors, Diet, immunity and inflammation is a comprehensive resource for those researching immunology or inflammation, nutrition scientists, and professionals in the food and nutrition industries who require an understanding of the effect that diet can have on the immune system and inflammation.

Developmental Aspects of Carcinogenesis and Immunity

  • 1st Edition
  • September 24, 2013
  • Thomas J. King
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 2 - 6 2 1 2 - 3
Developmental Aspects of Carcinogenesis and Immunity presents the proceedings of the 32nd symposium of the Society for Developmental Biology, held at Kansas State University, Manhattan, Kansas in June 1973. The meeting aims to highlight the advances in carcinogenesis and immunity and emphasize their relationship to fundamental processes of developmental biology. Leading investigators present their studies on various aspects of the two fields such as mechanisms underlying tumor transformation; cell proliferation, differentiation, and neoplasia; transformation of cells in culture; and role of embryonic and fetal antigens in cancer, lymphocyte differentiation, cell-mediated destruction of tumor cells, and the enhancement of the effects of antibodies through the process of immune surveillance. Oncologists, cell biologists, medical researchers, physiologists, molecular biologists, physicians, and students in the field of medicine will find the book insightful.

Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging

  • 1st Edition
  • September 3, 2013
  • M. A. Hayat
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 4 0 5 8 7 7 - 4
  • eBook
    9 7 8 - 0 - 1 2 - 4 1 1 5 1 4 - 9
Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging is a complete, authoritative examination of the role of autophagy in health and disease. Understanding this phenomenon is vital for the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. Comprehensive and forward thinking, this four-volume work offers a valuable guide to cellular processes while encouraging researchers to explore their potentially important connections. Understanding the role of autophagy is critical, considering its association with numerous biological processes, including cellular development and differentiation, cancer (both antitumor and protumor functions), immunity, infectious diseases, inflammation, maintenance of homeostasis, response to cellular stress, and degenerative diseases such as Alzheimer's, Parkinson's, Huntington's, amyotrophic lateral sclerosis, and prion diseases. Cell homeostasis is achieved by balancing biosynthesis and cellular turnover. In spite of the increasing importance of autophagy in various pathophysiological conditions mentioned above, this process remains underestimated and overlooked. As a consequence, its role in the initiation, stability, maintenance, and progression of these and other diseases (e.g., autoimmune disease) remains poorly understood. This work will broaden the knowledge base of academic and clinical professors, post-doctoral fellows, graduate and medical students regarding this vital biological process. Volumes in the Series Volume 1: Molecular Mechanisms. Elucidates autophagy’s association with numerous biological processes, including cellular development and differentiation, cancer, immunity, infectious diseases, inflammation, maintenance of homeostasis, response to cellular stress, and degenerative diseases such as Alzheimer’s, Parkinson's, Huntington's, amyotrophic lateral sclerosis, and prion diseases. Volume 2: Role in General Diseases. Describes the various aspects of the complex process of autophagy in a myriad of devastating human diseases, expanding from a discussion of essential autophagic functions into the role of autophagy in proteins, pathogens, immunity, and general diseases. Volume 3: Role in Specific Diseases. Explores the role of autophagy in specific diseases and developments, including: Crohn’s Disease, Gaucher Disease, Huntington’s Disease, HCV infection, osteoarthritis, and liver injury, with a full section devoted to in-depth exploration of autophagy in tumor development and cancer, as well as the relationship between autophagy and apoptosis.Volume 4: Mitophagy. Presents detailed information on the role of mitophagy, the selective autophagy of mitochondria, in health and disease, by delivering an in-depth treatment of the molecular mechanisms involved in mitophagy initiation and execution, as well as the role of mitophagy in Parkinson Disease, cardiac aging, and skeletal muscle atrophy. Volume 5: Role in Human Diseases. Comprehensively describes the role of autophagy in human diseases, delivering coverage of the antitumor and protumor roles of autophagy; the therapeutic inhibition of autophagy in cancer; and the duality of autophagy’s effects in various cardiovascular, metabolic, and neurodegenerative disorders.Volume 6: Regulation of Autophagy and Selective Autophagy. Provides coverage of the mechanisms of regulation of autophagy; intracellular pathogen use of the autophagy mechanism; the role of autophagy in host immunity; and selective autophagy. Volume 7: Role of Autophagy in Therapeutic Applications. Provides coverage of the latest developments in autophagosome biogenesis and regulation; the role of autophagy in protein quality control; the role of autophagy in apoptosis; autophagy in the cardiovascular system; and the relationships between autophagy and lifestyle. Volume 8: Autophagy and Human Diseases. Reviews recent advancements in the molecular mechanisms underlying a large number of genetic and epigenetic diseases and abnormalities, and introduces new, more effective therapeutic strategies, in the development of targeted drugs and programmed cell death, providing information that will aid on preventing detrimental inflammation.Volume 9: Necrosis and Inflammation in Human Diseases. Emphasizes the role of Autophagy in necrosis and inflammation, explaining in detail the molecular mechanism(s) underlying the formation of autophagosomes, including the progression of Omegasomes to autophagosomes.