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Studies in Natural Products Chemistry
- 1st Edition, Volume 68 - February 4, 2021
- Editor: Atta-ur Rahman
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 8 1 9 4 8 5 - 0
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 1 9 4 8 6 - 7
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 8 9 8 0 7 - 2
Studies in Natural Products Chemistry, Volume 68, covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting-edge accounts… Read more
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Request a sales quoteStudies in Natural Products Chemistry, Volume 68, covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting-edge accounts surrounding developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products and their exciting developments in phytochemistry. As natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects, their uses in new drug developments in the pharmaceutical industry has become increasingly important.
With rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, the ability to rapidly isolate and determine the structures and biological activity of natural products has created opportunities for future drug therapies and uses.
- Focuses on the chemistry and phytochemistry applications of bioactive natural products
- Contains contributions by leading authorities in the field of natural products chemistry
- Presents sources of new pharmacophores and pharmacognosy
Natural product chemists, medicinal chemists, pharmacologists as well as academic and industry researchers
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Preface
- Chapter 1: Studies of pentacyclic triterpenoids structures and antidiabetic properties of Myrianthus genus
- Abstract
- Introduction
- Biosynthesis of triterpenoids
- Structures of triterpenes isolated from M. arboreus
- Extraction and isolation of triterpenoids
- Structural elucidation of triterpenoids by spectroscopic methods
- Antidiabetic activities of M. arboreus
- Concluding remark
- Chapter 2: Limonoids and other secondary metabolites of Azadirachta indica (neem) and Azadirachta indica var. siamensis (Siamese neem), and their bioactivities
- Abstract
- Introduction
- Materials and methods
- Limonoids and other secondary metabolites of Azadirachta indica (AI) and Azadiracta indica var. siamensis (AIS)
- Structural features of limonoids and other secondary metabolites of Azadirachta indica (AI) and Azadiracta indica var. siamensis (AIS)
- Bioactivities of limonoids and other secondary metabolites of Azadirachta indica (AI) and Azadiracta indica var. siamensis (AIS)
- Conclusions
- Chapter 3: Steroidal sapogenins from genus Trillium: Chemistry, synthesis, and opportunities in neuro-active steroids designing
- Abstract
- Introduction
- Steroidal saponins from Trillium genus
- Biosynthesis of steroidal saponins
- Functions of steroidal saponins
- Virtual screening of sapogenin with GABAA receptor
- Experimental
- Conclusion
- Chapter 4: Biological activity and 13C NMR spectral data of skeleton type C20 quassinoids (1985–2019)
- Abstract
- Introduction
- Description and 13C NMR data of C20 skeletal-type quassinoids
- Biological activities
- Concluding remarks
- Aknowledgments
- Chapter 5: Carotenoid isomers: A systematic review of the analysis, biological activity, physicochemical property, and methods for isomerization
- Abstract
- Introduction
- General procedure for the analysis of carotenoid isomers
- Effect of E/Z-isomerization on bioavailability and biological activity of carotenoids
- Effect of E/Z-isomerization on physicochemical properties of carotenoids
- Methods for E/Z-isomerization of carotenoids
- Utilization of carotenoid Z-isomerization technique: Future directions
- Chapter 6: Methods, characteristics, variance, and genetics of pine oleoresin components, and their potential for renewable and sustainable energy
- Abstract
- Introduction
- The composition of pine oleoresin
- The genetics of composition of pine oleoresin
- The potential for renewable and sustainable energy
- Chapter 7: Biologically active compounds from Lamiaceae family: Central nervous system effects
- Abstract
- Introduction
- Ethnomedicine
- Lamiaceae family
- Bioactivities of extracts from Lamiaceae species on CNS
- Lamiaceae compounds with CNS activity
- Concluding remarks
- Chapter 8: The chemical constituents and biological activities of Cnidoscolus chayamansa McVaugh, a Mexican medicinal species, and plant cell cultures for the production of bioactive secondary metabolites
- Abstract
- Introduction
- Chapter 9: Developments in extraction, purification, and structural elucidation of proanthocyanidins (2000–2019)
- Abstract
- Introduction
- Extraction of free proanthocyanidins
- Extraction of bound proanthocyanidins
- Purification of proanthocyanidins
- Structural identification of proanthocyanidins
- Concluding remarks
- Acknowledgments
- Chapter 10: A review on xanthone derivatives with antiinflammatory effects and their structure–activity relationship
- Abstract
- Introduction
- Antiinflammatory assay
- Xanthones with antiinflammatory activity
- Conclusion and future perspectives
- Acknowledgment
- Chapter 11: Biotransformation in the production of secondary metabolites
- Abstract
- Introduction
- Secondary metabolites
- Plant metabolic pathways
- Techniques for increasing the secondary metabolites
- Optimization conditions of the biotransformation reactions
- The chemistry techniques used to separate and identify secondary metabolites
- Conclusions
- Chapter 12: The role of natural and nature-based compounds against Chikungunya and Mayaro alphaviruses and their vectors
- Abstract
- Introduction
- Chikungunya virus (CHIKV)
- Mayaro virus (MAYV)
- Medicinal chemistry of CHIKV and MAYV
- Final considerations
- Index
- No. of pages: 524
- Language: English
- Edition: 1
- Volume: 68
- Published: February 4, 2021
- Imprint: Elsevier
- Hardback ISBN: 9780128194850
- eBook ISBN: 9780128194867
- eBook ISBN: 9780323898072
AR
Atta-ur Rahman
Atta-ur-Rahman, Professor Emeritus, International Center for Chemical and Biological Sciences (H. E. J. Research Institute of Chemistry and Dr. Panjwani Center for Molecular Medicine and Drug Research), University of Karachi, Pakistan, was the Pakistan Federal Minister for Science and Technology (2000-2002), Federal Minister of Education (2002), and Chairman of the Higher Education Commission with the status of a Federal Minister from 2002-2008. He is a Fellow of the Royal Society of London (FRS) and an UNESCO Science Laureate. He is a leading scientist with more than 1283 publications in several fields of organic chemistry.
Affiliations and expertise
Professor Emeritus, International Center for Chemical and Biological Sciences (H. E. J. Research Institute of Chemistry and Dr. Panjwani Center for Molecular Medicine and Drug Research), University of Karachi, Pakistan