Structural Studies on Nucleic acids and Other Biopolymers
- 1st Edition - January 1, 1973
- Latest edition
- Editor: J Duchesne
- Language: English
Physico-chemical Properties of Nucleic Acids, Volume II basically deals with the structural studies on nucleic acids and other biopolymers. This volume gives much emphasis on… Read more
Physico-chemical Properties of Nucleic Acids, Volume II basically deals with the structural studies on nucleic acids and other biopolymers. This volume gives much emphasis on conformational changes using spectroscopic techniques and also on methods of thermodynamics and hydrodynamics. Volume II begins with Chapter 10 as continuation of Volume I and discusses the infrared and Raman spectroscopy of nucleic acids and polynucleotides. Chapter 11 delves further into the topic of infrared and Raman spectra particularly the vibrations in the base-residues. This volume also highlights the topic of RNA, where the structure of viral RNA and nuclear magnetic resonance studies of transfer RNAs in solution are covered. The last two chapters discuss the concept of thermodynamic and hydrodynamic properties of conformation transitions and changes. This volume caters to both students and researchers in various fields of science, such as biology, chemistry, molecular biology, biophysics, and microbiology.
Contributors
Preface
Foreword
Contents Vol. 1
Contents Vol. 3
10. Structural Studies of Nucleic Acid and Polynucleotides by Infrared and Raman Spectroscopy
I. Introduction
II. Infrared Studies of Nucleic Acid Structure
III. Raman Spectroscopy and Nucleic Acid Structure
References
11. Infrared and Raman Spectra of Nucleic Acids—Vibrations in the Base Residues
I. Introduction
II. The Spectra of the Four-Base Residues
III. Data for Characterizing Raman Lines and Infrared Absorption Bands
IV. Normal Coordinate Treatment
V. Characterization of each Raman line or Infrared Band
VI. Effects of Inter-Base Interactions
Acknowledgments
References
12. Conformation of Nucleic Acids, Oligo- and Polynucleotides by Circular Dichroism Investigations
I. Introduction
II. Mononucleosides
III. Analysis of Polynucleotide CD
IV. Nucleic Acids
References
13. Nuclear Magnetic Resonance Studies of Transfer RNAs in Solution
I. Introduction
II. The Interaction of Purine with E. coli tRNAfMet
III. Organic Solvent Denaturation of Transfer RNA
IV. Summary
Acknowledgments
References
14. The Structure of Viral RNA
I. Viral RNA Genomes
II. Chemical Identification of Endgroups
III. The Primary Structure of Viral RNA
IV. Sequences of the Viral RNA not Involved in Translation
V. Sequences of the Viral RNA which Contain the Message for Polypeptide Synthesis
VI. Physical Structure of the Viral RNA
Note Added in Proof
Acknowledgments
References
15. Thermodynamics and Kinetics of Conformational Transitions in Oligonucleotides and tRNA
I. Introduction
II. Single Strand Stacking
III. Base Pairing in Oligonucleotides and tRNA Fragments
IV. Conformational Changes in tRNA
V. Biological Implications
Acknowledgments
Addendum
References
16. Hydrodynamic Properties and Conformational Changes of Linear Native DNA
I. Introduction
II. Theoretical Aspects of DNA Hydrodynamics
III. Special Experimental Aspects of DNA Hydrodynamics and Molecular Weight Determination
IV. Hydrodynamic Behavior and DNA Molecular Weight
V. DNA as a Polyelectrolyte
VI. Analysis of Induced DNA Conformational Changes
Acknowledgments
References
Author Index
Subject Index
- Edition: 1
- Latest edition
- Published: January 1, 1973
- Language: English
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