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Books in Autoimmunity

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21-30 of 42 results in All results

Systemic Lupus Erythematosus

  • 1st Edition
  • December 23, 2015
  • George C. Tsokos
  • English
  • eBook
    9 7 8 - 0 - 1 2 - 8 0 2 0 0 9 - 8
Systemic Lupus Erythematosus combines basic science with clinical science to provide a translational treatment of the disease and is a useful reference for specialists in the diagnosis and management of patients with SLE, a tool for measurement of clinical activity for pharmaceutical development and basic research of the disease and a reference work for hospital libraries.

Infection and Autoimmunity

  • 2nd Edition
  • January 22, 2015
  • Yehuda Shoenfeld + 2 more
  • English
  • Paperback
    9 7 8 - 0 - 4 4 4 - 6 3 2 6 9 - 2
  • eBook
    9 7 8 - 0 - 4 4 4 - 6 3 2 7 2 - 2
Autoimmune diseases are conditions where the immune system attacks the body organs instead of foreign invaders. This book deals with the various mechanisms by which infectious agents can trigger autoimmunity such as molecular mimicry and polyclonal activation. An overview is given with regard to bacteria, viruses, and parasites associated with autoimmunity, and a summary is given on classical autoimmune diseases and the infecting agents that can induce them.

The Value of BCG and TNF in Autoimmunity

  • 1st Edition
  • March 13, 2014
  • Denise Faustman
  • English
  • eBook
    9 7 8 - 0 - 1 2 - 8 0 0 4 6 1 - 6
The Value of BCG and TNF  in Autoimmunity provides an overview of current research and thinking related to tumor necrosis factor (TNF) induction and the use of the bacillus Calmette-Guérin (BCG) vaccine as potential treatment approaches to diverse forms of autoimmunity. BCG, commonly known as an anti-tuberculosis vaccine, is being explored in worldwide clinical trials as an approach to the treatment of certain forms of autoimmunity. The scope of research behind this therapeutic approach spans from the basic science of TNF signaling to research in diverse autoimmune disciplines, such as type 1 diabetes and multiple sclerosis. Overall, the book focuses on the lessons that can be learned from the researchers' individual experiences and data, and provides a rationale for bringing the inexpensive, generic BCG vaccine to the forefront of clinical trials in different forms of autoimmunity.

The Autoimmune Diseases

  • 5th Edition
  • December 3, 2013
  • M. Eric Gershwin + 1 more
  • English
  • eBook
    9 7 8 - 0 - 1 2 - 3 8 4 9 3 0 - 4
Since publication of the 4th Edition of The Autoimmune Diseases in 2006, the understanding of the immune mechanisms underlying autoimmunity and autoimmune disease has significantly deepened and broadened. This fully revised 5th Edition incorporates new material and combines common themes underlying inductive and effector mechanisms and therapies that relate generally to the autoimmune disorders. It discusses the biological basis of disease at genetic, molecular, cellular, and epidemiologic levels and includes expanded coverage of autoinflammatory disease and autoimmune responses to tumors.

Autoantibodies

  • 3rd Edition
  • November 26, 2013
  • Yehuda Shoenfeld + 2 more
  • English
  • Hardback
    9 7 8 - 0 - 4 4 4 - 5 6 3 7 8 - 1
  • eBook
    9 7 8 - 0 - 4 4 4 - 5 9 3 7 7 - 1
Autoimmune diseases are characterized by the occurrence of antibodies reacting with self-constituents of the body. The fully updated third edition of Autoantibodies is an in-depth review of the main autoantibodies identified up to now, with particular emphasis on those that display a diagnostic or prognostic clinical value. The new edition covers recent scientific advances, diagnostic techniques, and therapeutic technologies. Each chapter is focused on a single family of autoantibodies. This important reference contains historical notes, definitions, origins and sources of antigens recognized genetic associations, mediated pathogenic mechanisms, methods of detection, as well as clinical utility (disease prevalence and association, diagnostic value, sensitivity and specificity, prognostic value). This is an ideal reference for anyone involved in the field of autoimmune diseases.

The Autoimmune Diseases II

  • 1st Edition
  • December 2, 2012
  • M. Eric Gershwin + 1 more
  • English
  • eBook
    9 7 8 - 0 - 3 2 3 - 1 4 0 3 3 - 1
This book deals with autoimmune disease in humans (as opposed to autoimmunity itself). It discusses the biological basis of disease at the molecular, genetic, cellular, and epidemiologic levels. It also describes the clinical problems of diagnosis, prognosis, and treatment. The intended audience includes physicians of all specialties in practice, physicians in training such as house staff and fellows, and medical students. It will also be valuable for basic scientists and graduate students interested in the solution of important clinical problems. The book concentrates on topics that have grown or changed dramatically since publication of The Autoimmune Diseases.

