Books in Autoimmunity

The Value of BCG and TNF in Autoimmunity

1st Edition
March 13, 2014
Denise Faustman
English
eBook
9 7 8 0 1 2 8 0 0 4 6 1 6

The Value of BCG and TNF in Autoimmunity provides an overview of current research and thinking related to tumor necrosis factor (TNF) induction and the use of the bacillus Calmette-Guérin (BCG) vaccine as potential treatment approaches to diverse forms of autoimmunity. BCG, commonly known as an anti-tuberculosis vaccine, is being explored in worldwide clinical trials as an approach to the treatment of certain forms of autoimmunity. The scope of research behind this therapeutic approach spans from the basic science of TNF signaling to research in diverse autoimmune disciplines, such as type 1 diabetes and multiple sclerosis. Overall, the book focuses on the lessons that can be learned from the researchers' individual experiences and data, and provides a rationale for bringing the inexpensive, generic BCG vaccine to the forefront of clinical trials in different forms of autoimmunity.

Autoantibodies

3rd Edition
November 26, 2013
Yehuda Shoenfeld + 2 more
English
Hardback
9 7 8 0 4 4 4 5 6 3 7 8 1
eBook
9 7 8 0 4 4 4 5 9 3 7 7 1

Autoimmune diseases are characterized by the occurrence of antibodies reacting with self-constituents of the body. The fully updated third edition of Autoantibodies is an in-depth review of the main autoantibodies identified up to now, with particular emphasis on those that display a diagnostic or prognostic clinical value. The new edition covers recent scientific advances, diagnostic techniques, and therapeutic technologies. Each chapter is focused on a single family of autoantibodies. This important reference contains historical notes, definitions, origins and sources of antigens recognized genetic associations, mediated pathogenic mechanisms, methods of detection, as well as clinical utility (disease prevalence and association, diagnostic value, sensitivity and specificity, prognostic value). This is an ideal reference for anyone involved in the field of autoimmune diseases.

The Autoimmune Diseases II

1st Edition
December 2, 2012
M. Eric Gershwin + 1 more
English
eBook
9 7 8 0 3 2 3 1 4 0 3 3 1

This book deals with autoimmune disease in humans (as opposed to autoimmunity itself). It discusses the biological basis of disease at the molecular, genetic, cellular, and epidemiologic levels. It also describes the clinical problems of diagnosis, prognosis, and treatment. The intended audience includes physicians of all specialties in practice, physicians in training such as house staff and fellows, and medical students. It will also be valuable for basic scientists and graduate students interested in the solution of important clinical problems. The book concentrates on topics that have grown or changed dramatically since publication of The Autoimmune Diseases.

Systemic Lupus Erythematosus

5th Edition
October 29, 2010
Robert G. Lahita + 3 more
English
eBook
9 7 8 0 0 8 0 9 6 1 7 1 2

Systemic lupus erythematosus (S.L.E.), commonly called lupus, is a chronic autoimmune disorder that can affect virtually any organ of the body. In lupus, the body's immune system, which normally functions to protect against foreign invaders, becomes hyperactive, forming antibodies that attack normal tissues and organs, including the skin, joints, kidneys, brain, heart, lungs, and blood. Lupus is characterized by periods of illness, called flares, and periods of wellness, or remission. Because its symptoms come and go and mimic those of other diseases, lupus is difficult to diagnose. There is no single laboratory test that can definitively prove that a person has the complex illness. To date, lupus has no known cause or cure. Early detection and treatment is the key to a better health outcome and can usually lessen the progression and severity of the disease. Anti-inflammatory drugs, anti-malarials, and steroids (such as cortisone and others) are often used to treat lupus. Cytotoxic chemotherapies, similar to those used in the treatment of cancer, are also used to suppress the immune system in lupus patients. A new edition of this established and well regarded reference which combines basic science with clinical science to provide a translational medicine model. Systemic Lupus Erythematosus is a useful reference for specialists in the diagnosis and management of patients with SLE, a tool for measurement of clinical activity for pharmaceutical development and basic research of the disease and a reference work for hospital libraries.

Systemic Lupus Erythematosus

5th Edition
October 29, 2010
Robert G. Lahita + 3 more
English
eBook
9 7 8 0 0 8 0 9 6 1 7 1 2

Antiphospholipid Syndrome in Systemic Autoimmune Diseases

1st Edition
Volume 12
April 1, 2009
R. Cervera + 2 more
English
eBook
9 7 8 0 0 8 0 9 3 2 3 4 7

Antiphospholipid syndrome is an autoimmune disease that causes abnormal blood clots. It is now recognized as a major cause of common conditions, including stroke, heart attack, miscarriage, epilepsy and memory loss and as such is gaining recognition in all branches of medicine, from obstetrics to cardiology, from psychiatry to orthopedics.This book provides an overview of our current understanding of this major disease. It includes the latest information on the new pathogenetic mechanisms involved as well as clinical manifestations in both “the thrombotic” and “non-thrombotic” manifestations of this important disease.

Endocrine Manifestations of Systemic Autoimmune Diseases

1st Edition
Volume 9
May 12, 2008
Ronald Asherson + 2 more
English
Hardback
9 7 8 0 4 4 4 5 3 1 7 2 8
eBook
9 7 8 0 0 8 0 5 5 9 3 2 2

This book is one of the first to evaluate the role of Steroids in autoimmune rheumatic diseases from the basic mechanisms to the clinical involvements and focuses on the importance of steroidal hormones in the pathogenesis and therapeutic management of the autoimmune rheumatic diseases. In particular, the chapters analyze the mechanisms of action and the involvement of adrenal steroids (glucocorticoids) in the neuroendocrine immune system, including effects on the elderly. The perturbations of the HPA axis as a source of altered steroidal synthesis will be discussed and related to some interesting pathological conditions that commonly complicate the autoimmune rheumatic diseases such as psychosis or fibromyalgia. Concerning the role of gonadal steroids (sex hormones), several chapters will discuss clinical and epidemiological evidences of their role, as well as their effects as risk factors in autoimmune rheumatic diseases, including a section on pediatrics.

Primer to The Immune Response

1st Edition
April 22, 2008
Tak W. Mak + 2 more
English
eBook
9 7 8 0 0 8 0 5 6 9 6 5 9

Primer to The Immune Response is an invaluable resource for college students, university undergraduates and students in medicine and other health professions who need a concise but complete and understandable introduction to immunology. This book is written in the same engaging conversational style as the published reference book The Immune Response: Basic and Clinical Principles and conveys the same fascinating appeal of immunology. The authors bring clarity, readability and continuity of voice to an audience that requires only a brief survey of the most fundamental concepts in basic and clinical immunology. Primer to The Immune Response is beautifully illustrated with over 200 superb figures and 36 full-color plates, and further enhanced by the inclusion of 60 tables and 6 Appendices. Included with purchase of the book is website access to a captivating “Immunomovie" that truly brings the immune response to pathogens to life. This new and unique immunology textbook compactly but elegantly covers both basic and clinical principles.

Digestive Involvement in Systemic Autoimmune Diseases

1st Edition
Volume 13
March 6, 2008
Manel Ramos-Casals + 4 more
English
eBook
9 7 8 0 0 8 0 5 5 9 3 1 5

The Digestive System in Systemic Autoimmune Diseases represents the state-of-the-art in the field of digestive disorders in the most common systemic autoimmune diseases.The volume consists of an introductory chapter on imaging techniques in digestive diseases, followed by eight chapters on digestive manifestations in specific systemic autoimmune diseases. The final five chapters deal with digestive diseases with an autoimmune pathogenesis and systemic manifestations.Inter... in scope, the table of contents reads like a Who's who in clinical research on systemic autoimmune diseases. More than 20 contributors from the European Union, the United States, Mexico and South Africa share their knowledge in this detailed volume.

The Kidney in Systemic Autoimmune Diseases

1st Edition
Volume 7
December 14, 2007
Justin C Mason + 2 more
English
Hardback
9 7 8 0 4 4 4 5 2 9 7 2 5
eBook
9 7 8 0 0 8 0 5 5 7 0 4 5

This volume brings together an international group of clinicians and clinical scientists to contribute to a state-of the-art review of the underlying pathogenic mechanisms, methods of clinical assessment, classification and diagnosis of renal disease, combined with a detailed overview of treatment strategies. An essential reference source for all those involved with the care of patients with renal involvement in systemic autoimmune disease, and for those contributing to research into the underlying pathogenic mechanisms in these disorders.

Life Sciences

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Social Sciences & Humanities

Health

Books in Autoimmunity

The Value of BCG and TNF in Autoimmunity

Autoantibodies

The Autoimmune Diseases II

Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

Antiphospholipid Syndrome in Systemic Autoimmune Diseases

Endocrine Manifestations of Systemic Autoimmune Diseases

Primer to The Immune Response

Digestive Involvement in Systemic Autoimmune Diseases

The Kidney in Systemic Autoimmune Diseases