Systemic Lupus Erythematosus

  • 5th Edition
  • October 29, 2010
  • Robert G. Lahita + 3 more
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 9 6 1 7 1 - 2
Systemic lupus erythematosus (S.L.E.), commonly called lupus, is a chronic autoimmune disorder that can affect virtually any organ of the body. In lupus, the body's immune system, which normally functions to protect against foreign invaders, becomes hyperactive, forming antibodies that attack normal tissues and organs, including the skin, joints, kidneys, brain, heart, lungs, and blood. Lupus is characterized by periods of illness, called flares, and periods of wellness, or remission. Because its symptoms come and go and mimic those of other diseases, lupus is difficult to diagnose. There is no single laboratory test that can definitively prove that a person has the complex illness. To date, lupus has no known cause or cure. Early detection and treatment is the key to a better health outcome and can usually lessen the progression and severity of the disease. Anti-inflammatory drugs, anti-malarials, and steroids (such as cortisone and others) are often used to treat lupus. Cytotoxic chemotherapies, similar to those used in the treatment of cancer, are also used to suppress the immune system in lupus patients. A new edition of this established and well regarded reference which combines basic science with clinical science to provide a translational medicine model. Systemic Lupus Erythematosus is a useful reference for specialists in the diagnosis and management of patients with SLE, a tool for measurement of clinical activity for pharmaceutical development and basic research of the disease and a reference work for hospital libraries.

Antiphospholipid Syndrome in Systemic Autoimmune Diseases

  • 1st Edition
  • Volume 12
  • April 1, 2009
  • R. Cervera + 2 more
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 9 3 2 3 4 - 7
Antiphospholipid syndrome is an autoimmune disease that causes abnormal blood clots. It is now recognized as a major cause of common conditions, including stroke, heart attack, miscarriage, epilepsy and memory loss and as such is gaining recognition in all branches of medicine, from obstetrics to cardiology, from psychiatry to orthopedics.This book provides an overview of our current understanding of this major disease. It includes the latest information on the new pathogenetic mechanisms involved as well as clinical manifestations in both “the thrombotic” and “non-thrombotic” manifestations of this important disease.

Endocrine Manifestations of Systemic Autoimmune Diseases

  • 1st Edition
  • Volume 9
  • May 12, 2008
  • Ronald Asherson + 2 more
  • English
  • Hardback
    9 7 8 - 0 - 4 4 4 - 5 3 1 7 2 - 8
  • eBook
    9 7 8 - 0 - 0 8 - 0 5 5 9 3 2 - 2
This book is one of the first to evaluate the role of Steroids in autoimmune rheumatic diseases from the basic mechanisms to the clinical involvements and focuses on the importance of steroidal hormones in the pathogenesis and therapeutic management of the autoimmune rheumatic diseases. In particular, the chapters analyze the mechanisms of action and the involvement of adrenal steroids (glucocorticoids) in the neuroendocrine immune system, including effects on the elderly. The perturbations of the HPA axis as a source of altered steroidal synthesis will be discussed and related to some interesting pathological conditions that commonly complicate the autoimmune rheumatic diseases such as psychosis or fibromyalgia. Concerning the role of gonadal steroids (sex hormones), several chapters will discuss clinical and epidemiological evidences of their role, as well as their effects as risk factors in autoimmune rheumatic diseases, including a section on pediatrics.

Primer to The Immune Response

  • 1st Edition
  • April 22, 2008
  • Tak W. Mak + 2 more
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 5 6 9 6 5 - 9
Primer to The Immune Response is an invaluable resource for college students, university undergraduates and students in medicine and other health professions who need a concise but complete and understandable introduction to immunology. This book is written in the same engaging conversational style as the published reference book The Immune Response: Basic and Clinical Principles and conveys the same fascinating appeal of immunology. The authors bring clarity, readability and continuity of voice to an audience that requires only a brief survey of the most fundamental concepts in basic and clinical immunology. Primer to The Immune Response is beautifully illustrated with over 200 superb figures and 36 full-color plates, and further enhanced by the inclusion of 60 tables and 6 Appendices. Included with purchase of the book is website access to a captivating “Immunomovie"” that truly brings the immune response to pathogens to life. This new and unique immunology textbook compactly but elegantly covers both basic and clinical principles.